| Full name: TSC22 domain family member 1 | Alias Symbol: TSC22|MGC17597 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 8848 | HGNC ID: HGNC:16826 | Ensembl Gene: ENSG00000102804 | OMIM ID: 607715 |
| Drug and gene relationship at DGIdb | |||
Expression of TSC22D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSC22D1 | 8848 | 215111_s_at | -0.5972 | 0.2376 | |
| GSE20347 | TSC22D1 | 8848 | 215111_s_at | 0.0772 | 0.7671 | |
| GSE23400 | TSC22D1 | 8848 | 215111_s_at | -0.0902 | 0.4823 | |
| GSE26886 | TSC22D1 | 8848 | 215111_s_at | 1.5159 | 0.0002 | |
| GSE29001 | TSC22D1 | 8848 | 215111_s_at | -0.1330 | 0.7676 | |
| GSE38129 | TSC22D1 | 8848 | 215111_s_at | -0.1897 | 0.4262 | |
| GSE45670 | TSC22D1 | 8848 | 215111_s_at | -0.7443 | 0.0087 | |
| GSE53622 | TSC22D1 | 8848 | 95774 | -0.5633 | 0.0000 | |
| GSE53624 | TSC22D1 | 8848 | 95774 | -0.4036 | 0.0000 | |
| GSE63941 | TSC22D1 | 8848 | 215111_s_at | 0.0963 | 0.8621 | |
| GSE77861 | TSC22D1 | 8848 | 215111_s_at | 1.2636 | 0.0031 | |
| GSE97050 | TSC22D1 | 8848 | A_33_P3296205 | -0.2221 | 0.7323 | |
| SRP007169 | TSC22D1 | 8848 | RNAseq | 0.1324 | 0.7383 | |
| SRP008496 | TSC22D1 | 8848 | RNAseq | 0.5485 | 0.0499 | |
| SRP064894 | TSC22D1 | 8848 | RNAseq | -0.2310 | 0.2993 | |
| SRP133303 | TSC22D1 | 8848 | RNAseq | -0.0306 | 0.9028 | |
| SRP159526 | TSC22D1 | 8848 | RNAseq | -0.6112 | 0.0802 | |
| SRP193095 | TSC22D1 | 8848 | RNAseq | 0.5132 | 0.0109 | |
| SRP219564 | TSC22D1 | 8848 | RNAseq | -0.0172 | 0.9735 | |
| TCGA | TSC22D1 | 8848 | RNAseq | -0.2498 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TSC22D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSC22D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSC22D1 | 8848 | 0 | 13 | 17 | |
| GSE20123 | TSC22D1 | 8848 | 0 | 12 | 18 | |
| GSE43470 | TSC22D1 | 8848 | 3 | 13 | 27 | |
| GSE46452 | TSC22D1 | 8848 | 0 | 33 | 26 | |
| GSE47630 | TSC22D1 | 8848 | 2 | 27 | 11 | |
| GSE54993 | TSC22D1 | 8848 | 12 | 2 | 56 | |
| GSE54994 | TSC22D1 | 8848 | 1 | 16 | 36 | |
| GSE60625 | TSC22D1 | 8848 | 0 | 3 | 8 | |
| GSE74703 | TSC22D1 | 8848 | 3 | 10 | 23 | |
| GSE74704 | TSC22D1 | 8848 | 0 | 9 | 11 | |
| TCGA | TSC22D1 | 8848 | 8 | 39 | 49 |
Total number of gains: 29; Total number of losses: 177; Total Number of normals: 282.
Somatic mutations of TSC22D1:
Generating mutation plots.
Highly correlated genes for TSC22D1:
Showing top 20/1034 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSC22D1 | NEO1 | 0.790037 | 3 | 0 | 3 |
| TSC22D1 | TMED8 | 0.780837 | 3 | 0 | 3 |
| TSC22D1 | TRRAP | 0.777974 | 3 | 0 | 3 |
| TSC22D1 | RILPL1 | 0.771874 | 3 | 0 | 3 |
| TSC22D1 | PDK2 | 0.771008 | 3 | 0 | 3 |
| TSC22D1 | WSCD2 | 0.763772 | 3 | 0 | 3 |
| TSC22D1 | DYNC2LI1 | 0.755837 | 3 | 0 | 3 |
| TSC22D1 | ZCCHC3 | 0.754107 | 3 | 0 | 3 |
| TSC22D1 | RAD23A | 0.752785 | 3 | 0 | 3 |
| TSC22D1 | RBMX2 | 0.745036 | 4 | 0 | 4 |
| TSC22D1 | MED30 | 0.739194 | 3 | 0 | 3 |
| TSC22D1 | EMILIN2 | 0.737381 | 3 | 0 | 3 |
| TSC22D1 | FGF12 | 0.736447 | 4 | 0 | 4 |
| TSC22D1 | RASD2 | 0.729811 | 3 | 0 | 3 |
| TSC22D1 | ASAP1 | 0.726388 | 3 | 0 | 3 |
| TSC22D1 | TMTC1 | 0.721391 | 5 | 0 | 4 |
| TSC22D1 | LCLAT1 | 0.721282 | 3 | 0 | 3 |
| TSC22D1 | MAPKAPK5 | 0.71663 | 3 | 0 | 3 |
| TSC22D1 | FXYD1 | 0.715127 | 4 | 0 | 3 |
| TSC22D1 | MFHAS1 | 0.713413 | 3 | 0 | 3 |
For details and further investigation, click here
