| Full name: abhydrolase domain containing 3 | Alias Symbol: LABH3 | ||
| Type: protein-coding gene | Cytoband: 18q11.2 | ||
| Entrez ID: 171586 | HGNC ID: HGNC:18718 | Ensembl Gene: ENSG00000158201 | OMIM ID: 612197 |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD3 | 171586 | 213017_at | -0.0810 | 0.9204 | |
| GSE20347 | ABHD3 | 171586 | 213017_at | -0.1232 | 0.5767 | |
| GSE23400 | ABHD3 | 171586 | 213017_at | 0.0902 | 0.2988 | |
| GSE26886 | ABHD3 | 171586 | 213017_at | -0.6093 | 0.0457 | |
| GSE29001 | ABHD3 | 171586 | 213017_at | -0.3499 | 0.5068 | |
| GSE38129 | ABHD3 | 171586 | 213017_at | 0.3162 | 0.1682 | |
| GSE45670 | ABHD3 | 171586 | 213017_at | 0.3363 | 0.0632 | |
| GSE53622 | ABHD3 | 171586 | 10780 | -0.0303 | 0.8302 | |
| GSE53624 | ABHD3 | 171586 | 10780 | -0.3853 | 0.0014 | |
| GSE63941 | ABHD3 | 171586 | 213017_at | 2.4045 | 0.0001 | |
| GSE77861 | ABHD3 | 171586 | 213017_at | -0.0679 | 0.8754 | |
| GSE97050 | ABHD3 | 171586 | A_23_P305759 | 0.0749 | 0.8443 | |
| SRP007169 | ABHD3 | 171586 | RNAseq | -0.4466 | 0.1871 | |
| SRP008496 | ABHD3 | 171586 | RNAseq | -0.7395 | 0.0081 | |
| SRP064894 | ABHD3 | 171586 | RNAseq | -0.6488 | 0.0165 | |
| SRP133303 | ABHD3 | 171586 | RNAseq | 0.2698 | 0.3038 | |
| SRP159526 | ABHD3 | 171586 | RNAseq | 0.3908 | 0.3217 | |
| SRP193095 | ABHD3 | 171586 | RNAseq | -0.5321 | 0.0012 | |
| SRP219564 | ABHD3 | 171586 | RNAseq | -0.2033 | 0.7367 | |
| TCGA | ABHD3 | 171586 | RNAseq | -0.0121 | 0.8846 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ABHD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD3 | 171586 | 2 | 6 | 22 | |
| GSE20123 | ABHD3 | 171586 | 1 | 6 | 23 | |
| GSE43470 | ABHD3 | 171586 | 2 | 1 | 40 | |
| GSE46452 | ABHD3 | 171586 | 3 | 22 | 34 | |
| GSE47630 | ABHD3 | 171586 | 7 | 17 | 16 | |
| GSE54993 | ABHD3 | 171586 | 7 | 1 | 62 | |
| GSE54994 | ABHD3 | 171586 | 3 | 12 | 38 | |
| GSE60625 | ABHD3 | 171586 | 0 | 4 | 7 | |
| GSE74703 | ABHD3 | 171586 | 2 | 1 | 33 | |
| GSE74704 | ABHD3 | 171586 | 1 | 5 | 14 | |
| TCGA | ABHD3 | 171586 | 18 | 18 | 60 |
Total number of gains: 46; Total number of losses: 93; Total Number of normals: 349.
Somatic mutations of ABHD3:
Generating mutation plots.
Highly correlated genes for ABHD3:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD3 | MOB4 | 0.763686 | 3 | 0 | 3 |
| ABHD3 | MED30 | 0.760303 | 3 | 0 | 3 |
| ABHD3 | RPUSD3 | 0.734368 | 3 | 0 | 3 |
| ABHD3 | DDX18 | 0.725875 | 3 | 0 | 3 |
| ABHD3 | ZNF416 | 0.715787 | 3 | 0 | 3 |
| ABHD3 | BORA | 0.713011 | 3 | 0 | 3 |
| ABHD3 | ARGLU1 | 0.709988 | 3 | 0 | 3 |
| ABHD3 | ADAM11 | 0.703404 | 3 | 0 | 3 |
| ABHD3 | BACE2 | 0.700045 | 3 | 0 | 3 |
| ABHD3 | ARL6IP6 | 0.699046 | 3 | 0 | 3 |
| ABHD3 | SLC33A1 | 0.698757 | 3 | 0 | 3 |
| ABHD3 | ZDHHC21 | 0.697122 | 3 | 0 | 3 |
| ABHD3 | CHAF1B | 0.692939 | 3 | 0 | 3 |
| ABHD3 | ARG2 | 0.692071 | 3 | 0 | 3 |
| ABHD3 | ACADM | 0.690763 | 3 | 0 | 3 |
| ABHD3 | ZNF101 | 0.689082 | 4 | 0 | 3 |
| ABHD3 | USP8 | 0.688132 | 4 | 0 | 3 |
| ABHD3 | ILF2 | 0.687986 | 3 | 0 | 3 |
| ABHD3 | SLC7A1 | 0.686874 | 3 | 0 | 3 |
| ABHD3 | MGAT4A | 0.684082 | 4 | 0 | 3 |
For details and further investigation, click here
