| Full name: methyltransferase like 6 | Alias Symbol: MGC24132 | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 131965 | HGNC ID: HGNC:28343 | Ensembl Gene: ENSG00000206562 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of METTL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL6 | 131965 | 1553689_s_at | 0.4122 | 0.4312 | |
| GSE26886 | METTL6 | 131965 | 1553689_s_at | 0.2647 | 0.2121 | |
| GSE45670 | METTL6 | 131965 | 1553689_s_at | 0.2603 | 0.0518 | |
| GSE53622 | METTL6 | 131965 | 10930 | -0.1306 | 0.0268 | |
| GSE53624 | METTL6 | 131965 | 10930 | 0.0887 | 0.3990 | |
| GSE63941 | METTL6 | 131965 | 1553689_s_at | 0.1516 | 0.7810 | |
| GSE77861 | METTL6 | 131965 | 1553688_at | -0.1568 | 0.0716 | |
| GSE97050 | METTL6 | 131965 | A_23_P361469 | 0.1355 | 0.5830 | |
| SRP007169 | METTL6 | 131965 | RNAseq | -0.5030 | 0.2637 | |
| SRP008496 | METTL6 | 131965 | RNAseq | 0.1395 | 0.6771 | |
| SRP064894 | METTL6 | 131965 | RNAseq | 0.1553 | 0.2716 | |
| SRP133303 | METTL6 | 131965 | RNAseq | -0.1228 | 0.4086 | |
| SRP159526 | METTL6 | 131965 | RNAseq | -0.3395 | 0.1508 | |
| SRP193095 | METTL6 | 131965 | RNAseq | -0.1874 | 0.0310 | |
| SRP219564 | METTL6 | 131965 | RNAseq | -0.1116 | 0.6006 | |
| TCGA | METTL6 | 131965 | RNAseq | 0.0022 | 0.9738 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by METTL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL6 | 131965 | 2 | 19 | 9 | |
| GSE20123 | METTL6 | 131965 | 2 | 19 | 9 | |
| GSE43470 | METTL6 | 131965 | 0 | 21 | 22 | |
| GSE46452 | METTL6 | 131965 | 2 | 17 | 40 | |
| GSE47630 | METTL6 | 131965 | 2 | 23 | 15 | |
| GSE54993 | METTL6 | 131965 | 6 | 1 | 63 | |
| GSE54994 | METTL6 | 131965 | 1 | 32 | 20 | |
| GSE60625 | METTL6 | 131965 | 5 | 0 | 6 | |
| GSE74703 | METTL6 | 131965 | 0 | 17 | 19 | |
| GSE74704 | METTL6 | 131965 | 1 | 13 | 6 | |
| TCGA | METTL6 | 131965 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 230; Total Number of normals: 235.
Somatic mutations of METTL6:
Generating mutation plots.
Highly correlated genes for METTL6:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL6 | CEPT1 | 0.676591 | 3 | 0 | 3 |
| METTL6 | GPR158 | 0.659373 | 3 | 0 | 3 |
| METTL6 | MRPL1 | 0.659264 | 3 | 0 | 3 |
| METTL6 | STT3B | 0.652449 | 3 | 0 | 3 |
| METTL6 | EIF5A | 0.644126 | 3 | 0 | 3 |
| METTL6 | SUSD1 | 0.637788 | 4 | 0 | 4 |
| METTL6 | EBAG9 | 0.636264 | 3 | 0 | 3 |
| METTL6 | PSMB7 | 0.634739 | 3 | 0 | 3 |
| METTL6 | PPIB | 0.631664 | 3 | 0 | 3 |
| METTL6 | FCRL4 | 0.62144 | 4 | 0 | 4 |
| METTL6 | TMEM160 | 0.62066 | 3 | 0 | 3 |
| METTL6 | CCDC126 | 0.620343 | 4 | 0 | 4 |
| METTL6 | C9orf64 | 0.615673 | 3 | 0 | 3 |
| METTL6 | COQ3 | 0.614094 | 3 | 0 | 3 |
| METTL6 | BRMS1L | 0.6136 | 5 | 0 | 4 |
| METTL6 | CEP128 | 0.608005 | 6 | 0 | 5 |
| METTL6 | TEX30 | 0.607729 | 3 | 0 | 3 |
| METTL6 | RAD51B | 0.607425 | 4 | 0 | 3 |
| METTL6 | NRDE2 | 0.605475 | 5 | 0 | 3 |
| METTL6 | RMI1 | 0.605141 | 3 | 0 | 3 |
For details and further investigation, click here
