CCDC126

 

Full name: coiled-coil domain containing 126 Alias Symbol: FLJ23031
Type: protein-coding gene Cytoband: 7p15.3
Entrez ID: 90693 HGNC ID: HGNC:22398 Ensembl Gene: ENSG00000169193 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CCDC126:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC126 90693 228087_at 0.0016 0.9987
GSE26886 CCDC126 90693 228087_at -0.6113 0.0857
GSE45670 CCDC126 90693 228087_at -0.2476 0.2155
GSE53622 CCDC126 90693 22562 -0.0897 0.3878
GSE53624 CCDC126 90693 22562 -0.4745 0.0001
GSE63941 CCDC126 90693 228087_at -0.8474 0.1971
GSE77861 CCDC126 90693 228087_at -0.1770 0.4662
GSE97050 CCDC126 90693 A_23_P168592 0.1960 0.4148
SRP007169 CCDC126 90693 RNAseq -1.3948 0.0088
SRP008496 CCDC126 90693 RNAseq -0.8756 0.0084
SRP064894 CCDC126 90693 RNAseq -0.5419 0.0132
SRP133303 CCDC126 90693 RNAseq 0.1826 0.2821
SRP159526 CCDC126 90693 RNAseq -0.1139 0.7657
SRP193095 CCDC126 90693 RNAseq -0.4939 0.0026
SRP219564 CCDC126 90693 RNAseq -0.8384 0.0254
TCGA CCDC126 90693 RNAseq -0.1047 0.2460

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by CCDC126 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CCDC126:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC126 90693 17 1 12
GSE20123 CCDC126 90693 17 1 12
GSE43470 CCDC126 90693 4 0 39
GSE46452 CCDC126 90693 10 2 47
GSE47630 CCDC126 90693 9 1 30
GSE54993 CCDC126 90693 0 6 64
GSE54994 CCDC126 90693 20 2 31
GSE60625 CCDC126 90693 0 0 11
GSE74703 CCDC126 90693 4 0 32
GSE74704 CCDC126 90693 11 1 8
TCGA CCDC126 90693 56 4 36

Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.  


 

Somatic mutations of CCDC126:

 

Generating mutation plots.

 

Highly correlated genes for CCDC126:

 

Showing top 20/367 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC126MRPL460.771637404
CCDC126KLHL70.743209303
CCDC126PALB20.733601303
CCDC126MFN10.730844303
CCDC126TMEM1170.724176303
CCDC126SLC38A90.722557404
CCDC126TRAPPC130.714834404
CCDC126NARS20.712068303
CCDC126SRFBP10.702989404
CCDC126NAPG0.702367303
CCDC126TM4SF180.699452303
CCDC126PLEKHA80.692268303
CCDC126FYTTD10.691506303
CCDC126RAD170.685303504
CCDC126SENP80.680658404
CCDC126UBE2F0.674199303
CCDC126CYP1A20.672849303
CCDC126ZNF700.671384303
CCDC126CUL4B0.671052403
CCDC126ACVR2A0.664588303

For details and further investigation, click here