| Full name: G protein-coupled receptor 158 | Alias Symbol: KIAA1136 | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 57512 | HGNC ID: HGNC:23689 | Ensembl Gene: ENSG00000151025 | OMIM ID: 614573 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR158:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR158 | 57512 | 232195_at | 2.0676 | 0.0523 | |
| GSE26886 | GPR158 | 57512 | 232195_at | 1.3858 | 0.0010 | |
| GSE45670 | GPR158 | 57512 | 232195_at | 1.8488 | 0.0007 | |
| GSE53622 | GPR158 | 57512 | 97374 | 3.4698 | 0.0000 | |
| GSE53624 | GPR158 | 57512 | 97374 | 4.2146 | 0.0000 | |
| GSE63941 | GPR158 | 57512 | 232195_at | 2.3761 | 0.1091 | |
| GSE77861 | GPR158 | 57512 | 232195_at | 0.1556 | 0.5111 | |
| GSE97050 | GPR158 | 57512 | A_24_P349117 | 0.4442 | 0.1819 | |
| SRP159526 | GPR158 | 57512 | RNAseq | 7.6445 | 0.0000 | |
| SRP219564 | GPR158 | 57512 | RNAseq | 4.9745 | 0.0000 | |
| TCGA | GPR158 | 57512 | RNAseq | 0.9485 | 0.0200 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by GPR158 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR158:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR158 | 57512 | 5 | 7 | 18 | |
| GSE20123 | GPR158 | 57512 | 5 | 6 | 19 | |
| GSE43470 | GPR158 | 57512 | 4 | 4 | 35 | |
| GSE46452 | GPR158 | 57512 | 1 | 14 | 44 | |
| GSE47630 | GPR158 | 57512 | 5 | 15 | 20 | |
| GSE54993 | GPR158 | 57512 | 9 | 0 | 61 | |
| GSE54994 | GPR158 | 57512 | 3 | 9 | 41 | |
| GSE60625 | GPR158 | 57512 | 0 | 0 | 11 | |
| GSE74703 | GPR158 | 57512 | 3 | 2 | 31 | |
| GSE74704 | GPR158 | 57512 | 0 | 5 | 15 | |
| TCGA | GPR158 | 57512 | 18 | 24 | 54 |
Total number of gains: 53; Total number of losses: 86; Total Number of normals: 349.
Somatic mutations of GPR158:
Generating mutation plots.
Highly correlated genes for GPR158:
Showing top 20/1258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR158 | MICALCL | 0.779758 | 3 | 0 | 3 |
| GPR158 | MGAT4B | 0.763409 | 3 | 0 | 3 |
| GPR158 | ZBTB11 | 0.759674 | 3 | 0 | 3 |
| GPR158 | ARHGEF19 | 0.758926 | 3 | 0 | 3 |
| GPR158 | CHD4 | 0.757767 | 4 | 0 | 4 |
| GPR158 | CCDC15 | 0.754246 | 3 | 0 | 3 |
| GPR158 | SPNS1 | 0.743628 | 3 | 0 | 3 |
| GPR158 | INTS1 | 0.740841 | 4 | 0 | 4 |
| GPR158 | LRRC39 | 0.735196 | 3 | 0 | 3 |
| GPR158 | UBA2 | 0.734243 | 3 | 0 | 3 |
| GPR158 | AZIN1 | 0.733414 | 3 | 0 | 3 |
| GPR158 | C1orf112 | 0.733364 | 4 | 0 | 4 |
| GPR158 | TMEM223 | 0.728801 | 3 | 0 | 3 |
| GPR158 | NEDD1 | 0.727521 | 6 | 0 | 6 |
| GPR158 | GPR153 | 0.726976 | 5 | 0 | 4 |
| GPR158 | SCAI | 0.725397 | 3 | 0 | 3 |
| GPR158 | POFUT1 | 0.725174 | 4 | 0 | 4 |
| GPR158 | DHTKD1 | 0.723839 | 4 | 0 | 3 |
| GPR158 | KDM1A | 0.721857 | 6 | 0 | 6 |
| GPR158 | NOC2L | 0.721324 | 3 | 0 | 3 |
For details and further investigation, click here
