| Full name: coenzyme Q3, methyltransferase | Alias Symbol: bA9819.1 | ||
| Type: protein-coding gene | Cytoband: 6q16.2 | ||
| Entrez ID: 51805 | HGNC ID: HGNC:18175 | Ensembl Gene: ENSG00000132423 | OMIM ID: 605196 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COQ3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COQ3 | 51805 | 223515_s_at | 0.0239 | 0.9516 | |
| GSE20347 | COQ3 | 51805 | 221227_x_at | 0.4270 | 0.0020 | |
| GSE23400 | COQ3 | 51805 | 221227_x_at | 0.0259 | 0.6827 | |
| GSE26886 | COQ3 | 51805 | 223515_s_at | 0.1664 | 0.4171 | |
| GSE29001 | COQ3 | 51805 | 221227_x_at | 0.3654 | 0.1310 | |
| GSE38129 | COQ3 | 51805 | 221227_x_at | 0.2479 | 0.0164 | |
| GSE45670 | COQ3 | 51805 | 223515_s_at | 0.4146 | 0.0056 | |
| GSE53622 | COQ3 | 51805 | 82593 | 0.2604 | 0.0054 | |
| GSE53624 | COQ3 | 51805 | 82593 | 0.5488 | 0.0000 | |
| GSE63941 | COQ3 | 51805 | 223515_s_at | 1.0164 | 0.0972 | |
| GSE77861 | COQ3 | 51805 | 223515_s_at | 0.2178 | 0.5237 | |
| GSE97050 | COQ3 | 51805 | A_23_P111228 | 0.2440 | 0.3748 | |
| SRP007169 | COQ3 | 51805 | RNAseq | 0.6140 | 0.3019 | |
| SRP008496 | COQ3 | 51805 | RNAseq | 1.0266 | 0.0279 | |
| SRP064894 | COQ3 | 51805 | RNAseq | 0.2419 | 0.3023 | |
| SRP133303 | COQ3 | 51805 | RNAseq | 0.2229 | 0.2982 | |
| SRP159526 | COQ3 | 51805 | RNAseq | 0.4929 | 0.0245 | |
| SRP193095 | COQ3 | 51805 | RNAseq | -0.0298 | 0.8084 | |
| SRP219564 | COQ3 | 51805 | RNAseq | -0.0473 | 0.8825 | |
| TCGA | COQ3 | 51805 | RNAseq | 0.2006 | 0.0139 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by COQ3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COQ3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COQ3 | 51805 | 2 | 3 | 25 | |
| GSE20123 | COQ3 | 51805 | 2 | 2 | 26 | |
| GSE43470 | COQ3 | 51805 | 3 | 0 | 40 | |
| GSE46452 | COQ3 | 51805 | 2 | 11 | 46 | |
| GSE47630 | COQ3 | 51805 | 8 | 6 | 26 | |
| GSE54993 | COQ3 | 51805 | 3 | 2 | 65 | |
| GSE54994 | COQ3 | 51805 | 8 | 8 | 37 | |
| GSE60625 | COQ3 | 51805 | 0 | 1 | 10 | |
| GSE74703 | COQ3 | 51805 | 2 | 0 | 34 | |
| GSE74704 | COQ3 | 51805 | 1 | 0 | 19 | |
| TCGA | COQ3 | 51805 | 7 | 24 | 65 |
Total number of gains: 38; Total number of losses: 57; Total Number of normals: 393.
Somatic mutations of COQ3:
Generating mutation plots.
Highly correlated genes for COQ3:
Showing top 20/931 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COQ3 | FAM118B | 0.750703 | 3 | 0 | 3 |
| COQ3 | TOR1A | 0.734412 | 3 | 0 | 3 |
| COQ3 | KIAA1586 | 0.729701 | 3 | 0 | 3 |
| COQ3 | MAT2B | 0.726569 | 3 | 0 | 3 |
| COQ3 | RTN4IP1 | 0.72426 | 8 | 0 | 8 |
| COQ3 | LCMT2 | 0.718346 | 3 | 0 | 3 |
| COQ3 | GTF2A2 | 0.707181 | 3 | 0 | 3 |
| COQ3 | USP12 | 0.70408 | 3 | 0 | 3 |
| COQ3 | MMS22L | 0.701155 | 3 | 0 | 3 |
| COQ3 | RAD18 | 0.700734 | 3 | 0 | 3 |
| COQ3 | AGPAT5 | 0.695925 | 4 | 0 | 4 |
| COQ3 | NOM1 | 0.695696 | 3 | 0 | 3 |
| COQ3 | DGKH | 0.695239 | 3 | 0 | 3 |
| COQ3 | SLC39A10 | 0.688131 | 3 | 0 | 3 |
| COQ3 | DHX37 | 0.686615 | 3 | 0 | 3 |
| COQ3 | COPS4 | 0.685924 | 3 | 0 | 3 |
| COQ3 | PITX2 | 0.685313 | 3 | 0 | 3 |
| COQ3 | LRRC8B | 0.684986 | 4 | 0 | 3 |
| COQ3 | TYW3 | 0.683278 | 3 | 0 | 3 |
| COQ3 | SH2B3 | 0.682782 | 3 | 0 | 3 |
For details and further investigation, click here
