| Full name: RAD51 paralog B | Alias Symbol: REC2|hREC2|R51H2 | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 5890 | HGNC ID: HGNC:9822 | Ensembl Gene: ENSG00000182185 | OMIM ID: 602948 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RAD51B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD51B | 5890 | 210255_at | 0.3558 | 0.5013 | |
| GSE20347 | RAD51B | 5890 | 210255_at | 0.0739 | 0.6044 | |
| GSE23400 | RAD51B | 5890 | 216880_at | 0.0303 | 0.3397 | |
| GSE26886 | RAD51B | 5890 | 216880_at | 0.3971 | 0.0180 | |
| GSE29001 | RAD51B | 5890 | 216880_at | 0.9689 | 0.0040 | |
| GSE38129 | RAD51B | 5890 | 210255_at | 0.2373 | 0.0938 | |
| GSE45670 | RAD51B | 5890 | 210255_at | -0.0075 | 0.9795 | |
| GSE53622 | RAD51B | 5890 | 110034 | 0.5383 | 0.0000 | |
| GSE53624 | RAD51B | 5890 | 110034 | 0.4794 | 0.0000 | |
| GSE63941 | RAD51B | 5890 | 210255_at | 1.1765 | 0.1443 | |
| GSE77861 | RAD51B | 5890 | 1554496_at | -0.2162 | 0.0090 | |
| GSE97050 | RAD51B | 5890 | A_23_P48481 | 0.5460 | 0.1633 | |
| SRP007169 | RAD51B | 5890 | RNAseq | 0.4165 | 0.4940 | |
| SRP008496 | RAD51B | 5890 | RNAseq | 0.5418 | 0.2271 | |
| SRP064894 | RAD51B | 5890 | RNAseq | 0.5440 | 0.0030 | |
| SRP133303 | RAD51B | 5890 | RNAseq | 0.4292 | 0.0856 | |
| SRP159526 | RAD51B | 5890 | RNAseq | 0.2025 | 0.6123 | |
| SRP193095 | RAD51B | 5890 | RNAseq | 0.4259 | 0.0050 | |
| SRP219564 | RAD51B | 5890 | RNAseq | 0.3431 | 0.4750 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAD51B expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RAD51B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD51B | 5890 | 9 | 2 | 19 | |
| GSE20123 | RAD51B | 5890 | 9 | 2 | 19 | |
| GSE43470 | RAD51B | 5890 | 8 | 2 | 33 | |
| GSE46452 | RAD51B | 5890 | 16 | 3 | 40 | |
| GSE47630 | RAD51B | 5890 | 11 | 9 | 20 | |
| GSE54993 | RAD51B | 5890 | 3 | 9 | 58 | |
| GSE54994 | RAD51B | 5890 | 18 | 5 | 30 | |
| GSE60625 | RAD51B | 5890 | 0 | 2 | 9 | |
| GSE74703 | RAD51B | 5890 | 7 | 2 | 27 | |
| GSE74704 | RAD51B | 5890 | 4 | 2 | 14 | |
| TCGA | RAD51B | 5890 | 33 | 17 | 46 |
Total number of gains: 118; Total number of losses: 55; Total Number of normals: 315.
Somatic mutations of RAD51B:
Generating mutation plots.
Highly correlated genes for RAD51B:
Showing top 20/169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD51B | FANCM | 0.739715 | 4 | 0 | 4 |
| RAD51B | ARF6 | 0.738346 | 3 | 0 | 3 |
| RAD51B | UBE2F | 0.722824 | 3 | 0 | 3 |
| RAD51B | GK5 | 0.694601 | 3 | 0 | 3 |
| RAD51B | NOP56 | 0.683543 | 3 | 0 | 3 |
| RAD51B | FAM83A | 0.678118 | 3 | 0 | 3 |
| RAD51B | SLC15A2 | 0.670514 | 3 | 0 | 3 |
| RAD51B | UBTD2 | 0.663474 | 4 | 0 | 4 |
| RAD51B | CEP128 | 0.661305 | 5 | 0 | 5 |
| RAD51B | TDO2 | 0.650382 | 3 | 0 | 3 |
| RAD51B | ANGEL1 | 0.648866 | 6 | 0 | 5 |
| RAD51B | VPS52 | 0.647831 | 3 | 0 | 3 |
| RAD51B | NDFIP2 | 0.647031 | 3 | 0 | 3 |
| RAD51B | AFAP1L1 | 0.645307 | 4 | 0 | 4 |
| RAD51B | COQ2 | 0.643002 | 3 | 0 | 3 |
| RAD51B | IFNLR1 | 0.641857 | 3 | 0 | 3 |
| RAD51B | SUSD1 | 0.637595 | 3 | 0 | 3 |
| RAD51B | ZNF718 | 0.636051 | 3 | 0 | 3 |
| RAD51B | KTI12 | 0.634333 | 3 | 0 | 3 |
| RAD51B | AP1S3 | 0.630069 | 4 | 0 | 3 |
For details and further investigation, click here
