| Full name: major facilitator superfamily domain containing 6 | Alias Symbol: FLJ20160 | ||
| Type: protein-coding gene | Cytoband: 2q32.2 | ||
| Entrez ID: 54842 | HGNC ID: HGNC:24711 | Ensembl Gene: ENSG00000151690 | OMIM ID: 613476 |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD6 | 54842 | 225325_at | -0.8744 | 0.0213 | |
| GSE20347 | MFSD6 | 54842 | 219858_s_at | -0.7924 | 0.0002 | |
| GSE23400 | MFSD6 | 54842 | 219858_s_at | -0.1899 | 0.0011 | |
| GSE26886 | MFSD6 | 54842 | 225325_at | -1.4260 | 0.0000 | |
| GSE29001 | MFSD6 | 54842 | 219858_s_at | -0.6265 | 0.2631 | |
| GSE38129 | MFSD6 | 54842 | 219858_s_at | -0.2741 | 0.3119 | |
| GSE45670 | MFSD6 | 54842 | 225325_at | -0.4070 | 0.0572 | |
| GSE53622 | MFSD6 | 54842 | 41359 | -0.9028 | 0.0000 | |
| GSE53624 | MFSD6 | 54842 | 41359 | -0.9530 | 0.0000 | |
| GSE63941 | MFSD6 | 54842 | 225325_at | -0.7481 | 0.1670 | |
| GSE77861 | MFSD6 | 54842 | 225325_at | -0.4545 | 0.0460 | |
| GSE97050 | MFSD6 | 54842 | A_33_P3272209 | -0.0570 | 0.8928 | |
| SRP007169 | MFSD6 | 54842 | RNAseq | -1.2487 | 0.0001 | |
| SRP008496 | MFSD6 | 54842 | RNAseq | -1.2682 | 0.0000 | |
| SRP064894 | MFSD6 | 54842 | RNAseq | -0.8069 | 0.0005 | |
| SRP133303 | MFSD6 | 54842 | RNAseq | -0.6136 | 0.0094 | |
| SRP159526 | MFSD6 | 54842 | RNAseq | -0.9556 | 0.0339 | |
| SRP193095 | MFSD6 | 54842 | RNAseq | -0.7967 | 0.0000 | |
| SRP219564 | MFSD6 | 54842 | RNAseq | -1.1234 | 0.0064 | |
| TCGA | MFSD6 | 54842 | RNAseq | -0.2065 | 0.0047 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MFSD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD6 | 54842 | 8 | 2 | 20 | |
| GSE20123 | MFSD6 | 54842 | 8 | 2 | 20 | |
| GSE43470 | MFSD6 | 54842 | 3 | 1 | 39 | |
| GSE46452 | MFSD6 | 54842 | 1 | 4 | 54 | |
| GSE47630 | MFSD6 | 54842 | 4 | 5 | 31 | |
| GSE54993 | MFSD6 | 54842 | 0 | 5 | 65 | |
| GSE54994 | MFSD6 | 54842 | 12 | 6 | 35 | |
| GSE60625 | MFSD6 | 54842 | 0 | 3 | 8 | |
| GSE74703 | MFSD6 | 54842 | 2 | 1 | 33 | |
| GSE74704 | MFSD6 | 54842 | 3 | 2 | 15 | |
| TCGA | MFSD6 | 54842 | 24 | 7 | 65 |
Total number of gains: 65; Total number of losses: 38; Total Number of normals: 385.
Somatic mutations of MFSD6:
Generating mutation plots.
Highly correlated genes for MFSD6:
Showing top 20/1428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD6 | LYRM7 | 0.786744 | 4 | 0 | 4 |
| MFSD6 | HDHD2 | 0.776256 | 4 | 0 | 4 |
| MFSD6 | EXOC6B | 0.764565 | 3 | 0 | 3 |
| MFSD6 | PPWD1 | 0.760474 | 3 | 0 | 3 |
| MFSD6 | RAB3D | 0.758338 | 6 | 0 | 6 |
| MFSD6 | SLC9A9 | 0.745531 | 7 | 0 | 7 |
| MFSD6 | TYSND1 | 0.741751 | 3 | 0 | 3 |
| MFSD6 | TMEM120A | 0.736825 | 6 | 0 | 6 |
| MFSD6 | PINK1 | 0.726835 | 5 | 0 | 5 |
| MFSD6 | COMMD1 | 0.724754 | 5 | 0 | 5 |
| MFSD6 | PLEKHA7 | 0.719045 | 7 | 0 | 7 |
| MFSD6 | RFFL | 0.713156 | 4 | 0 | 3 |
| MFSD6 | UBE4B | 0.712538 | 4 | 0 | 4 |
| MFSD6 | SNORA68 | 0.708786 | 4 | 0 | 4 |
| MFSD6 | MRPS36 | 0.708492 | 7 | 0 | 7 |
| MFSD6 | COG5 | 0.704158 | 3 | 0 | 3 |
| MFSD6 | KDM5D | 0.7038 | 3 | 0 | 3 |
| MFSD6 | GPR108 | 0.703509 | 3 | 0 | 3 |
| MFSD6 | SLC25A23 | 0.702795 | 6 | 0 | 6 |
| MFSD6 | ZNF613 | 0.697651 | 3 | 0 | 3 |
For details and further investigation, click here
