| Full name: trypsin domain containing 1 | Alias Symbol: MGC34695|NET41 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 219743 | HGNC ID: HGNC:28531 | Ensembl Gene: ENSG00000156521 | OMIM ID: 611017 |
| Drug and gene relationship at DGIdb | |||
Expression of TYSND1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TYSND1 | 219743 | 225877_at | 0.0316 | 0.9697 | |
| GSE26886 | TYSND1 | 219743 | 225877_at | -0.4044 | 0.0694 | |
| GSE45670 | TYSND1 | 219743 | 225877_at | 0.0941 | 0.6141 | |
| GSE53622 | TYSND1 | 219743 | 39937 | 0.2713 | 0.0122 | |
| GSE53624 | TYSND1 | 219743 | 110584 | 0.3098 | 0.0320 | |
| GSE63941 | TYSND1 | 219743 | 225877_at | 1.7646 | 0.0010 | |
| GSE77861 | TYSND1 | 219743 | 231422_x_at | -0.4187 | 0.0025 | |
| GSE97050 | TYSND1 | 219743 | A_33_P3351101 | 0.2518 | 0.2719 | |
| SRP007169 | TYSND1 | 219743 | RNAseq | -1.0022 | 0.0382 | |
| SRP008496 | TYSND1 | 219743 | RNAseq | -0.5900 | 0.0438 | |
| SRP064894 | TYSND1 | 219743 | RNAseq | -0.1581 | 0.4994 | |
| SRP133303 | TYSND1 | 219743 | RNAseq | -0.0299 | 0.8728 | |
| SRP159526 | TYSND1 | 219743 | RNAseq | -0.0640 | 0.8418 | |
| SRP193095 | TYSND1 | 219743 | RNAseq | -0.2684 | 0.0505 | |
| SRP219564 | TYSND1 | 219743 | RNAseq | 0.2637 | 0.6653 | |
| TCGA | TYSND1 | 219743 | RNAseq | 0.3613 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by TYSND1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TYSND1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TYSND1 | 219743 | 2 | 4 | 24 | |
| GSE20123 | TYSND1 | 219743 | 2 | 3 | 25 | |
| GSE43470 | TYSND1 | 219743 | 1 | 7 | 35 | |
| GSE46452 | TYSND1 | 219743 | 0 | 11 | 48 | |
| GSE47630 | TYSND1 | 219743 | 2 | 14 | 24 | |
| GSE54993 | TYSND1 | 219743 | 7 | 0 | 63 | |
| GSE54994 | TYSND1 | 219743 | 2 | 12 | 39 | |
| GSE60625 | TYSND1 | 219743 | 0 | 0 | 11 | |
| GSE74703 | TYSND1 | 219743 | 1 | 4 | 31 | |
| GSE74704 | TYSND1 | 219743 | 1 | 1 | 18 | |
| TCGA | TYSND1 | 219743 | 9 | 23 | 64 |
Total number of gains: 27; Total number of losses: 79; Total Number of normals: 382.
Somatic mutations of TYSND1:
Generating mutation plots.
Highly correlated genes for TYSND1:
Showing top 20/465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TYSND1 | VPS37B | 0.811107 | 3 | 0 | 3 |
| TYSND1 | HMGCS1 | 0.794424 | 3 | 0 | 3 |
| TYSND1 | NPRL2 | 0.789521 | 3 | 0 | 3 |
| TYSND1 | FAM83D | 0.78477 | 3 | 0 | 3 |
| TYSND1 | COBLL1 | 0.781164 | 3 | 0 | 3 |
| TYSND1 | NDUFA13 | 0.772816 | 4 | 0 | 4 |
| TYSND1 | DHX35 | 0.765367 | 3 | 0 | 3 |
| TYSND1 | DEFB119 | 0.757478 | 3 | 0 | 3 |
| TYSND1 | RNF10 | 0.75628 | 3 | 0 | 3 |
| TYSND1 | RREB1 | 0.754724 | 3 | 0 | 3 |
| TYSND1 | NANS | 0.753795 | 3 | 0 | 3 |
| TYSND1 | STAU2 | 0.752678 | 3 | 0 | 3 |
| TYSND1 | NUMA1 | 0.748847 | 3 | 0 | 3 |
| TYSND1 | ARPC3 | 0.745727 | 4 | 0 | 4 |
| TYSND1 | SLC15A2 | 0.745106 | 3 | 0 | 3 |
| TYSND1 | USP6NL | 0.743423 | 3 | 0 | 3 |
| TYSND1 | RAC1 | 0.743099 | 4 | 0 | 4 |
| TYSND1 | EPB41 | 0.742461 | 4 | 0 | 3 |
| TYSND1 | MFSD6 | 0.741751 | 3 | 0 | 3 |
| TYSND1 | TOM1L1 | 0.741291 | 3 | 0 | 3 |
For details and further investigation, click here
