| Full name: exocyst complex component 6B | Alias Symbol: KIAA0919 | ||
| Type: protein-coding gene | Cytoband: 2p13.2 | ||
| Entrez ID: 23233 | HGNC ID: HGNC:17085 | Ensembl Gene: ENSG00000144036 | OMIM ID: 607880 |
| Drug and gene relationship at DGIdb | |||
Expression of EXOC6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXOC6B | 23233 | 225900_at | 0.0906 | 0.9455 | |
| GSE20347 | EXOC6B | 23233 | 215417_at | -0.0562 | 0.4682 | |
| GSE23400 | EXOC6B | 23233 | 215417_at | 0.0003 | 0.9905 | |
| GSE26886 | EXOC6B | 23233 | 225900_at | -1.3997 | 0.0000 | |
| GSE29001 | EXOC6B | 23233 | 215417_at | -0.2730 | 0.2199 | |
| GSE38129 | EXOC6B | 23233 | 215417_at | 0.0692 | 0.5276 | |
| GSE45670 | EXOC6B | 23233 | 225900_at | 0.3513 | 0.1055 | |
| GSE53622 | EXOC6B | 23233 | 139276 | -0.0772 | 0.3698 | |
| GSE53624 | EXOC6B | 23233 | 139276 | -0.2317 | 0.0009 | |
| GSE63941 | EXOC6B | 23233 | 225900_at | -0.3780 | 0.4527 | |
| GSE77861 | EXOC6B | 23233 | 225900_at | 0.3828 | 0.3371 | |
| GSE97050 | EXOC6B | 23233 | A_33_P3232627 | -0.2211 | 0.4246 | |
| SRP007169 | EXOC6B | 23233 | RNAseq | -0.0741 | 0.8495 | |
| SRP008496 | EXOC6B | 23233 | RNAseq | -0.1086 | 0.6979 | |
| SRP064894 | EXOC6B | 23233 | RNAseq | -0.2814 | 0.2631 | |
| SRP133303 | EXOC6B | 23233 | RNAseq | 0.2888 | 0.2661 | |
| SRP159526 | EXOC6B | 23233 | RNAseq | 0.1483 | 0.5191 | |
| SRP193095 | EXOC6B | 23233 | RNAseq | -0.1986 | 0.1145 | |
| SRP219564 | EXOC6B | 23233 | RNAseq | -0.4047 | 0.3714 | |
| TCGA | EXOC6B | 23233 | RNAseq | 0.1092 | 0.1848 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EXOC6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXOC6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXOC6B | 23233 | 11 | 1 | 18 | |
| GSE20123 | EXOC6B | 23233 | 11 | 1 | 18 | |
| GSE43470 | EXOC6B | 23233 | 3 | 0 | 40 | |
| GSE46452 | EXOC6B | 23233 | 2 | 3 | 54 | |
| GSE47630 | EXOC6B | 23233 | 7 | 0 | 33 | |
| GSE54993 | EXOC6B | 23233 | 0 | 6 | 64 | |
| GSE54994 | EXOC6B | 23233 | 11 | 0 | 42 | |
| GSE60625 | EXOC6B | 23233 | 0 | 3 | 8 | |
| GSE74703 | EXOC6B | 23233 | 3 | 0 | 33 | |
| GSE74704 | EXOC6B | 23233 | 9 | 0 | 11 | |
| TCGA | EXOC6B | 23233 | 38 | 3 | 55 |
Total number of gains: 95; Total number of losses: 17; Total Number of normals: 376.
Somatic mutations of EXOC6B:
Generating mutation plots.
Highly correlated genes for EXOC6B:
Showing top 20/355 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXOC6B | CPPED1 | 0.832954 | 3 | 0 | 3 |
| EXOC6B | FAM114A2 | 0.812767 | 3 | 0 | 3 |
| EXOC6B | MOB4 | 0.788485 | 3 | 0 | 3 |
| EXOC6B | UBE2F | 0.778841 | 3 | 0 | 3 |
| EXOC6B | MALT1 | 0.773929 | 3 | 0 | 3 |
| EXOC6B | ATP6V1D | 0.767026 | 3 | 0 | 3 |
| EXOC6B | MFSD6 | 0.764565 | 3 | 0 | 3 |
| EXOC6B | RNF149 | 0.753072 | 3 | 0 | 3 |
| EXOC6B | SH3D19 | 0.749453 | 3 | 0 | 3 |
| EXOC6B | ACOX1 | 0.74758 | 3 | 0 | 3 |
| EXOC6B | LAMTOR3 | 0.739075 | 3 | 0 | 3 |
| EXOC6B | DMXL1 | 0.73798 | 3 | 0 | 3 |
| EXOC6B | KAT2B | 0.737319 | 3 | 0 | 3 |
| EXOC6B | ACTR3 | 0.733098 | 3 | 0 | 3 |
| EXOC6B | TRIM6 | 0.732218 | 3 | 0 | 3 |
| EXOC6B | HIGD1A | 0.732211 | 3 | 0 | 3 |
| EXOC6B | YIPF4 | 0.731896 | 4 | 0 | 4 |
| EXOC6B | NR2C2 | 0.731853 | 3 | 0 | 3 |
| EXOC6B | GBE1 | 0.728597 | 3 | 0 | 3 |
| EXOC6B | MED7 | 0.726312 | 3 | 0 | 3 |
For details and further investigation, click here
