| Full name: copper metabolism domain containing 1 | Alias Symbol: MURR1|MGC27155 | ||
| Type: protein-coding gene | Cytoband: 2p15 | ||
| Entrez ID: 150684 | HGNC ID: HGNC:23024 | Ensembl Gene: ENSG00000173163 | OMIM ID: 607238 |
| Drug and gene relationship at DGIdb | |||
Expression of COMMD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COMMD1 | 150684 | 226024_at | -0.4422 | 0.0739 | |
| GSE26886 | COMMD1 | 150684 | 226024_at | 0.0515 | 0.7843 | |
| GSE45670 | COMMD1 | 150684 | 226024_at | -0.4213 | 0.0017 | |
| GSE53622 | COMMD1 | 150684 | 82326 | -0.2350 | 0.0000 | |
| GSE53624 | COMMD1 | 150684 | 82326 | -0.4893 | 0.0000 | |
| GSE63941 | COMMD1 | 150684 | 226024_at | -0.3205 | 0.4894 | |
| GSE77861 | COMMD1 | 150684 | 226024_at | -0.5365 | 0.0381 | |
| GSE97050 | COMMD1 | 150684 | A_23_P389525 | -0.1439 | 0.4595 | |
| SRP007169 | COMMD1 | 150684 | RNAseq | -1.4688 | 0.0001 | |
| SRP008496 | COMMD1 | 150684 | RNAseq | -1.4889 | 0.0000 | |
| SRP064894 | COMMD1 | 150684 | RNAseq | -0.1627 | 0.5213 | |
| SRP133303 | COMMD1 | 150684 | RNAseq | -0.3779 | 0.0056 | |
| SRP159526 | COMMD1 | 150684 | RNAseq | 0.0045 | 0.9892 | |
| SRP193095 | COMMD1 | 150684 | RNAseq | -0.7199 | 0.0000 | |
| SRP219564 | COMMD1 | 150684 | RNAseq | -0.5477 | 0.0063 | |
| TCGA | COMMD1 | 150684 | RNAseq | -0.0055 | 0.9331 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by COMMD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COMMD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COMMD1 | 150684 | 12 | 0 | 18 | |
| GSE20123 | COMMD1 | 150684 | 12 | 0 | 18 | |
| GSE43470 | COMMD1 | 150684 | 7 | 0 | 36 | |
| GSE46452 | COMMD1 | 150684 | 2 | 3 | 54 | |
| GSE47630 | COMMD1 | 150684 | 8 | 0 | 32 | |
| GSE54993 | COMMD1 | 150684 | 0 | 6 | 64 | |
| GSE54994 | COMMD1 | 150684 | 12 | 0 | 41 | |
| GSE60625 | COMMD1 | 150684 | 0 | 3 | 8 | |
| GSE74703 | COMMD1 | 150684 | 7 | 0 | 29 | |
| GSE74704 | COMMD1 | 150684 | 10 | 0 | 10 | |
| TCGA | COMMD1 | 150684 | 36 | 2 | 58 |
Total number of gains: 106; Total number of losses: 14; Total Number of normals: 368.
Somatic mutations of COMMD1:
Generating mutation plots.
Highly correlated genes for COMMD1:
Showing top 20/923 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COMMD1 | PINK1 | 0.786258 | 4 | 0 | 3 |
| COMMD1 | MKRN2 | 0.783958 | 4 | 0 | 4 |
| COMMD1 | NSRP1 | 0.7694 | 3 | 0 | 3 |
| COMMD1 | UGP2 | 0.767084 | 4 | 0 | 4 |
| COMMD1 | DALRD3 | 0.762889 | 4 | 0 | 4 |
| COMMD1 | RHBDF1 | 0.762461 | 3 | 0 | 3 |
| COMMD1 | PPP2CA | 0.760634 | 3 | 0 | 3 |
| COMMD1 | UBE2D2 | 0.757303 | 3 | 0 | 3 |
| COMMD1 | ALG13 | 0.756138 | 3 | 0 | 3 |
| COMMD1 | PHKB | 0.754741 | 4 | 0 | 4 |
| COMMD1 | SFTA2 | 0.75301 | 3 | 0 | 3 |
| COMMD1 | TBC1D20 | 0.750595 | 3 | 0 | 3 |
| COMMD1 | LYSMD3 | 0.750341 | 3 | 0 | 3 |
| COMMD1 | CTR9 | 0.750045 | 3 | 0 | 3 |
| COMMD1 | TJP1 | 0.747321 | 4 | 0 | 4 |
| COMMD1 | FBXO3 | 0.741696 | 5 | 0 | 5 |
| COMMD1 | CRYL1 | 0.741655 | 6 | 0 | 5 |
| COMMD1 | RNH1 | 0.737924 | 4 | 0 | 4 |
| COMMD1 | GAB1 | 0.737051 | 5 | 0 | 4 |
| COMMD1 | USP25 | 0.73438 | 4 | 0 | 4 |
For details and further investigation, click here
