| Full name: MIA SH3 domain containing | Alias Symbol: CD-RAP | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 8190 | HGNC ID: HGNC:7076 | Ensembl Gene: ENSG00000261857 | OMIM ID: 601340 |
| Drug and gene relationship at DGIdb | |||
Expression of MIA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIA | 8190 | 206560_s_at | -0.5210 | 0.4420 | |
| GSE20347 | MIA | 8190 | 206560_s_at | 0.1855 | 0.5932 | |
| GSE23400 | MIA | 8190 | 206560_s_at | -0.2740 | 0.0000 | |
| GSE26886 | MIA | 8190 | 206560_s_at | 0.1854 | 0.1840 | |
| GSE29001 | MIA | 8190 | 206560_s_at | 0.3668 | 0.5403 | |
| GSE38129 | MIA | 8190 | 206560_s_at | -0.1964 | 0.4412 | |
| GSE45670 | MIA | 8190 | 206560_s_at | -0.5549 | 0.0001 | |
| GSE53622 | MIA | 8190 | 54450 | -1.3872 | 0.0003 | |
| GSE53624 | MIA | 8190 | 54450 | -1.8866 | 0.0000 | |
| GSE63941 | MIA | 8190 | 206560_s_at | 0.0267 | 0.9236 | |
| GSE77861 | MIA | 8190 | 206560_s_at | -0.1351 | 0.3670 | |
| GSE97050 | MIA | 8190 | A_23_P4714 | -0.1332 | 0.5608 | |
| SRP219564 | MIA | 8190 | RNAseq | -1.5161 | 0.0829 | |
| TCGA | MIA | 8190 | RNAseq | -0.7279 | 0.3139 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MIA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MIA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIA | 8190 | 4 | 5 | 21 | |
| GSE20123 | MIA | 8190 | 4 | 4 | 22 | |
| GSE43470 | MIA | 8190 | 3 | 9 | 31 | |
| GSE46452 | MIA | 8190 | 48 | 1 | 10 | |
| GSE47630 | MIA | 8190 | 9 | 5 | 26 | |
| GSE54993 | MIA | 8190 | 17 | 4 | 49 | |
| GSE54994 | MIA | 8190 | 8 | 9 | 36 | |
| GSE60625 | MIA | 8190 | 9 | 0 | 2 | |
| GSE74703 | MIA | 8190 | 3 | 6 | 27 | |
| GSE74704 | MIA | 8190 | 4 | 2 | 14 | |
| TCGA | MIA | 8190 | 14 | 16 | 66 |
Total number of gains: 123; Total number of losses: 61; Total Number of normals: 304.
Somatic mutations of MIA:
Generating mutation plots.
Highly correlated genes for MIA:
Showing top 20/429 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIA | LBX1 | 0.749211 | 3 | 0 | 3 |
| MIA | IGH | 0.726698 | 3 | 0 | 3 |
| MIA | C6orf58 | 0.702775 | 5 | 0 | 4 |
| MIA | ZNF449 | 0.702741 | 3 | 0 | 3 |
| MIA | DMBT1 | 0.692176 | 5 | 0 | 5 |
| MIA | SCGB3A1 | 0.691656 | 5 | 0 | 4 |
| MIA | PROM1 | 0.689264 | 11 | 0 | 10 |
| MIA | CHADL | 0.682173 | 3 | 0 | 3 |
| MIA | HOXD12 | 0.675861 | 3 | 0 | 3 |
| MIA | FIBIN | 0.67349 | 3 | 0 | 3 |
| MIA | SLC6A9 | 0.669138 | 3 | 0 | 3 |
| MIA | LRRD1 | 0.667243 | 3 | 0 | 3 |
| MIA | C11orf16 | 0.666416 | 3 | 0 | 3 |
| MIA | CDO1 | 0.662863 | 8 | 0 | 7 |
| MIA | PPP1R1B | 0.659964 | 6 | 0 | 5 |
| MIA | QPCTL | 0.657896 | 3 | 0 | 3 |
| MIA | ING4 | 0.656256 | 5 | 0 | 5 |
| MIA | HFE | 0.655805 | 4 | 0 | 4 |
| MIA | SMTNL2 | 0.651692 | 5 | 0 | 3 |
| MIA | RNASE4 | 0.650941 | 4 | 0 | 3 |
For details and further investigation, click here
