| Full name: inhibitor of growth family member 4 | Alias Symbol: p29ING4|my036 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 51147 | HGNC ID: HGNC:19423 | Ensembl Gene: ENSG00000111653 | OMIM ID: 608524 |
| Drug and gene relationship at DGIdb | |||
Expression of ING4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ING4 | 51147 | 218234_at | -0.1997 | 0.6858 | |
| GSE20347 | ING4 | 51147 | 48825_at | 0.0619 | 0.7556 | |
| GSE23400 | ING4 | 51147 | 218234_at | 0.0220 | 0.5884 | |
| GSE26886 | ING4 | 51147 | 48825_at | -0.4308 | 0.0540 | |
| GSE29001 | ING4 | 51147 | 48825_at | 0.1423 | 0.5584 | |
| GSE38129 | ING4 | 51147 | 48825_at | -0.0873 | 0.5262 | |
| GSE45670 | ING4 | 51147 | 48825_at | -0.1567 | 0.3004 | |
| GSE53622 | ING4 | 51147 | 6583 | 0.0882 | 0.4225 | |
| GSE53624 | ING4 | 51147 | 6583 | -0.0160 | 0.8757 | |
| GSE63941 | ING4 | 51147 | 218234_at | 0.3443 | 0.4528 | |
| GSE77861 | ING4 | 51147 | 218234_at | -0.0835 | 0.5201 | |
| GSE97050 | ING4 | 51147 | A_23_P48070 | -0.4045 | 0.1581 | |
| SRP007169 | ING4 | 51147 | RNAseq | -0.6499 | 0.1485 | |
| SRP008496 | ING4 | 51147 | RNAseq | -0.0612 | 0.8371 | |
| SRP064894 | ING4 | 51147 | RNAseq | -0.1111 | 0.6291 | |
| SRP133303 | ING4 | 51147 | RNAseq | -0.1352 | 0.5783 | |
| SRP159526 | ING4 | 51147 | RNAseq | -0.2850 | 0.3326 | |
| SRP193095 | ING4 | 51147 | RNAseq | -0.3327 | 0.0126 | |
| SRP219564 | ING4 | 51147 | RNAseq | -0.2096 | 0.5393 | |
| TCGA | ING4 | 51147 | RNAseq | -0.0718 | 0.3331 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ING4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ING4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ING4 | 51147 | 9 | 3 | 18 | |
| GSE20123 | ING4 | 51147 | 9 | 3 | 18 | |
| GSE43470 | ING4 | 51147 | 8 | 3 | 32 | |
| GSE46452 | ING4 | 51147 | 10 | 1 | 48 | |
| GSE47630 | ING4 | 51147 | 12 | 2 | 26 | |
| GSE54993 | ING4 | 51147 | 1 | 10 | 59 | |
| GSE54994 | ING4 | 51147 | 10 | 2 | 41 | |
| GSE60625 | ING4 | 51147 | 0 | 1 | 10 | |
| GSE74703 | ING4 | 51147 | 7 | 2 | 27 | |
| GSE74704 | ING4 | 51147 | 5 | 2 | 13 | |
| TCGA | ING4 | 51147 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 35; Total Number of normals: 342.
Somatic mutations of ING4:
Generating mutation plots.
Highly correlated genes for ING4:
Showing top 20/339 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ING4 | ASB8 | 0.84795 | 3 | 0 | 3 |
| ING4 | SP1 | 0.844582 | 3 | 0 | 3 |
| ING4 | TSPAN3 | 0.792101 | 3 | 0 | 3 |
| ING4 | NUDT16 | 0.782776 | 3 | 0 | 3 |
| ING4 | PEPD | 0.781007 | 3 | 0 | 3 |
| ING4 | KBTBD4 | 0.76087 | 3 | 0 | 3 |
| ING4 | TMEM205 | 0.760091 | 3 | 0 | 3 |
| ING4 | EPS8 | 0.754527 | 3 | 0 | 3 |
| ING4 | CDC26 | 0.753849 | 3 | 0 | 3 |
| ING4 | DLG3 | 0.753011 | 3 | 0 | 3 |
| ING4 | PIN1 | 0.746172 | 3 | 0 | 3 |
| ING4 | PRKAB1 | 0.740688 | 3 | 0 | 3 |
| ING4 | WEE1 | 0.732929 | 3 | 0 | 3 |
| ING4 | FAM76B | 0.730569 | 3 | 0 | 3 |
| ING4 | MRI1 | 0.724474 | 3 | 0 | 3 |
| ING4 | NHS | 0.721028 | 3 | 0 | 3 |
| ING4 | PRKAG2 | 0.718417 | 3 | 0 | 3 |
| ING4 | TMEM80 | 0.713177 | 3 | 0 | 3 |
| ING4 | KRAS | 0.712718 | 4 | 0 | 3 |
| ING4 | MYOCD | 0.712108 | 3 | 0 | 3 |
For details and further investigation, click here
