| Full name: deleted in malignant brain tumors 1 | Alias Symbol: GP340|muclin|SALSA|Gp-340|hensin|vomeroglandin | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 1755 | HGNC ID: HGNC:2926 | Ensembl Gene: ENSG00000187908 | OMIM ID: 601969 |
| Drug and gene relationship at DGIdb | |||
Expression of DMBT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMBT1 | 1755 | 208250_s_at | -0.5381 | 0.4317 | |
| GSE20347 | DMBT1 | 1755 | 208250_s_at | -0.1858 | 0.1241 | |
| GSE23400 | DMBT1 | 1755 | 208250_s_at | -0.3545 | 0.0000 | |
| GSE26886 | DMBT1 | 1755 | 208250_s_at | 0.0629 | 0.7556 | |
| GSE29001 | DMBT1 | 1755 | 208250_s_at | -0.0633 | 0.7767 | |
| GSE38129 | DMBT1 | 1755 | 208250_s_at | -0.2976 | 0.0025 | |
| GSE45670 | DMBT1 | 1755 | 208250_s_at | -0.2647 | 0.0645 | |
| GSE53622 | DMBT1 | 1755 | 6357 | -0.9907 | 0.0021 | |
| GSE53624 | DMBT1 | 1755 | 82209 | -2.5385 | 0.0000 | |
| GSE63941 | DMBT1 | 1755 | 208250_s_at | 0.0710 | 0.7278 | |
| GSE77861 | DMBT1 | 1755 | 208250_s_at | -0.0694 | 0.5776 | |
| GSE97050 | DMBT1 | 1755 | A_33_P3300312 | 0.7456 | 0.2433 | |
| SRP133303 | DMBT1 | 1755 | RNAseq | -4.8977 | 0.0000 | |
| TCGA | DMBT1 | 1755 | RNAseq | -0.6878 | 0.3124 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by DMBT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMBT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMBT1 | 1755 | 1 | 6 | 23 | |
| GSE20123 | DMBT1 | 1755 | 1 | 6 | 23 | |
| GSE43470 | DMBT1 | 1755 | 0 | 9 | 34 | |
| GSE46452 | DMBT1 | 1755 | 0 | 11 | 48 | |
| GSE47630 | DMBT1 | 1755 | 2 | 14 | 24 | |
| GSE54993 | DMBT1 | 1755 | 8 | 1 | 61 | |
| GSE54994 | DMBT1 | 1755 | 1 | 9 | 43 | |
| GSE60625 | DMBT1 | 1755 | 0 | 0 | 11 | |
| GSE74703 | DMBT1 | 1755 | 0 | 6 | 30 | |
| GSE74704 | DMBT1 | 1755 | 1 | 2 | 17 | |
| TCGA | DMBT1 | 1755 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 92; Total Number of normals: 378.
Somatic mutations of DMBT1:
Generating mutation plots.
Highly correlated genes for DMBT1:
Showing top 20/592 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMBT1 | CCL11 | 0.745639 | 3 | 0 | 3 |
| DMBT1 | C6orf58 | 0.736871 | 5 | 0 | 5 |
| DMBT1 | BPIFB1 | 0.729436 | 7 | 0 | 6 |
| DMBT1 | INPP5D | 0.715898 | 3 | 0 | 3 |
| DMBT1 | SAMD15 | 0.711994 | 3 | 0 | 3 |
| DMBT1 | EBF3 | 0.706599 | 3 | 0 | 3 |
| DMBT1 | SCGB3A1 | 0.705444 | 7 | 0 | 6 |
| DMBT1 | GAP43 | 0.704507 | 4 | 0 | 3 |
| DMBT1 | SMG6 | 0.704484 | 3 | 0 | 3 |
| DMBT1 | CYP4V2 | 0.697678 | 3 | 0 | 3 |
| DMBT1 | SHB | 0.69757 | 3 | 0 | 3 |
| DMBT1 | SLC28A2 | 0.697029 | 5 | 0 | 5 |
| DMBT1 | MINK1 | 0.696257 | 4 | 0 | 3 |
| DMBT1 | GTF2IRD1 | 0.695358 | 3 | 0 | 3 |
| DMBT1 | SYTL4 | 0.694469 | 3 | 0 | 3 |
| DMBT1 | MIA | 0.692176 | 5 | 0 | 5 |
| DMBT1 | CASKIN2 | 0.686969 | 3 | 0 | 3 |
| DMBT1 | MXD3 | 0.686244 | 4 | 0 | 3 |
| DMBT1 | CLEC16A | 0.68188 | 3 | 0 | 3 |
| DMBT1 | PRKACA | 0.679997 | 3 | 0 | 3 |
For details and further investigation, click here
