| Full name: nuclear receptor subfamily 2 group C member 2 | Alias Symbol: TAK1|TR2R1|hTAK1 | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 7182 | HGNC ID: HGNC:7972 | Ensembl Gene: ENSG00000177463 | OMIM ID: 601426 |
| Drug and gene relationship at DGIdb | |||
Expression of NR2C2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR2C2 | 7182 | 225477_s_at | 0.2893 | 0.3753 | |
| GSE20347 | NR2C2 | 7182 | 206038_s_at | -0.0616 | 0.3885 | |
| GSE23400 | NR2C2 | 7182 | 206038_s_at | -0.1107 | 0.0001 | |
| GSE26886 | NR2C2 | 7182 | 225477_s_at | -0.8122 | 0.0019 | |
| GSE29001 | NR2C2 | 7182 | 206038_s_at | -0.1554 | 0.4001 | |
| GSE38129 | NR2C2 | 7182 | 206038_s_at | -0.0599 | 0.5168 | |
| GSE45670 | NR2C2 | 7182 | 225477_s_at | -0.2509 | 0.0754 | |
| GSE53622 | NR2C2 | 7182 | 24648 | -0.3261 | 0.0000 | |
| GSE53624 | NR2C2 | 7182 | 24648 | -0.0943 | 0.0782 | |
| GSE63941 | NR2C2 | 7182 | 225477_s_at | -0.2590 | 0.5837 | |
| GSE77861 | NR2C2 | 7182 | 225477_s_at | -0.0789 | 0.7868 | |
| GSE97050 | NR2C2 | 7182 | A_23_P40936 | -0.3037 | 0.1782 | |
| SRP007169 | NR2C2 | 7182 | RNAseq | 0.2462 | 0.4634 | |
| SRP008496 | NR2C2 | 7182 | RNAseq | 0.2754 | 0.1675 | |
| SRP064894 | NR2C2 | 7182 | RNAseq | -0.3010 | 0.3674 | |
| SRP133303 | NR2C2 | 7182 | RNAseq | -0.2227 | 0.0082 | |
| SRP159526 | NR2C2 | 7182 | RNAseq | -0.5484 | 0.0004 | |
| SRP193095 | NR2C2 | 7182 | RNAseq | -0.2386 | 0.0017 | |
| SRP219564 | NR2C2 | 7182 | RNAseq | -0.4713 | 0.2486 | |
| TCGA | NR2C2 | 7182 | RNAseq | -0.1720 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NR2C2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR2C2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR2C2 | 7182 | 1 | 19 | 10 | |
| GSE20123 | NR2C2 | 7182 | 1 | 19 | 10 | |
| GSE43470 | NR2C2 | 7182 | 0 | 21 | 22 | |
| GSE46452 | NR2C2 | 7182 | 2 | 17 | 40 | |
| GSE47630 | NR2C2 | 7182 | 2 | 23 | 15 | |
| GSE54993 | NR2C2 | 7182 | 6 | 1 | 63 | |
| GSE54994 | NR2C2 | 7182 | 1 | 32 | 20 | |
| GSE60625 | NR2C2 | 7182 | 5 | 0 | 6 | |
| GSE74703 | NR2C2 | 7182 | 0 | 17 | 19 | |
| GSE74704 | NR2C2 | 7182 | 1 | 12 | 7 | |
| TCGA | NR2C2 | 7182 | 2 | 68 | 26 |
Total number of gains: 21; Total number of losses: 229; Total Number of normals: 238.
Somatic mutations of NR2C2:
Generating mutation plots.
Highly correlated genes for NR2C2:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR2C2 | MSL2 | 0.796622 | 3 | 0 | 3 |
| NR2C2 | ANKRD13C | 0.793431 | 3 | 0 | 3 |
| NR2C2 | ERP27 | 0.788294 | 3 | 0 | 3 |
| NR2C2 | MIER3 | 0.782941 | 3 | 0 | 3 |
| NR2C2 | PCNT | 0.774429 | 3 | 0 | 3 |
| NR2C2 | WSB2 | 0.769816 | 3 | 0 | 3 |
| NR2C2 | HEATR5A | 0.769741 | 3 | 0 | 3 |
| NR2C2 | CUL2 | 0.758243 | 4 | 0 | 3 |
| NR2C2 | NCKAP1 | 0.756365 | 3 | 0 | 3 |
| NR2C2 | NBR1 | 0.754695 | 3 | 0 | 3 |
| NR2C2 | ACSL1 | 0.752183 | 3 | 0 | 3 |
| NR2C2 | FBXL3 | 0.743706 | 4 | 0 | 4 |
| NR2C2 | TBC1D22B | 0.742108 | 3 | 0 | 3 |
| NR2C2 | IREB2 | 0.741331 | 4 | 0 | 4 |
| NR2C2 | RBM7 | 0.738676 | 4 | 0 | 4 |
| NR2C2 | DDX20 | 0.733274 | 3 | 0 | 3 |
| NR2C2 | EXOC6B | 0.731853 | 3 | 0 | 3 |
| NR2C2 | ZNF317 | 0.730759 | 3 | 0 | 3 |
| NR2C2 | UNC119B | 0.727908 | 3 | 0 | 3 |
| NR2C2 | FAM13B | 0.726714 | 5 | 0 | 5 |
For details and further investigation, click here
