| Full name: A-kinase anchoring protein 9 | Alias Symbol: KIAA0803|AKAP350|AKAP450|CG-NAP|YOTIAO|HYPERION|PRKA9|MU-RMS-40.16A|PPP1R45|LQT11 | ||
| Type: protein-coding gene | Cytoband: 7q21.2 | ||
| Entrez ID: 10142 | HGNC ID: HGNC:379 | Ensembl Gene: ENSG00000127914 | OMIM ID: 604001 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AKAP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKAP9 | 10142 | 210962_s_at | -0.5776 | 0.1369 | |
| GSE20347 | AKAP9 | 10142 | 210962_s_at | -0.6249 | 0.0047 | |
| GSE23400 | AKAP9 | 10142 | 210962_s_at | -0.4883 | 0.0000 | |
| GSE26886 | AKAP9 | 10142 | 210962_s_at | -0.4019 | 0.0477 | |
| GSE29001 | AKAP9 | 10142 | 210962_s_at | -0.6148 | 0.0395 | |
| GSE38129 | AKAP9 | 10142 | 210962_s_at | -0.4147 | 0.0080 | |
| GSE45670 | AKAP9 | 10142 | 210962_s_at | -0.3018 | 0.0842 | |
| GSE53622 | AKAP9 | 10142 | 158576 | -0.3103 | 0.0001 | |
| GSE53624 | AKAP9 | 10142 | 158576 | -0.4329 | 0.0000 | |
| GSE63941 | AKAP9 | 10142 | 210962_s_at | -0.6012 | 0.4892 | |
| GSE77861 | AKAP9 | 10142 | 210962_s_at | -0.5086 | 0.1462 | |
| GSE97050 | AKAP9 | 10142 | A_33_P3380211 | -0.7462 | 0.0672 | |
| SRP007169 | AKAP9 | 10142 | RNAseq | 0.1429 | 0.7056 | |
| SRP008496 | AKAP9 | 10142 | RNAseq | 0.5350 | 0.0381 | |
| SRP064894 | AKAP9 | 10142 | RNAseq | -0.8931 | 0.0005 | |
| SRP133303 | AKAP9 | 10142 | RNAseq | 0.1470 | 0.3794 | |
| SRP159526 | AKAP9 | 10142 | RNAseq | -0.5711 | 0.0813 | |
| SRP193095 | AKAP9 | 10142 | RNAseq | -0.1502 | 0.3503 | |
| SRP219564 | AKAP9 | 10142 | RNAseq | -0.4003 | 0.4576 | |
| TCGA | AKAP9 | 10142 | RNAseq | -0.1662 | 0.0190 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AKAP9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKAP9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKAP9 | 10142 | 13 | 0 | 17 | |
| GSE20123 | AKAP9 | 10142 | 13 | 0 | 17 | |
| GSE43470 | AKAP9 | 10142 | 6 | 1 | 36 | |
| GSE46452 | AKAP9 | 10142 | 11 | 0 | 48 | |
| GSE47630 | AKAP9 | 10142 | 9 | 2 | 29 | |
| GSE54993 | AKAP9 | 10142 | 1 | 8 | 61 | |
| GSE54994 | AKAP9 | 10142 | 16 | 2 | 35 | |
| GSE60625 | AKAP9 | 10142 | 0 | 0 | 11 | |
| GSE74703 | AKAP9 | 10142 | 5 | 1 | 30 | |
| GSE74704 | AKAP9 | 10142 | 9 | 0 | 11 | |
| TCGA | AKAP9 | 10142 | 56 | 4 | 36 |
Total number of gains: 139; Total number of losses: 18; Total Number of normals: 331.
Somatic mutations of AKAP9:
Generating mutation plots.
Highly correlated genes for AKAP9:
Showing top 20/797 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKAP9 | USP33 | 0.784102 | 3 | 0 | 3 |
| AKAP9 | IMPACT | 0.77104 | 3 | 0 | 3 |
| AKAP9 | HDHD2 | 0.769274 | 3 | 0 | 3 |
| AKAP9 | ANKHD1 | 0.742289 | 3 | 0 | 3 |
| AKAP9 | ZRANB1 | 0.738441 | 4 | 0 | 4 |
| AKAP9 | NDUFV2 | 0.737576 | 3 | 0 | 3 |
| AKAP9 | AP3M1 | 0.737039 | 4 | 0 | 4 |
| AKAP9 | MIER3 | 0.733961 | 3 | 0 | 3 |
| AKAP9 | NDST2 | 0.724148 | 3 | 0 | 3 |
| AKAP9 | AK3 | 0.719946 | 5 | 0 | 4 |
| AKAP9 | BRK1 | 0.711271 | 4 | 0 | 4 |
| AKAP9 | KIF13B | 0.710523 | 4 | 0 | 3 |
| AKAP9 | ATG2B | 0.708908 | 3 | 0 | 3 |
| AKAP9 | ANKRD13C | 0.708534 | 3 | 0 | 3 |
| AKAP9 | EPG5 | 0.707698 | 4 | 0 | 4 |
| AKAP9 | NTAN1 | 0.70631 | 3 | 0 | 3 |
| AKAP9 | VDAC2 | 0.704048 | 4 | 0 | 4 |
| AKAP9 | KDM3A | 0.703249 | 4 | 0 | 4 |
| AKAP9 | TPRG1L | 0.702897 | 3 | 0 | 3 |
| AKAP9 | FBXO8 | 0.698002 | 5 | 0 | 4 |
For details and further investigation, click here
