| Full name: galactose-3-O-sulfotransferase 1 | Alias Symbol: CST | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 9514 | HGNC ID: HGNC:24240 | Ensembl Gene: ENSG00000128242 | OMIM ID: 602300 |
| Drug and gene relationship at DGIdb | |||
Expression of GAL3ST1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GAL3ST1 | 9514 | 205670_at | -0.1381 | 0.6054 | |
| GSE20347 | GAL3ST1 | 9514 | 205670_at | 0.0243 | 0.8002 | |
| GSE23400 | GAL3ST1 | 9514 | 205670_at | -0.2022 | 0.0000 | |
| GSE26886 | GAL3ST1 | 9514 | 205670_at | 0.3419 | 0.0309 | |
| GSE29001 | GAL3ST1 | 9514 | 205670_at | -0.1170 | 0.3801 | |
| GSE38129 | GAL3ST1 | 9514 | 205670_at | -0.1409 | 0.0837 | |
| GSE45670 | GAL3ST1 | 9514 | 205670_at | -0.0600 | 0.5486 | |
| GSE53622 | GAL3ST1 | 9514 | 97 | -0.4957 | 0.0039 | |
| GSE53624 | GAL3ST1 | 9514 | 97 | -0.7856 | 0.0000 | |
| GSE63941 | GAL3ST1 | 9514 | 205670_at | 0.0858 | 0.8308 | |
| GSE77861 | GAL3ST1 | 9514 | 205670_at | 0.0129 | 0.9403 | |
| TCGA | GAL3ST1 | 9514 | RNAseq | -2.8177 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GAL3ST1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GAL3ST1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GAL3ST1 | 9514 | 4 | 5 | 21 | |
| GSE20123 | GAL3ST1 | 9514 | 4 | 4 | 22 | |
| GSE43470 | GAL3ST1 | 9514 | 4 | 5 | 34 | |
| GSE46452 | GAL3ST1 | 9514 | 31 | 1 | 27 | |
| GSE47630 | GAL3ST1 | 9514 | 8 | 5 | 27 | |
| GSE54993 | GAL3ST1 | 9514 | 3 | 6 | 61 | |
| GSE54994 | GAL3ST1 | 9514 | 11 | 8 | 34 | |
| GSE60625 | GAL3ST1 | 9514 | 5 | 0 | 6 | |
| GSE74703 | GAL3ST1 | 9514 | 4 | 5 | 27 | |
| GSE74704 | GAL3ST1 | 9514 | 1 | 1 | 18 | |
| TCGA | GAL3ST1 | 9514 | 27 | 15 | 54 |
Total number of gains: 102; Total number of losses: 55; Total Number of normals: 331.
Somatic mutations of GAL3ST1:
Generating mutation plots.
Highly correlated genes for GAL3ST1:
Showing top 20/428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GAL3ST1 | HMCN2 | 0.757374 | 3 | 0 | 3 |
| GAL3ST1 | PPP1R12C | 0.718082 | 3 | 0 | 3 |
| GAL3ST1 | MIOX | 0.693997 | 3 | 0 | 3 |
| GAL3ST1 | EBF4 | 0.692748 | 3 | 0 | 3 |
| GAL3ST1 | FOXD2 | 0.686804 | 3 | 0 | 3 |
| GAL3ST1 | AIRE | 0.683886 | 4 | 0 | 4 |
| GAL3ST1 | TMEM255B | 0.681911 | 3 | 0 | 3 |
| GAL3ST1 | DMRTA1 | 0.673795 | 3 | 0 | 3 |
| GAL3ST1 | VGF | 0.66251 | 4 | 0 | 4 |
| GAL3ST1 | BCAS4 | 0.660803 | 3 | 0 | 3 |
| GAL3ST1 | SSC5D | 0.657993 | 4 | 0 | 3 |
| GAL3ST1 | SPAG8 | 0.654603 | 4 | 0 | 3 |
| GAL3ST1 | C1QTNF3 | 0.651528 | 3 | 0 | 3 |
| GAL3ST1 | EXOC3L1 | 0.644702 | 3 | 0 | 3 |
| GAL3ST1 | SLC13A3 | 0.64324 | 5 | 0 | 5 |
| GAL3ST1 | KRT12 | 0.643125 | 3 | 0 | 3 |
| GAL3ST1 | ULK4 | 0.641079 | 4 | 0 | 3 |
| GAL3ST1 | WFDC3 | 0.639554 | 3 | 0 | 3 |
| GAL3ST1 | CAPN11 | 0.639076 | 3 | 0 | 3 |
| GAL3ST1 | FSHB | 0.638338 | 4 | 0 | 3 |
For details and further investigation, click here
