| Full name: ERH mRNA splicing and mitosis factor | Alias Symbol: DROER | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 2079 | HGNC ID: HGNC:3447 | Ensembl Gene: ENSG00000100632 | OMIM ID: 601191 |
| Drug and gene relationship at DGIdb | |||
Expression of ERH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERH | 2079 | 200043_at | 0.6653 | 0.0286 | |
| GSE20347 | ERH | 2079 | 200043_at | 0.6584 | 0.0000 | |
| GSE23400 | ERH | 2079 | 200043_at | 0.7254 | 0.0000 | |
| GSE26886 | ERH | 2079 | 200043_at | -0.1965 | 0.3936 | |
| GSE29001 | ERH | 2079 | 200043_at | 0.5851 | 0.0018 | |
| GSE38129 | ERH | 2079 | 200043_at | 0.6353 | 0.0000 | |
| GSE45670 | ERH | 2079 | 200043_at | 0.4570 | 0.0007 | |
| GSE53622 | ERH | 2079 | 4814 | 0.4669 | 0.0000 | |
| GSE53624 | ERH | 2079 | 4814 | 0.5863 | 0.0000 | |
| GSE63941 | ERH | 2079 | 200043_at | 0.6032 | 0.0033 | |
| GSE77861 | ERH | 2079 | 200043_at | 0.5285 | 0.0860 | |
| GSE97050 | ERH | 2079 | A_23_P128734 | 0.3804 | 0.2371 | |
| SRP007169 | ERH | 2079 | RNAseq | 0.2749 | 0.3842 | |
| SRP008496 | ERH | 2079 | RNAseq | 0.3645 | 0.0775 | |
| SRP064894 | ERH | 2079 | RNAseq | 0.6214 | 0.0007 | |
| SRP133303 | ERH | 2079 | RNAseq | 0.8217 | 0.0000 | |
| SRP159526 | ERH | 2079 | RNAseq | 0.7290 | 0.0367 | |
| SRP193095 | ERH | 2079 | RNAseq | 0.2361 | 0.1438 | |
| SRP219564 | ERH | 2079 | RNAseq | 0.6325 | 0.1027 | |
| TCGA | ERH | 2079 | RNAseq | 0.3301 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ERH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERH | 2079 | 8 | 3 | 19 | |
| GSE20123 | ERH | 2079 | 8 | 3 | 19 | |
| GSE43470 | ERH | 2079 | 8 | 3 | 32 | |
| GSE46452 | ERH | 2079 | 16 | 3 | 40 | |
| GSE47630 | ERH | 2079 | 11 | 9 | 20 | |
| GSE54993 | ERH | 2079 | 3 | 9 | 58 | |
| GSE54994 | ERH | 2079 | 18 | 5 | 30 | |
| GSE60625 | ERH | 2079 | 0 | 2 | 9 | |
| GSE74703 | ERH | 2079 | 7 | 3 | 26 | |
| GSE74704 | ERH | 2079 | 3 | 3 | 14 | |
| TCGA | ERH | 2079 | 32 | 16 | 48 |
Total number of gains: 114; Total number of losses: 59; Total Number of normals: 315.
Somatic mutations of ERH:
Generating mutation plots.
Highly correlated genes for ERH:
Showing top 20/1656 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERH | SLC39A3 | 0.800538 | 3 | 0 | 3 |
| ERH | CENPBD1 | 0.783279 | 3 | 0 | 3 |
| ERH | CCDC85C | 0.77944 | 3 | 0 | 3 |
| ERH | NUDCD1 | 0.771008 | 5 | 0 | 5 |
| ERH | SERPINH1 | 0.768223 | 9 | 0 | 9 |
| ERH | TMED8 | 0.763385 | 6 | 0 | 6 |
| ERH | KRTCAP2 | 0.757236 | 4 | 0 | 4 |
| ERH | CDKN3 | 0.75676 | 12 | 0 | 12 |
| ERH | SLC25A32 | 0.755937 | 9 | 0 | 9 |
| ERH | PGM2L1 | 0.752756 | 4 | 0 | 4 |
| ERH | MNAT1 | 0.751556 | 12 | 0 | 12 |
| ERH | CD276 | 0.749198 | 3 | 0 | 3 |
| ERH | LSM14B | 0.748713 | 3 | 0 | 3 |
| ERH | SLC38A6 | 0.746318 | 9 | 0 | 8 |
| ERH | VRK1 | 0.745959 | 12 | 0 | 11 |
| ERH | LPCAT1 | 0.744677 | 10 | 0 | 10 |
| ERH | NASP | 0.735733 | 11 | 0 | 11 |
| ERH | HMGB3 | 0.734723 | 11 | 0 | 11 |
| ERH | SUPT16H | 0.733583 | 13 | 0 | 11 |
| ERH | SFMBT1 | 0.730821 | 3 | 0 | 3 |
For details and further investigation, click here
