| Full name: metallophosphoesterase domain containing 1 | Alias Symbol: 239AB|FAM1A | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 758 | HGNC ID: HGNC:1306 | Ensembl Gene: ENSG00000186732 | OMIM ID: 602112 |
| Drug and gene relationship at DGIdb | |||
Expression of MPPED1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPPED1 | 758 | 206436_at | 0.3518 | 0.5995 | |
| GSE20347 | MPPED1 | 758 | 206436_at | 0.1536 | 0.1194 | |
| GSE23400 | MPPED1 | 758 | 206436_at | -0.0471 | 0.2859 | |
| GSE26886 | MPPED1 | 758 | 206436_at | 0.3293 | 0.0083 | |
| GSE29001 | MPPED1 | 758 | 206436_at | -0.0744 | 0.6789 | |
| GSE38129 | MPPED1 | 758 | 206436_at | 0.1826 | 0.0792 | |
| GSE45670 | MPPED1 | 758 | 206436_at | 0.3293 | 0.1884 | |
| GSE53622 | MPPED1 | 758 | 84886 | 0.2319 | 0.0156 | |
| GSE53624 | MPPED1 | 758 | 84886 | 0.0089 | 0.9338 | |
| GSE63941 | MPPED1 | 758 | 206436_at | 0.1668 | 0.3958 | |
| GSE77861 | MPPED1 | 758 | 206436_at | 0.1394 | 0.5557 | |
| GSE97050 | MPPED1 | 758 | A_23_P146855 | -0.2126 | 0.4964 | |
| SRP159526 | MPPED1 | 758 | RNAseq | 5.5067 | 0.0000 | |
| TCGA | MPPED1 | 758 | RNAseq | 0.3574 | 0.6700 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MPPED1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPPED1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPPED1 | 758 | 5 | 7 | 18 | |
| GSE20123 | MPPED1 | 758 | 5 | 6 | 19 | |
| GSE43470 | MPPED1 | 758 | 3 | 6 | 34 | |
| GSE46452 | MPPED1 | 758 | 31 | 2 | 26 | |
| GSE47630 | MPPED1 | 758 | 9 | 4 | 27 | |
| GSE54993 | MPPED1 | 758 | 3 | 6 | 61 | |
| GSE54994 | MPPED1 | 758 | 11 | 8 | 34 | |
| GSE60625 | MPPED1 | 758 | 5 | 0 | 6 | |
| GSE74703 | MPPED1 | 758 | 3 | 4 | 29 | |
| GSE74704 | MPPED1 | 758 | 2 | 3 | 15 | |
| TCGA | MPPED1 | 758 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of MPPED1:
Generating mutation plots.
Highly correlated genes for MPPED1:
Showing top 20/525 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPPED1 | DCDC1 | 0.810854 | 3 | 0 | 3 |
| MPPED1 | KRTAP10-12 | 0.787847 | 3 | 0 | 3 |
| MPPED1 | SOX2-OT | 0.759883 | 3 | 0 | 3 |
| MPPED1 | PLA2G2C | 0.74854 | 3 | 0 | 3 |
| MPPED1 | DEFB121 | 0.737906 | 3 | 0 | 3 |
| MPPED1 | KCNQ1OT1 | 0.732631 | 3 | 0 | 3 |
| MPPED1 | BBC3 | 0.728936 | 3 | 0 | 3 |
| MPPED1 | YY2 | 0.725738 | 3 | 0 | 3 |
| MPPED1 | SPACA3 | 0.720292 | 3 | 0 | 3 |
| MPPED1 | C5orf17 | 0.718805 | 3 | 0 | 3 |
| MPPED1 | STRC | 0.717034 | 3 | 0 | 3 |
| MPPED1 | CASC15 | 0.712862 | 6 | 0 | 5 |
| MPPED1 | MRPS16 | 0.710664 | 3 | 0 | 3 |
| MPPED1 | CCDC106 | 0.70632 | 4 | 0 | 3 |
| MPPED1 | TOR2A | 0.697131 | 3 | 0 | 3 |
| MPPED1 | TNFAIP8L1 | 0.691933 | 4 | 0 | 4 |
| MPPED1 | TTTY5 | 0.691552 | 3 | 0 | 3 |
| MPPED1 | TCTE3 | 0.690956 | 3 | 0 | 3 |
| MPPED1 | TPH2 | 0.690417 | 4 | 0 | 4 |
| MPPED1 | CELF5 | 0.687938 | 3 | 0 | 3 |
For details and further investigation, click here
