| Full name: SOX2 overlapping transcript | Alias Symbol: DKFZp761J1324|NCRNA00043 | ||
| Type: non-coding RNA | Cytoband: 3q26.33 | ||
| Entrez ID: 347689 | HGNC ID: HGNC:20209 | Ensembl Gene: ENSG00000242808 | OMIM ID: 616338 |
| Drug and gene relationship at DGIdb | |||
Expression of SOX2-OT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOX2-OT | 347689 | 231898_x_at | 0.5191 | 0.5849 | |
| GSE26886 | SOX2-OT | 347689 | 231898_x_at | 1.3772 | 0.0514 | |
| GSE45670 | SOX2-OT | 347689 | 231898_x_at | 0.5626 | 0.3133 | |
| GSE53622 | SOX2-OT | 347689 | 152166 | 1.0096 | 0.0001 | |
| GSE53624 | SOX2-OT | 347689 | 14028 | 1.0771 | 0.0000 | |
| GSE63941 | SOX2-OT | 347689 | 231898_x_at | 1.7181 | 0.3967 | |
| GSE77861 | SOX2-OT | 347689 | 231898_x_at | 0.2186 | 0.0734 | |
| SRP007169 | SOX2-OT | 347689 | RNAseq | 5.5605 | 0.0000 | |
| SRP064894 | SOX2-OT | 347689 | RNAseq | 1.2967 | 0.0004 | |
| SRP133303 | SOX2-OT | 347689 | RNAseq | -0.0107 | 0.9696 | |
| SRP159526 | SOX2-OT | 347689 | RNAseq | 3.7287 | 0.0000 | |
| SRP193095 | SOX2-OT | 347689 | RNAseq | 1.1856 | 0.0000 | |
| SRP219564 | SOX2-OT | 347689 | RNAseq | 0.3265 | 0.5041 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SOX2-OT expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SOX2-OT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOX2-OT | 347689 | 26 | 0 | 4 | |
| GSE20123 | SOX2-OT | 347689 | 26 | 0 | 4 | |
| GSE43470 | SOX2-OT | 347689 | 24 | 0 | 19 | |
| GSE46452 | SOX2-OT | 347689 | 19 | 1 | 39 | |
| GSE47630 | SOX2-OT | 347689 | 27 | 2 | 11 | |
| GSE54993 | SOX2-OT | 347689 | 1 | 18 | 51 | |
| GSE54994 | SOX2-OT | 347689 | 41 | 0 | 12 | |
| GSE60625 | SOX2-OT | 347689 | 0 | 6 | 5 | |
| GSE74703 | SOX2-OT | 347689 | 20 | 0 | 16 | |
| GSE74704 | SOX2-OT | 347689 | 17 | 0 | 3 |
Total number of gains: 201; Total number of losses: 27; Total Number of normals: 164.
Somatic mutations of SOX2-OT:
Generating mutation plots.
Highly correlated genes for SOX2-OT:
Showing top 20/203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOX2-OT | MPPED1 | 0.759883 | 3 | 0 | 3 |
| SOX2-OT | CYP26A1 | 0.75604 | 6 | 0 | 6 |
| SOX2-OT | TMEM116 | 0.711601 | 5 | 0 | 5 |
| SOX2-OT | MIAT | 0.706901 | 3 | 0 | 3 |
| SOX2-OT | JAKMIP3 | 0.701861 | 4 | 0 | 3 |
| SOX2-OT | BDNF | 0.697843 | 4 | 0 | 3 |
| SOX2-OT | C6orf15 | 0.693995 | 3 | 0 | 3 |
| SOX2-OT | NTRK2 | 0.693946 | 7 | 0 | 7 |
| SOX2-OT | CHST7 | 0.687945 | 6 | 0 | 6 |
| SOX2-OT | KCNE3 | 0.67864 | 4 | 0 | 4 |
| SOX2-OT | SOSTDC1 | 0.675019 | 4 | 0 | 4 |
| SOX2-OT | LINC01139 | 0.670471 | 4 | 0 | 4 |
| SOX2-OT | MRAP2 | 0.665672 | 6 | 0 | 5 |
| SOX2-OT | KIAA1324 | 0.664664 | 4 | 0 | 3 |
| SOX2-OT | ADAM23 | 0.66417 | 5 | 0 | 4 |
| SOX2-OT | DMRT2 | 0.663075 | 7 | 0 | 6 |
| SOX2-OT | ABCC5 | 0.661605 | 6 | 0 | 6 |
| SOX2-OT | TXNRD1 | 0.656399 | 6 | 0 | 5 |
| SOX2-OT | GPC3 | 0.654456 | 7 | 0 | 6 |
| SOX2-OT | CCDC177 | 0.654201 | 5 | 0 | 5 |
For details and further investigation, click here
