| Full name: GA binding protein transcription factor subunit beta 1 | Alias Symbol: E4TF1-47|GABPB | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 2553 | HGNC ID: HGNC:4074 | Ensembl Gene: ENSG00000104064 | OMIM ID: 600610 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GABPB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GABPB1 | 2553 | 204618_s_at | 0.6622 | 0.1465 | |
| GSE20347 | GABPB1 | 2553 | 204618_s_at | 0.6381 | 0.0003 | |
| GSE23400 | GABPB1 | 2553 | 204618_s_at | 0.4383 | 0.0000 | |
| GSE26886 | GABPB1 | 2553 | 204618_s_at | -0.7136 | 0.0054 | |
| GSE29001 | GABPB1 | 2553 | 204618_s_at | 0.4583 | 0.0231 | |
| GSE38129 | GABPB1 | 2553 | 204618_s_at | 0.7834 | 0.0000 | |
| GSE45670 | GABPB1 | 2553 | 204618_s_at | 0.3142 | 0.0511 | |
| GSE53622 | GABPB1 | 2553 | 106536 | 0.6631 | 0.0000 | |
| GSE53624 | GABPB1 | 2553 | 64262 | 0.9187 | 0.0000 | |
| GSE63941 | GABPB1 | 2553 | 204618_s_at | -0.1495 | 0.7343 | |
| GSE77861 | GABPB1 | 2553 | 204618_s_at | 0.5100 | 0.0213 | |
| GSE97050 | GABPB1 | 2553 | A_23_P205789 | 0.6343 | 0.1623 | |
| SRP007169 | GABPB1 | 2553 | RNAseq | 0.1490 | 0.7341 | |
| SRP008496 | GABPB1 | 2553 | RNAseq | 0.2297 | 0.4143 | |
| SRP064894 | GABPB1 | 2553 | RNAseq | 0.2541 | 0.2055 | |
| SRP133303 | GABPB1 | 2553 | RNAseq | 0.9352 | 0.0000 | |
| SRP159526 | GABPB1 | 2553 | RNAseq | 0.4137 | 0.1762 | |
| SRP193095 | GABPB1 | 2553 | RNAseq | 0.5037 | 0.0000 | |
| SRP219564 | GABPB1 | 2553 | RNAseq | 0.7265 | 0.0449 | |
| TCGA | GABPB1 | 2553 | RNAseq | 0.2468 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GABPB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GABPB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GABPB1 | 2553 | 5 | 3 | 22 | |
| GSE20123 | GABPB1 | 2553 | 5 | 3 | 22 | |
| GSE43470 | GABPB1 | 2553 | 5 | 4 | 34 | |
| GSE46452 | GABPB1 | 2553 | 3 | 7 | 49 | |
| GSE47630 | GABPB1 | 2553 | 8 | 10 | 22 | |
| GSE54993 | GABPB1 | 2553 | 4 | 6 | 60 | |
| GSE54994 | GABPB1 | 2553 | 5 | 7 | 41 | |
| GSE60625 | GABPB1 | 2553 | 4 | 0 | 7 | |
| GSE74703 | GABPB1 | 2553 | 5 | 3 | 28 | |
| GSE74704 | GABPB1 | 2553 | 2 | 3 | 15 | |
| TCGA | GABPB1 | 2553 | 9 | 16 | 71 |
Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.
Somatic mutations of GABPB1:
Generating mutation plots.
Highly correlated genes for GABPB1:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GABPB1 | C8orf76 | 0.772244 | 3 | 0 | 3 |
| GABPB1 | LAMTOR1 | 0.760999 | 3 | 0 | 3 |
| GABPB1 | UHMK1 | 0.748146 | 4 | 0 | 4 |
| GABPB1 | ARL6IP6 | 0.73051 | 4 | 0 | 4 |
| GABPB1 | CTDSPL2 | 0.72878 | 4 | 0 | 4 |
| GABPB1 | USP34 | 0.707264 | 3 | 0 | 3 |
| GABPB1 | ZNF260 | 0.706755 | 3 | 0 | 3 |
| GABPB1 | DTL | 0.700762 | 10 | 0 | 10 |
| GABPB1 | ALG10 | 0.700138 | 4 | 0 | 4 |
| GABPB1 | MRPL2 | 0.698327 | 3 | 0 | 3 |
| GABPB1 | KBTBD2 | 0.697732 | 6 | 0 | 6 |
| GABPB1 | ANAPC1 | 0.697467 | 3 | 0 | 3 |
| GABPB1 | RCN2 | 0.697319 | 8 | 0 | 7 |
| GABPB1 | DBF4 | 0.695137 | 10 | 0 | 9 |
| GABPB1 | UCK2 | 0.692904 | 3 | 0 | 3 |
| GABPB1 | CCDC117 | 0.692898 | 5 | 0 | 5 |
| GABPB1 | RRP9 | 0.692352 | 4 | 0 | 4 |
| GABPB1 | PYCR2 | 0.690215 | 3 | 0 | 3 |
| GABPB1 | ZFPL1 | 0.68763 | 3 | 0 | 3 |
| GABPB1 | MAD2L1 | 0.687485 | 9 | 0 | 9 |
For details and further investigation, click here
