| Full name: GDNF inducible zinc finger protein 1 | Alias Symbol: dJ322G13.2|ZBTB23 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 64412 | HGNC ID: HGNC:15808 | Ensembl Gene: ENSG00000125812 | OMIM ID: 613842 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GZF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GZF1 | 64412 | 225884_s_at | 0.4952 | 0.4309 | |
| GSE26886 | GZF1 | 64412 | 225884_s_at | 0.4867 | 0.0285 | |
| GSE45670 | GZF1 | 64412 | 225884_s_at | 0.1739 | 0.3440 | |
| GSE53622 | GZF1 | 64412 | 109057 | 0.5523 | 0.0000 | |
| GSE53624 | GZF1 | 64412 | 109057 | 0.4969 | 0.0000 | |
| GSE63941 | GZF1 | 64412 | 225884_s_at | -0.6124 | 0.2810 | |
| GSE77861 | GZF1 | 64412 | 225884_s_at | 0.2508 | 0.3766 | |
| GSE97050 | GZF1 | 64412 | A_33_P3287078 | 0.2772 | 0.4210 | |
| SRP007169 | GZF1 | 64412 | RNAseq | 0.4245 | 0.4303 | |
| SRP008496 | GZF1 | 64412 | RNAseq | 0.9755 | 0.0090 | |
| SRP064894 | GZF1 | 64412 | RNAseq | -0.0073 | 0.9647 | |
| SRP133303 | GZF1 | 64412 | RNAseq | 0.4368 | 0.0004 | |
| SRP159526 | GZF1 | 64412 | RNAseq | 0.2751 | 0.0844 | |
| SRP193095 | GZF1 | 64412 | RNAseq | 0.1629 | 0.1122 | |
| SRP219564 | GZF1 | 64412 | RNAseq | 0.3360 | 0.3808 | |
| TCGA | GZF1 | 64412 | RNAseq | -0.0720 | 0.2422 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GZF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GZF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GZF1 | 64412 | 13 | 1 | 16 | |
| GSE20123 | GZF1 | 64412 | 13 | 1 | 16 | |
| GSE43470 | GZF1 | 64412 | 11 | 1 | 31 | |
| GSE46452 | GZF1 | 64412 | 27 | 1 | 31 | |
| GSE47630 | GZF1 | 64412 | 17 | 4 | 19 | |
| GSE54993 | GZF1 | 64412 | 0 | 17 | 53 | |
| GSE54994 | GZF1 | 64412 | 26 | 2 | 25 | |
| GSE60625 | GZF1 | 64412 | 0 | 0 | 11 | |
| GSE74703 | GZF1 | 64412 | 9 | 1 | 26 | |
| GSE74704 | GZF1 | 64412 | 7 | 1 | 12 | |
| TCGA | GZF1 | 64412 | 42 | 11 | 43 |
Total number of gains: 165; Total number of losses: 40; Total Number of normals: 283.
Somatic mutations of GZF1:
Generating mutation plots.
Highly correlated genes for GZF1:
Showing top 20/608 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GZF1 | GNS | 0.820766 | 3 | 0 | 3 |
| GZF1 | RSPRY1 | 0.791007 | 3 | 0 | 3 |
| GZF1 | ZNF550 | 0.778558 | 3 | 0 | 3 |
| GZF1 | NUDT3 | 0.776491 | 3 | 0 | 3 |
| GZF1 | SLC22A5 | 0.772911 | 3 | 0 | 3 |
| GZF1 | SLC7A6OS | 0.760505 | 3 | 0 | 3 |
| GZF1 | IQCK | 0.759515 | 3 | 0 | 3 |
| GZF1 | FAM160B1 | 0.758773 | 3 | 0 | 3 |
| GZF1 | CDC42EP4 | 0.75845 | 3 | 0 | 3 |
| GZF1 | CPLX1 | 0.756905 | 3 | 0 | 3 |
| GZF1 | FAM168A | 0.750836 | 3 | 0 | 3 |
| GZF1 | MTHFSD | 0.746619 | 3 | 0 | 3 |
| GZF1 | LRRC14 | 0.745775 | 4 | 0 | 3 |
| GZF1 | PTPN4 | 0.741304 | 3 | 0 | 3 |
| GZF1 | TRIM47 | 0.740861 | 3 | 0 | 3 |
| GZF1 | ZZZ3 | 0.740082 | 3 | 0 | 3 |
| GZF1 | PMPCB | 0.739931 | 4 | 0 | 3 |
| GZF1 | COA5 | 0.735318 | 3 | 0 | 3 |
| GZF1 | ZSCAN21 | 0.731535 | 3 | 0 | 3 |
| GZF1 | PITX2 | 0.729502 | 3 | 0 | 3 |
For details and further investigation, click here
