| Full name: formin like 2 | Alias Symbol: KIAA1902 | ||
| Type: protein-coding gene | Cytoband: 2q23.3 | ||
| Entrez ID: 114793 | HGNC ID: HGNC:18267 | Ensembl Gene: ENSG00000157827 | OMIM ID: 616285 |
| Drug and gene relationship at DGIdb | |||
Expression of FMNL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMNL2 | 114793 | 226184_at | 1.4091 | 0.0590 | |
| GSE26886 | FMNL2 | 114793 | 226184_at | 3.3735 | 0.0000 | |
| GSE45670 | FMNL2 | 114793 | 226184_at | 1.0678 | 0.0093 | |
| GSE53622 | FMNL2 | 114793 | 21912 | 1.4932 | 0.0000 | |
| GSE53624 | FMNL2 | 114793 | 21912 | 1.5427 | 0.0000 | |
| GSE63941 | FMNL2 | 114793 | 226184_at | -1.5082 | 0.0306 | |
| GSE77861 | FMNL2 | 114793 | 226184_at | 2.7381 | 0.0005 | |
| GSE97050 | FMNL2 | 114793 | A_32_P193080 | 0.6458 | 0.1403 | |
| SRP007169 | FMNL2 | 114793 | RNAseq | 3.8144 | 0.0000 | |
| SRP008496 | FMNL2 | 114793 | RNAseq | 3.6452 | 0.0000 | |
| SRP064894 | FMNL2 | 114793 | RNAseq | 1.8022 | 0.0000 | |
| SRP133303 | FMNL2 | 114793 | RNAseq | 1.6074 | 0.0000 | |
| SRP159526 | FMNL2 | 114793 | RNAseq | 1.4059 | 0.0000 | |
| SRP193095 | FMNL2 | 114793 | RNAseq | 1.6507 | 0.0000 | |
| SRP219564 | FMNL2 | 114793 | RNAseq | 0.5349 | 0.1012 | |
| TCGA | FMNL2 | 114793 | RNAseq | 0.2107 | 0.0060 |
Upregulated datasets: 11; Downregulated datasets: 1.
Survival by FMNL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMNL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMNL2 | 114793 | 3 | 2 | 25 | |
| GSE20123 | FMNL2 | 114793 | 3 | 2 | 25 | |
| GSE43470 | FMNL2 | 114793 | 3 | 1 | 39 | |
| GSE46452 | FMNL2 | 114793 | 1 | 4 | 54 | |
| GSE47630 | FMNL2 | 114793 | 5 | 3 | 32 | |
| GSE54993 | FMNL2 | 114793 | 0 | 5 | 65 | |
| GSE54994 | FMNL2 | 114793 | 11 | 2 | 40 | |
| GSE60625 | FMNL2 | 114793 | 0 | 3 | 8 | |
| GSE74703 | FMNL2 | 114793 | 2 | 1 | 33 | |
| GSE74704 | FMNL2 | 114793 | 2 | 0 | 18 | |
| TCGA | FMNL2 | 114793 | 21 | 8 | 67 |
Total number of gains: 51; Total number of losses: 31; Total Number of normals: 406.
Somatic mutations of FMNL2:
Generating mutation plots.
Highly correlated genes for FMNL2:
Showing top 20/1892 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMNL2 | LPCAT1 | 0.867226 | 7 | 0 | 7 |
| FMNL2 | C11orf24 | 0.827939 | 7 | 0 | 7 |
| FMNL2 | XPR1 | 0.823602 | 7 | 0 | 7 |
| FMNL2 | SERPINH1 | 0.821606 | 6 | 0 | 6 |
| FMNL2 | MYO10 | 0.820453 | 4 | 0 | 4 |
| FMNL2 | FNDC3B | 0.81924 | 7 | 0 | 7 |
| FMNL2 | MET | 0.810772 | 7 | 0 | 7 |
| FMNL2 | MFAP2 | 0.798835 | 7 | 0 | 7 |
| FMNL2 | LRP12 | 0.795597 | 7 | 0 | 7 |
| FMNL2 | WDR54 | 0.793932 | 7 | 0 | 7 |
| FMNL2 | TRIO | 0.790662 | 7 | 0 | 7 |
| FMNL2 | PFDN2 | 0.790464 | 7 | 0 | 7 |
| FMNL2 | ZNF281 | 0.788266 | 8 | 0 | 8 |
| FMNL2 | PLAU | 0.785893 | 7 | 0 | 7 |
| FMNL2 | STK3 | 0.78494 | 7 | 0 | 6 |
| FMNL2 | PDE7A | 0.783897 | 7 | 0 | 7 |
| FMNL2 | TMEM184B | 0.780939 | 7 | 0 | 7 |
| FMNL2 | FSCN1 | 0.77672 | 7 | 0 | 7 |
| FMNL2 | RTKN | 0.776043 | 7 | 0 | 7 |
| FMNL2 | TGFBI | 0.775785 | 8 | 0 | 8 |
For details and further investigation, click here
