| Full name: mitochondrial ribosomal protein S14 | Alias Symbol: HSMRPS14 | ||
| Type: protein-coding gene | Cytoband: 1q25.1 | ||
| Entrez ID: 63931 | HGNC ID: HGNC:14049 | Ensembl Gene: ENSG00000120333 | OMIM ID: 611978 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS14 | 63931 | 203800_s_at | 0.3238 | 0.0650 | |
| GSE20347 | MRPS14 | 63931 | 203800_s_at | 0.4322 | 0.0096 | |
| GSE23400 | MRPS14 | 63931 | 203800_s_at | 0.2942 | 0.0000 | |
| GSE26886 | MRPS14 | 63931 | 203800_s_at | -0.2019 | 0.2275 | |
| GSE29001 | MRPS14 | 63931 | 203800_s_at | 0.4567 | 0.1881 | |
| GSE38129 | MRPS14 | 63931 | 203800_s_at | 0.5179 | 0.0001 | |
| GSE45670 | MRPS14 | 63931 | 203800_s_at | 0.3882 | 0.0003 | |
| GSE53622 | MRPS14 | 63931 | 12744 | 0.2022 | 0.0005 | |
| GSE53624 | MRPS14 | 63931 | 12744 | 0.4691 | 0.0000 | |
| GSE63941 | MRPS14 | 63931 | 203800_s_at | 0.4491 | 0.0774 | |
| GSE77861 | MRPS14 | 63931 | 203800_s_at | 0.2491 | 0.1073 | |
| GSE97050 | MRPS14 | 63931 | A_23_P62731 | -0.0678 | 0.8489 | |
| SRP007169 | MRPS14 | 63931 | RNAseq | -0.1290 | 0.7322 | |
| SRP008496 | MRPS14 | 63931 | RNAseq | 0.2514 | 0.3675 | |
| SRP064894 | MRPS14 | 63931 | RNAseq | -0.1769 | 0.1540 | |
| SRP133303 | MRPS14 | 63931 | RNAseq | 0.0078 | 0.9606 | |
| SRP159526 | MRPS14 | 63931 | RNAseq | 0.2371 | 0.1987 | |
| SRP193095 | MRPS14 | 63931 | RNAseq | -0.2884 | 0.0069 | |
| SRP219564 | MRPS14 | 63931 | RNAseq | 0.1574 | 0.5251 | |
| TCGA | MRPS14 | 63931 | RNAseq | 0.0390 | 0.5127 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS14 | 63931 | 12 | 0 | 18 | |
| GSE20123 | MRPS14 | 63931 | 12 | 0 | 18 | |
| GSE43470 | MRPS14 | 63931 | 7 | 2 | 34 | |
| GSE46452 | MRPS14 | 63931 | 3 | 1 | 55 | |
| GSE47630 | MRPS14 | 63931 | 14 | 0 | 26 | |
| GSE54993 | MRPS14 | 63931 | 0 | 6 | 64 | |
| GSE54994 | MRPS14 | 63931 | 15 | 0 | 38 | |
| GSE60625 | MRPS14 | 63931 | 0 | 0 | 11 | |
| GSE74703 | MRPS14 | 63931 | 7 | 2 | 27 | |
| GSE74704 | MRPS14 | 63931 | 5 | 0 | 15 | |
| TCGA | MRPS14 | 63931 | 41 | 3 | 52 |
Total number of gains: 116; Total number of losses: 14; Total Number of normals: 358.
Somatic mutations of MRPS14:
Generating mutation plots.
Highly correlated genes for MRPS14:
Showing top 20/1279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS14 | TATDN2 | 0.84846 | 3 | 0 | 3 |
| MRPS14 | MKRN1 | 0.798321 | 3 | 0 | 3 |
| MRPS14 | SLC7A6OS | 0.789109 | 3 | 0 | 3 |
| MRPS14 | MRPL37 | 0.784848 | 3 | 0 | 3 |
| MRPS14 | VPS41 | 0.78463 | 3 | 0 | 3 |
| MRPS14 | SETX | 0.778598 | 3 | 0 | 3 |
| MRPS14 | CXXC1 | 0.772255 | 3 | 0 | 3 |
| MRPS14 | CCDC127 | 0.767038 | 3 | 0 | 3 |
| MRPS14 | STK4 | 0.760385 | 3 | 0 | 3 |
| MRPS14 | RBM22 | 0.760119 | 3 | 0 | 3 |
| MRPS14 | RLIM | 0.753392 | 4 | 0 | 4 |
| MRPS14 | MRPL14 | 0.745015 | 4 | 0 | 4 |
| MRPS14 | SSBP4 | 0.744227 | 3 | 0 | 3 |
| MRPS14 | NFKB1 | 0.741969 | 3 | 0 | 3 |
| MRPS14 | SOX18 | 0.736964 | 3 | 0 | 3 |
| MRPS14 | FH | 0.733646 | 3 | 0 | 3 |
| MRPS14 | NUDCD1 | 0.730112 | 4 | 0 | 4 |
| MRPS14 | UBXN1 | 0.72403 | 3 | 0 | 3 |
| MRPS14 | PHF3 | 0.721967 | 3 | 0 | 3 |
| MRPS14 | SMARCAD1 | 0.721683 | 4 | 0 | 3 |
For details and further investigation, click here
