| Full name: PHD finger protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q12 | ||
| Entrez ID: 23469 | HGNC ID: HGNC:8921 | Ensembl Gene: ENSG00000118482 | OMIM ID: 607789 |
| Drug and gene relationship at DGIdb | |||
Expression of PHF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF3 | 23469 | 217954_s_at | -0.1323 | 0.7401 | |
| GSE20347 | PHF3 | 23469 | 217954_s_at | -0.1079 | 0.4050 | |
| GSE23400 | PHF3 | 23469 | 217954_s_at | 0.3109 | 0.0001 | |
| GSE26886 | PHF3 | 23469 | 217954_s_at | 0.5519 | 0.0258 | |
| GSE29001 | PHF3 | 23469 | 217954_s_at | 0.2598 | 0.3428 | |
| GSE38129 | PHF3 | 23469 | 217954_s_at | -0.1235 | 0.3753 | |
| GSE45670 | PHF3 | 23469 | 217954_s_at | -0.2528 | 0.2230 | |
| GSE53622 | PHF3 | 23469 | 76753 | 0.0232 | 0.7689 | |
| GSE53624 | PHF3 | 23469 | 76753 | 0.0997 | 0.1047 | |
| GSE63941 | PHF3 | 23469 | 217954_s_at | -0.2944 | 0.5676 | |
| GSE77861 | PHF3 | 23469 | 217954_s_at | 0.2783 | 0.5083 | |
| GSE97050 | PHF3 | 23469 | A_23_P70371 | -0.2203 | 0.2764 | |
| SRP007169 | PHF3 | 23469 | RNAseq | 0.8792 | 0.0101 | |
| SRP008496 | PHF3 | 23469 | RNAseq | 0.5154 | 0.0256 | |
| SRP064894 | PHF3 | 23469 | RNAseq | -0.0905 | 0.7227 | |
| SRP133303 | PHF3 | 23469 | RNAseq | 0.0974 | 0.4183 | |
| SRP159526 | PHF3 | 23469 | RNAseq | 0.0590 | 0.7995 | |
| SRP193095 | PHF3 | 23469 | RNAseq | 0.0381 | 0.6764 | |
| SRP219564 | PHF3 | 23469 | RNAseq | 0.3729 | 0.2685 | |
| TCGA | PHF3 | 23469 | RNAseq | -0.0405 | 0.3659 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF3 | 23469 | 1 | 4 | 25 | |
| GSE20123 | PHF3 | 23469 | 1 | 4 | 25 | |
| GSE43470 | PHF3 | 23469 | 6 | 0 | 37 | |
| GSE46452 | PHF3 | 23469 | 3 | 10 | 46 | |
| GSE47630 | PHF3 | 23469 | 8 | 4 | 28 | |
| GSE54993 | PHF3 | 23469 | 3 | 2 | 65 | |
| GSE54994 | PHF3 | 23469 | 11 | 2 | 40 | |
| GSE60625 | PHF3 | 23469 | 0 | 2 | 9 | |
| GSE74703 | PHF3 | 23469 | 6 | 0 | 30 | |
| GSE74704 | PHF3 | 23469 | 0 | 3 | 17 | |
| TCGA | PHF3 | 23469 | 18 | 11 | 67 |
Total number of gains: 57; Total number of losses: 42; Total Number of normals: 389.
Somatic mutations of PHF3:
Generating mutation plots.
Highly correlated genes for PHF3:
Showing top 20/562 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF3 | TTC8 | 0.778001 | 4 | 0 | 4 |
| PHF3 | PFKP | 0.760657 | 3 | 0 | 3 |
| PHF3 | FANCL | 0.756199 | 4 | 0 | 4 |
| PHF3 | BOD1 | 0.743742 | 3 | 0 | 3 |
| PHF3 | ASPH | 0.743655 | 3 | 0 | 3 |
| PHF3 | RNF13 | 0.737075 | 3 | 0 | 3 |
| PHF3 | PMPCB | 0.735627 | 4 | 0 | 3 |
| PHF3 | NEK4 | 0.733501 | 3 | 0 | 3 |
| PHF3 | NPHP3 | 0.73298 | 3 | 0 | 3 |
| PHF3 | GPCPD1 | 0.729669 | 3 | 0 | 3 |
| PHF3 | IGIP | 0.72342 | 3 | 0 | 3 |
| PHF3 | SCAMP1 | 0.723352 | 4 | 0 | 4 |
| PHF3 | MRPS14 | 0.721967 | 3 | 0 | 3 |
| PHF3 | NOC3L | 0.718346 | 4 | 0 | 4 |
| PHF3 | FNIP1 | 0.717199 | 3 | 0 | 3 |
| PHF3 | RFTN1 | 0.705135 | 3 | 0 | 3 |
| PHF3 | ZBTB26 | 0.704225 | 3 | 0 | 3 |
| PHF3 | EML1 | 0.704076 | 3 | 0 | 3 |
| PHF3 | AP3M2 | 0.703728 | 3 | 0 | 3 |
| PHF3 | ZNF766 | 0.695954 | 3 | 0 | 3 |
For details and further investigation, click here
