| Full name: mitochondrial ribosomal protein L14 | Alias Symbol: RPML32|MRP-L32 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 64928 | HGNC ID: HGNC:14279 | Ensembl Gene: ENSG00000180992 | OMIM ID: 611827 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPL14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL14 | 64928 | 225201_s_at | 1.0577 | 0.0136 | |
| GSE26886 | MRPL14 | 64928 | 225201_s_at | 0.8557 | 0.0000 | |
| GSE45670 | MRPL14 | 64928 | 225201_s_at | 0.5632 | 0.0002 | |
| GSE53622 | MRPL14 | 64928 | 28900 | 0.3330 | 0.0005 | |
| GSE53624 | MRPL14 | 64928 | 28900 | 0.8606 | 0.0000 | |
| GSE63941 | MRPL14 | 64928 | 225201_s_at | -0.0351 | 0.9371 | |
| GSE77861 | MRPL14 | 64928 | 225201_s_at | 0.2432 | 0.2928 | |
| GSE97050 | MRPL14 | 64928 | A_33_P3278540 | 0.3922 | 0.2613 | |
| SRP007169 | MRPL14 | 64928 | RNAseq | 0.4312 | 0.3197 | |
| SRP008496 | MRPL14 | 64928 | RNAseq | 0.3489 | 0.2033 | |
| SRP064894 | MRPL14 | 64928 | RNAseq | 1.0732 | 0.0030 | |
| SRP133303 | MRPL14 | 64928 | RNAseq | 0.7025 | 0.0000 | |
| SRP159526 | MRPL14 | 64928 | RNAseq | 0.4620 | 0.0714 | |
| SRP193095 | MRPL14 | 64928 | RNAseq | 0.1513 | 0.3493 | |
| SRP219564 | MRPL14 | 64928 | RNAseq | 0.5858 | 0.1080 | |
| TCGA | MRPL14 | 64928 | RNAseq | 0.2937 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MRPL14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL14 | 64928 | 8 | 0 | 22 | |
| GSE20123 | MRPL14 | 64928 | 8 | 0 | 22 | |
| GSE43470 | MRPL14 | 64928 | 6 | 0 | 37 | |
| GSE46452 | MRPL14 | 64928 | 3 | 9 | 47 | |
| GSE47630 | MRPL14 | 64928 | 8 | 4 | 28 | |
| GSE54993 | MRPL14 | 64928 | 3 | 2 | 65 | |
| GSE54994 | MRPL14 | 64928 | 10 | 4 | 39 | |
| GSE60625 | MRPL14 | 64928 | 0 | 1 | 10 | |
| GSE74703 | MRPL14 | 64928 | 6 | 0 | 30 | |
| GSE74704 | MRPL14 | 64928 | 4 | 0 | 16 | |
| TCGA | MRPL14 | 64928 | 21 | 12 | 63 |
Total number of gains: 77; Total number of losses: 32; Total Number of normals: 379.
Somatic mutations of MRPL14:
Generating mutation plots.
Highly correlated genes for MRPL14:
Showing top 20/1660 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL14 | SLC1A5 | 0.808801 | 3 | 0 | 3 |
| MRPL14 | C1orf112 | 0.803946 | 5 | 0 | 5 |
| MRPL14 | ZNF593 | 0.78539 | 3 | 0 | 3 |
| MRPL14 | RRP36 | 0.784734 | 8 | 0 | 8 |
| MRPL14 | TAF4B | 0.778426 | 3 | 0 | 3 |
| MRPL14 | TMEM132A | 0.773636 | 4 | 0 | 4 |
| MRPL14 | GMNN | 0.767723 | 8 | 0 | 8 |
| MRPL14 | STK3 | 0.759969 | 4 | 0 | 4 |
| MRPL14 | WDR4 | 0.755736 | 5 | 0 | 5 |
| MRPL14 | MAZ | 0.748951 | 3 | 0 | 3 |
| MRPL14 | PPIL1 | 0.745169 | 9 | 0 | 9 |
| MRPL14 | MRPS14 | 0.745015 | 4 | 0 | 4 |
| MRPL14 | CCT6A | 0.743611 | 4 | 0 | 4 |
| MRPL14 | EWSR1 | 0.743248 | 3 | 0 | 3 |
| MRPL14 | BYSL | 0.739403 | 8 | 0 | 7 |
| MRPL14 | TTLL4 | 0.737106 | 3 | 0 | 3 |
| MRPL14 | TMPO | 0.736342 | 4 | 0 | 4 |
| MRPL14 | MRPL27 | 0.733475 | 3 | 0 | 3 |
| MRPL14 | FANCE | 0.733464 | 7 | 0 | 7 |
| MRPL14 | EHMT2 | 0.732691 | 3 | 0 | 3 |
For details and further investigation, click here
