| Full name: magnesium transporter MRS2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 57380 | HGNC ID: HGNC:13785 | Ensembl Gene: ENSG00000124532 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MRS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRS2 | 57380 | 218538_s_at | 0.7171 | 0.0982 | |
| GSE20347 | MRS2 | 57380 | 218538_s_at | 0.4976 | 0.0381 | |
| GSE23400 | MRS2 | 57380 | 218536_at | -0.0148 | 0.8761 | |
| GSE26886 | MRS2 | 57380 | 218538_s_at | 0.1097 | 0.8050 | |
| GSE29001 | MRS2 | 57380 | 218536_at | 0.1099 | 0.6891 | |
| GSE38129 | MRS2 | 57380 | 218538_s_at | 0.6195 | 0.0001 | |
| GSE45670 | MRS2 | 57380 | 218538_s_at | 0.2417 | 0.1807 | |
| GSE53622 | MRS2 | 57380 | 113313 | 0.1375 | 0.0503 | |
| GSE53624 | MRS2 | 57380 | 113313 | 0.2294 | 0.0039 | |
| GSE63941 | MRS2 | 57380 | 218538_s_at | 0.9708 | 0.0177 | |
| GSE77861 | MRS2 | 57380 | 218536_at | -0.0839 | 0.8377 | |
| GSE97050 | MRS2 | 57380 | A_33_P3372281 | 0.2015 | 0.3773 | |
| SRP007169 | MRS2 | 57380 | RNAseq | -0.0973 | 0.8083 | |
| SRP008496 | MRS2 | 57380 | RNAseq | 0.0179 | 0.9432 | |
| SRP064894 | MRS2 | 57380 | RNAseq | 0.0553 | 0.7608 | |
| SRP133303 | MRS2 | 57380 | RNAseq | 0.1994 | 0.1090 | |
| SRP159526 | MRS2 | 57380 | RNAseq | -0.0062 | 0.9812 | |
| SRP193095 | MRS2 | 57380 | RNAseq | -0.2641 | 0.0109 | |
| SRP219564 | MRS2 | 57380 | RNAseq | -0.1357 | 0.7218 | |
| TCGA | MRS2 | 57380 | RNAseq | -0.1487 | 0.0064 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRS2 | 57380 | 4 | 2 | 24 | |
| GSE20123 | MRS2 | 57380 | 4 | 2 | 24 | |
| GSE43470 | MRS2 | 57380 | 6 | 0 | 37 | |
| GSE46452 | MRS2 | 57380 | 1 | 9 | 49 | |
| GSE47630 | MRS2 | 57380 | 8 | 5 | 27 | |
| GSE54993 | MRS2 | 57380 | 1 | 1 | 68 | |
| GSE54994 | MRS2 | 57380 | 10 | 4 | 39 | |
| GSE60625 | MRS2 | 57380 | 0 | 1 | 10 | |
| GSE74703 | MRS2 | 57380 | 6 | 0 | 30 | |
| GSE74704 | MRS2 | 57380 | 1 | 1 | 18 | |
| TCGA | MRS2 | 57380 | 17 | 20 | 59 |
Total number of gains: 58; Total number of losses: 45; Total Number of normals: 385.
Somatic mutations of MRS2:
Generating mutation plots.
Highly correlated genes for MRS2:
Showing top 20/286 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRS2 | DHX33 | 0.699178 | 3 | 0 | 3 |
| MRS2 | TFB2M | 0.682054 | 7 | 0 | 7 |
| MRS2 | GPR180 | 0.670165 | 4 | 0 | 4 |
| MRS2 | WDR83 | 0.66924 | 3 | 0 | 3 |
| MRS2 | ZNF678 | 0.650625 | 3 | 0 | 3 |
| MRS2 | AURKB | 0.647956 | 5 | 0 | 4 |
| MRS2 | NUP62CL | 0.645156 | 5 | 0 | 5 |
| MRS2 | DHRS7B | 0.643558 | 3 | 0 | 3 |
| MRS2 | HMGB3 | 0.640464 | 4 | 0 | 3 |
| MRS2 | KIF14 | 0.637547 | 5 | 0 | 4 |
| MRS2 | RAN | 0.630298 | 7 | 0 | 7 |
| MRS2 | RMI1 | 0.630046 | 5 | 0 | 4 |
| MRS2 | SLC25A17 | 0.629969 | 4 | 0 | 3 |
| MRS2 | SNRPD1 | 0.626094 | 6 | 0 | 5 |
| MRS2 | RFC3 | 0.616954 | 6 | 0 | 4 |
| MRS2 | C16orf91 | 0.61678 | 4 | 0 | 4 |
| MRS2 | ZGRF1 | 0.616231 | 3 | 0 | 3 |
| MRS2 | BYSL | 0.614816 | 7 | 0 | 4 |
| MRS2 | ZNF670 | 0.61407 | 3 | 0 | 3 |
| MRS2 | TMEM68 | 0.605819 | 4 | 0 | 3 |
For details and further investigation, click here
