| Full name: zinc finger GRF-type containing 1 | Alias Symbol: FLJ11331 | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 55345 | HGNC ID: HGNC:25654 | Ensembl Gene: ENSG00000138658 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZGRF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZGRF1 | 55345 | 1565935_at | 0.5498 | 0.0250 | |
| GSE26886 | ZGRF1 | 55345 | 1565935_at | 0.0260 | 0.8256 | |
| GSE45670 | ZGRF1 | 55345 | 228859_at | 0.8657 | 0.0002 | |
| GSE53622 | ZGRF1 | 55345 | 133425 | 1.5639 | 0.0000 | |
| GSE53624 | ZGRF1 | 55345 | 124755 | 1.2755 | 0.0000 | |
| GSE63941 | ZGRF1 | 55345 | 1565935_at | 1.1688 | 0.0001 | |
| GSE77861 | ZGRF1 | 55345 | 1565935_at | 0.0921 | 0.4071 | |
| SRP007169 | ZGRF1 | 55345 | RNAseq | 1.5076 | 0.0031 | |
| SRP008496 | ZGRF1 | 55345 | RNAseq | 1.2349 | 0.0006 | |
| SRP064894 | ZGRF1 | 55345 | RNAseq | 0.3313 | 0.2359 | |
| SRP133303 | ZGRF1 | 55345 | RNAseq | 1.1784 | 0.0000 | |
| SRP159526 | ZGRF1 | 55345 | RNAseq | 1.1530 | 0.0176 | |
| SRP193095 | ZGRF1 | 55345 | RNAseq | 0.6836 | 0.0000 | |
| SRP219564 | ZGRF1 | 55345 | RNAseq | 0.6237 | 0.1191 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by ZGRF1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ZGRF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZGRF1 | 55345 | 1 | 13 | 16 | |
| GSE20123 | ZGRF1 | 55345 | 1 | 13 | 16 | |
| GSE43470 | ZGRF1 | 55345 | 0 | 14 | 29 | |
| GSE46452 | ZGRF1 | 55345 | 1 | 36 | 22 | |
| GSE47630 | ZGRF1 | 55345 | 0 | 20 | 20 | |
| GSE54993 | ZGRF1 | 55345 | 9 | 0 | 61 | |
| GSE54994 | ZGRF1 | 55345 | 1 | 11 | 41 | |
| GSE60625 | ZGRF1 | 55345 | 0 | 3 | 8 | |
| GSE74703 | ZGRF1 | 55345 | 0 | 12 | 24 | |
| GSE74704 | ZGRF1 | 55345 | 0 | 7 | 13 |
Total number of gains: 13; Total number of losses: 129; Total Number of normals: 250.
Somatic mutations of ZGRF1:
Generating mutation plots.
Highly correlated genes for ZGRF1:
Showing top 20/798 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZGRF1 | TOP2A | 0.773595 | 5 | 0 | 5 |
| ZGRF1 | NUF2 | 0.772979 | 5 | 0 | 5 |
| ZGRF1 | EXO1 | 0.768853 | 5 | 0 | 5 |
| ZGRF1 | PKMYT1 | 0.758558 | 3 | 0 | 3 |
| ZGRF1 | IPO9 | 0.757828 | 3 | 0 | 3 |
| ZGRF1 | TPX2 | 0.755633 | 5 | 0 | 5 |
| ZGRF1 | TACC3 | 0.751991 | 5 | 0 | 5 |
| ZGRF1 | MYBL2 | 0.751086 | 5 | 0 | 5 |
| ZGRF1 | TONSL | 0.750863 | 4 | 0 | 4 |
| ZGRF1 | AURKB | 0.748954 | 5 | 0 | 5 |
| ZGRF1 | CKS1B | 0.747082 | 5 | 0 | 5 |
| ZGRF1 | KIF4A | 0.746979 | 5 | 0 | 5 |
| ZGRF1 | MCM5 | 0.7448 | 4 | 0 | 4 |
| ZGRF1 | HELLS | 0.743338 | 5 | 0 | 5 |
| ZGRF1 | CENPF | 0.742038 | 5 | 0 | 5 |
| ZGRF1 | KNTC1 | 0.738837 | 6 | 0 | 5 |
| ZGRF1 | ATAD2 | 0.737167 | 5 | 0 | 5 |
| ZGRF1 | ASPM | 0.73604 | 5 | 0 | 5 |
| ZGRF1 | TRIP13 | 0.734458 | 5 | 0 | 5 |
| ZGRF1 | R3HDM1 | 0.732793 | 4 | 0 | 4 |
For details and further investigation, click here
