KIF14

 

Full name: kinesin family member 14 Alias Symbol: KIAA0042
Type: protein-coding gene Cytoband: 1q32.1
Entrez ID: 9928 HGNC ID: HGNC:19181 Ensembl Gene: ENSG00000118193 OMIM ID: 611279
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of KIF14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIF14 9928 206364_at 2.3524 0.0090
GSE20347 KIF14 9928 206364_at 2.0985 0.0000
GSE23400 KIF14 9928 206364_at 1.4734 0.0000
GSE26886 KIF14 9928 236641_at 1.0912 0.0070
GSE29001 KIF14 9928 206364_at 1.6477 0.0000
GSE38129 KIF14 9928 206364_at 2.2493 0.0000
GSE45670 KIF14 9928 206364_at 1.8996 0.0000
GSE53622 KIF14 9928 98985 2.4811 0.0000
GSE53624 KIF14 9928 98985 2.6361 0.0000
GSE63941 KIF14 9928 206364_at 2.8867 0.0004
GSE77861 KIF14 9928 206364_at 1.4768 0.0018
GSE97050 KIF14 9928 A_33_P3230548 1.8353 0.0970
SRP007169 KIF14 9928 RNAseq 2.8702 0.0000
SRP008496 KIF14 9928 RNAseq 2.3437 0.0000
SRP064894 KIF14 9928 RNAseq 1.9828 0.0000
SRP133303 KIF14 9928 RNAseq 2.1304 0.0000
SRP159526 KIF14 9928 RNAseq 2.1416 0.0000
SRP193095 KIF14 9928 RNAseq 1.5286 0.0000
SRP219564 KIF14 9928 RNAseq 1.8891 0.0117
TCGA KIF14 9928 RNAseq 1.5269 0.0000

Upregulated datasets: 19; Downregulated datasets: 0.  

 

Survival by KIF14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIF14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIF14 9928 11 0 19
GSE20123 KIF14 9928 11 0 19
GSE43470 KIF14 9928 6 0 37
GSE46452 KIF14 9928 3 1 55
GSE47630 KIF14 9928 14 0 26
GSE54993 KIF14 9928 0 6 64
GSE54994 KIF14 9928 15 0 38
GSE60625 KIF14 9928 0 0 11
GSE74703 KIF14 9928 6 0 30
GSE74704 KIF14 9928 5 0 15
TCGA KIF14 9928 43 4 49

Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.  

 

Somatic mutations of KIF14:

 

Generating mutation plots.

 

Highly correlated genes for KIF14:

 

Showing top 20/2123 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIF14ASPM0.88065513013
KIF14NEK20.87741913013
KIF14CENPF0.86683613012
KIF14KIF4A0.86670312012
KIF14CEP550.86484113012
KIF14NUF20.857814909
KIF14TOP2A0.85688613013
KIF14TPX20.85569913013
KIF14BUB1B0.85103910010
KIF14UBE2T0.848416909
KIF14DTL0.8475413012
KIF14CDK10.84541912012
KIF14NCAPH0.842841909
KIF14TRIP130.83549413013
KIF14KPNA20.83527710010
KIF14KIF230.8352113013
KIF14AURKB0.8350813013
KIF14TTK0.83419713012
KIF14MTFR20.832651707
KIF14PRC10.83237913013

For details and further investigation, click here