| Full name: transmembrane protein 68 | Alias Symbol: FLJ32370 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 137695 | HGNC ID: HGNC:26510 | Ensembl Gene: ENSG00000167904 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM68:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM68 | 137695 | 227936_at | 0.3880 | 0.5833 | |
| GSE26886 | TMEM68 | 137695 | 227936_at | 1.2532 | 0.0001 | |
| GSE45670 | TMEM68 | 137695 | 226483_at | 0.4989 | 0.0002 | |
| GSE53622 | TMEM68 | 137695 | 70345 | 0.5062 | 0.0000 | |
| GSE53624 | TMEM68 | 137695 | 70345 | 0.5357 | 0.0000 | |
| GSE63941 | TMEM68 | 137695 | 227936_at | 1.2508 | 0.0219 | |
| GSE77861 | TMEM68 | 137695 | 227936_at | 0.3626 | 0.2799 | |
| GSE97050 | TMEM68 | 137695 | A_23_P136172 | 0.2830 | 0.2268 | |
| SRP007169 | TMEM68 | 137695 | RNAseq | 0.4713 | 0.2370 | |
| SRP008496 | TMEM68 | 137695 | RNAseq | 0.7718 | 0.0100 | |
| SRP064894 | TMEM68 | 137695 | RNAseq | 0.5555 | 0.0216 | |
| SRP133303 | TMEM68 | 137695 | RNAseq | 0.3165 | 0.0760 | |
| SRP159526 | TMEM68 | 137695 | RNAseq | 0.3413 | 0.1978 | |
| SRP193095 | TMEM68 | 137695 | RNAseq | -0.0051 | 0.9667 | |
| SRP219564 | TMEM68 | 137695 | RNAseq | 0.2181 | 0.5500 | |
| TCGA | TMEM68 | 137695 | RNAseq | 0.1745 | 0.0040 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TMEM68 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM68:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM68 | 137695 | 14 | 1 | 15 | |
| GSE20123 | TMEM68 | 137695 | 14 | 1 | 15 | |
| GSE43470 | TMEM68 | 137695 | 13 | 3 | 27 | |
| GSE46452 | TMEM68 | 137695 | 20 | 3 | 36 | |
| GSE47630 | TMEM68 | 137695 | 23 | 1 | 16 | |
| GSE54993 | TMEM68 | 137695 | 1 | 16 | 53 | |
| GSE54994 | TMEM68 | 137695 | 28 | 0 | 25 | |
| GSE60625 | TMEM68 | 137695 | 0 | 4 | 7 | |
| GSE74703 | TMEM68 | 137695 | 12 | 2 | 22 | |
| GSE74704 | TMEM68 | 137695 | 10 | 0 | 10 | |
| TCGA | TMEM68 | 137695 | 43 | 8 | 45 |
Total number of gains: 178; Total number of losses: 39; Total Number of normals: 271.
Somatic mutations of TMEM68:
Generating mutation plots.
Highly correlated genes for TMEM68:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM68 | EYS | 0.707945 | 3 | 0 | 3 |
| TMEM68 | NPW | 0.69248 | 3 | 0 | 3 |
| TMEM68 | DPM3 | 0.671803 | 3 | 0 | 3 |
| TMEM68 | IL12RB2 | 0.66867 | 4 | 0 | 3 |
| TMEM68 | RPL30 | 0.661766 | 3 | 0 | 3 |
| TMEM68 | RAD54B | 0.661561 | 5 | 0 | 5 |
| TMEM68 | FOXL2 | 0.652869 | 3 | 0 | 3 |
| TMEM68 | LAS1L | 0.649851 | 4 | 0 | 3 |
| TMEM68 | PRPF19 | 0.649525 | 4 | 0 | 3 |
| TMEM68 | IL15RA | 0.647733 | 3 | 0 | 3 |
| TMEM68 | MAPK8IP2 | 0.64772 | 3 | 0 | 3 |
| TMEM68 | CEP19 | 0.645522 | 4 | 0 | 3 |
| TMEM68 | ATP8B3 | 0.642528 | 3 | 0 | 3 |
| TMEM68 | TRIM11 | 0.637801 | 3 | 0 | 3 |
| TMEM68 | FAM24B | 0.635982 | 3 | 0 | 3 |
| TMEM68 | DNLZ | 0.630982 | 4 | 0 | 3 |
| TMEM68 | ZWINT | 0.630849 | 5 | 0 | 4 |
| TMEM68 | SLC4A11 | 0.630709 | 4 | 0 | 3 |
| TMEM68 | SMG7 | 0.630449 | 3 | 0 | 3 |
| TMEM68 | ZNF77 | 0.630253 | 4 | 0 | 3 |
For details and further investigation, click here
