| Full name: high mobility group box 3 | Alias Symbol: HMG2A|MGC90319 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 3149 | HGNC ID: HGNC:5004 | Ensembl Gene: ENSG00000029993 | OMIM ID: 300193 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HMGB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMGB3 | 3149 | 203744_at | 1.5721 | 0.0090 | |
| GSE20347 | HMGB3 | 3149 | 203744_at | 1.6099 | 0.0000 | |
| GSE23400 | HMGB3 | 3149 | 203744_at | 1.7451 | 0.0000 | |
| GSE26886 | HMGB3 | 3149 | 203744_at | 1.0000 | 0.0000 | |
| GSE29001 | HMGB3 | 3149 | 203744_at | 1.4822 | 0.0001 | |
| GSE38129 | HMGB3 | 3149 | 203744_at | 1.7737 | 0.0000 | |
| GSE45670 | HMGB3 | 3149 | 203744_at | 1.7888 | 0.0000 | |
| GSE53622 | HMGB3 | 3149 | 46370 | 1.1639 | 0.0000 | |
| GSE53624 | HMGB3 | 3149 | 46370 | 1.2753 | 0.0000 | |
| GSE63941 | HMGB3 | 3149 | 203744_at | 1.5703 | 0.0171 | |
| GSE77861 | HMGB3 | 3149 | 203744_at | 1.5017 | 0.0018 | |
| GSE97050 | HMGB3 | 3149 | A_33_P3237359 | 0.4210 | 0.1836 | |
| SRP007169 | HMGB3 | 3149 | RNAseq | 2.3748 | 0.0000 | |
| SRP008496 | HMGB3 | 3149 | RNAseq | 2.3871 | 0.0000 | |
| SRP064894 | HMGB3 | 3149 | RNAseq | 1.9152 | 0.0000 | |
| SRP133303 | HMGB3 | 3149 | RNAseq | 1.9663 | 0.0000 | |
| SRP159526 | HMGB3 | 3149 | RNAseq | 2.5371 | 0.0000 | |
| SRP193095 | HMGB3 | 3149 | RNAseq | 1.3095 | 0.0000 | |
| TCGA | HMGB3 | 3149 | RNAseq | 0.8058 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by HMGB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMGB3:
No record found for this gene.
Somatic mutations of HMGB3:
Generating mutation plots.
Highly correlated genes for HMGB3:
Showing top 20/2062 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMGB3 | CENPF | 0.808939 | 11 | 0 | 11 |
| HMGB3 | WDR4 | 0.807864 | 3 | 0 | 3 |
| HMGB3 | UBE2C | 0.800033 | 12 | 0 | 12 |
| HMGB3 | CMSS1 | 0.789444 | 6 | 0 | 6 |
| HMGB3 | TIMELESS | 0.785132 | 12 | 0 | 12 |
| HMGB3 | SIX4 | 0.784536 | 7 | 0 | 7 |
| HMGB3 | TPX2 | 0.784087 | 12 | 0 | 12 |
| HMGB3 | MCM2 | 0.776027 | 11 | 0 | 11 |
| HMGB3 | MYBL2 | 0.776025 | 12 | 0 | 12 |
| HMGB3 | CDCA2 | 0.768487 | 6 | 0 | 5 |
| HMGB3 | DNMT1 | 0.767506 | 12 | 0 | 11 |
| HMGB3 | NCAPH | 0.763995 | 10 | 0 | 9 |
| HMGB3 | C1orf112 | 0.76177 | 10 | 0 | 10 |
| HMGB3 | PNPT1 | 0.761581 | 5 | 0 | 5 |
| HMGB3 | ACLY | 0.76088 | 11 | 0 | 11 |
| HMGB3 | CKS1B | 0.760183 | 12 | 0 | 12 |
| HMGB3 | GNPNAT1 | 0.759192 | 3 | 0 | 3 |
| HMGB3 | ECT2 | 0.757263 | 11 | 0 | 10 |
| HMGB3 | MARCKSL1 | 0.756534 | 11 | 0 | 11 |
| HMGB3 | CD276 | 0.755551 | 4 | 0 | 4 |
For details and further investigation, click here
