| Full name: zinc finger protein 678 | Alias Symbol: MGC42493 | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 339500 | HGNC ID: HGNC:28652 | Ensembl Gene: ENSG00000181450 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF678:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF678 | 339500 | 242923_at | 0.9773 | 0.0843 | |
| GSE26886 | ZNF678 | 339500 | 242923_at | 0.7234 | 0.0429 | |
| GSE45670 | ZNF678 | 339500 | 242923_at | 0.4137 | 0.0956 | |
| GSE53622 | ZNF678 | 339500 | 83395 | 0.3564 | 0.0001 | |
| GSE53624 | ZNF678 | 339500 | 83395 | 0.3507 | 0.0000 | |
| GSE63941 | ZNF678 | 339500 | 242923_at | -0.7273 | 0.1563 | |
| GSE77861 | ZNF678 | 339500 | 232028_at | 0.4509 | 0.2752 | |
| GSE97050 | ZNF678 | A_19_P00317449 | 0.2417 | 0.3349 | ||
| SRP007169 | ZNF678 | 339500 | RNAseq | 0.5659 | 0.2033 | |
| SRP008496 | ZNF678 | 339500 | RNAseq | 0.8084 | 0.0189 | |
| SRP064894 | ZNF678 | 339500 | RNAseq | 0.6732 | 0.0002 | |
| SRP133303 | ZNF678 | 339500 | RNAseq | 0.1999 | 0.1320 | |
| SRP159526 | ZNF678 | 339500 | RNAseq | 0.1220 | 0.7173 | |
| SRP193095 | ZNF678 | 339500 | RNAseq | 0.1148 | 0.2123 | |
| SRP219564 | ZNF678 | 339500 | RNAseq | 0.8318 | 0.0003 | |
| TCGA | ZNF678 | 339500 | RNAseq | -0.0330 | 0.7897 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF678 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF678:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF678 | 339500 | 11 | 0 | 19 | |
| GSE20123 | ZNF678 | 339500 | 11 | 0 | 19 | |
| GSE43470 | ZNF678 | 339500 | 7 | 1 | 35 | |
| GSE46452 | ZNF678 | 339500 | 3 | 1 | 55 | |
| GSE47630 | ZNF678 | 339500 | 15 | 0 | 25 | |
| GSE54993 | ZNF678 | 339500 | 0 | 6 | 64 | |
| GSE54994 | ZNF678 | 339500 | 17 | 0 | 36 | |
| GSE60625 | ZNF678 | 339500 | 0 | 0 | 11 | |
| GSE74703 | ZNF678 | 339500 | 7 | 1 | 28 | |
| GSE74704 | ZNF678 | 339500 | 5 | 0 | 15 | |
| TCGA | ZNF678 | 339500 | 45 | 2 | 49 |
Total number of gains: 121; Total number of losses: 11; Total Number of normals: 356.
Somatic mutations of ZNF678:
Generating mutation plots.
Highly correlated genes for ZNF678:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF678 | CHP2 | 0.767764 | 3 | 0 | 3 |
| ZNF678 | PPM1F | 0.754933 | 3 | 0 | 3 |
| ZNF678 | TAF5L | 0.754554 | 5 | 0 | 5 |
| ZNF678 | SMARCB1 | 0.746436 | 3 | 0 | 3 |
| ZNF678 | RBM25 | 0.723992 | 3 | 0 | 3 |
| ZNF678 | TAF5 | 0.717092 | 3 | 0 | 3 |
| ZNF678 | ZNF639 | 0.69731 | 4 | 0 | 3 |
| ZNF678 | PLEKHA1 | 0.685874 | 3 | 0 | 3 |
| ZNF678 | AMPD2 | 0.673593 | 4 | 0 | 3 |
| ZNF678 | DCAF12L2 | 0.670442 | 3 | 0 | 3 |
| ZNF678 | IPO9 | 0.666977 | 4 | 0 | 4 |
| ZNF678 | TARBP2 | 0.664061 | 3 | 0 | 3 |
| ZNF678 | HAUS8 | 0.657775 | 4 | 0 | 3 |
| ZNF678 | TRAM1L1 | 0.652953 | 3 | 0 | 3 |
| ZNF678 | MRS2 | 0.650625 | 3 | 0 | 3 |
| ZNF678 | TAF4 | 0.650274 | 4 | 0 | 3 |
| ZNF678 | KLC2 | 0.648144 | 3 | 0 | 3 |
| ZNF678 | ODC1 | 0.646679 | 4 | 0 | 3 |
| ZNF678 | HOXC9 | 0.646356 | 5 | 0 | 3 |
| ZNF678 | SDCCAG8 | 0.64427 | 4 | 0 | 3 |
For details and further investigation, click here
