| Full name: MSL complex subunit 2 | Alias Symbol: FLJ10546|KIAA1585|msl-2 | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 55167 | HGNC ID: HGNC:25544 | Ensembl Gene: ENSG00000174579 | OMIM ID: 614802 |
| Drug and gene relationship at DGIdb | |||
Expression of MSL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MSL2 | 55167 | 218733_at | 0.8659 | 0.1183 | |
| GSE20347 | MSL2 | 55167 | 218733_at | 0.8360 | 0.0000 | |
| GSE23400 | MSL2 | 55167 | 218733_at | 0.7051 | 0.0000 | |
| GSE26886 | MSL2 | 55167 | 218733_at | -1.1634 | 0.0012 | |
| GSE29001 | MSL2 | 55167 | 218733_at | 0.7962 | 0.0479 | |
| GSE38129 | MSL2 | 55167 | 218733_at | 0.7024 | 0.0082 | |
| GSE45670 | MSL2 | 55167 | 218733_at | 0.4607 | 0.0128 | |
| GSE53622 | MSL2 | 55167 | 112195 | 0.2441 | 0.0031 | |
| GSE53624 | MSL2 | 55167 | 112195 | 0.3836 | 0.0000 | |
| GSE63941 | MSL2 | 55167 | 218733_at | -0.0324 | 0.9585 | |
| GSE77861 | MSL2 | 55167 | 218733_at | 0.6045 | 0.0959 | |
| GSE97050 | MSL2 | 55167 | A_23_P132438 | 0.1970 | 0.4689 | |
| SRP007169 | MSL2 | 55167 | RNAseq | 0.7909 | 0.0213 | |
| SRP008496 | MSL2 | 55167 | RNAseq | 0.9217 | 0.0000 | |
| SRP064894 | MSL2 | 55167 | RNAseq | 0.4270 | 0.0077 | |
| SRP133303 | MSL2 | 55167 | RNAseq | 0.4265 | 0.0067 | |
| SRP159526 | MSL2 | 55167 | RNAseq | 0.7498 | 0.0010 | |
| SRP193095 | MSL2 | 55167 | RNAseq | 0.2790 | 0.0007 | |
| SRP219564 | MSL2 | 55167 | RNAseq | 0.4191 | 0.1089 | |
| TCGA | MSL2 | 55167 | RNAseq | 0.1054 | 0.0655 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MSL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MSL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MSL2 | 55167 | 16 | 0 | 14 | |
| GSE20123 | MSL2 | 55167 | 16 | 0 | 14 | |
| GSE43470 | MSL2 | 55167 | 22 | 0 | 21 | |
| GSE46452 | MSL2 | 55167 | 15 | 4 | 40 | |
| GSE47630 | MSL2 | 55167 | 18 | 3 | 19 | |
| GSE54993 | MSL2 | 55167 | 2 | 8 | 60 | |
| GSE54994 | MSL2 | 55167 | 32 | 1 | 20 | |
| GSE60625 | MSL2 | 55167 | 0 | 6 | 5 | |
| GSE74703 | MSL2 | 55167 | 19 | 0 | 17 | |
| GSE74704 | MSL2 | 55167 | 11 | 0 | 9 | |
| TCGA | MSL2 | 55167 | 60 | 5 | 31 |
Total number of gains: 211; Total number of losses: 27; Total Number of normals: 250.
Somatic mutations of MSL2:
Generating mutation plots.
Highly correlated genes for MSL2:
Showing top 20/897 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MSL2 | TATDN2 | 0.802937 | 3 | 0 | 3 |
| MSL2 | NR2C2 | 0.796622 | 3 | 0 | 3 |
| MSL2 | ZNF484 | 0.774127 | 3 | 0 | 3 |
| MSL2 | SBNO1 | 0.770818 | 3 | 0 | 3 |
| MSL2 | LRRC58 | 0.766009 | 5 | 0 | 4 |
| MSL2 | ZNF607 | 0.758061 | 3 | 0 | 3 |
| MSL2 | RALGAPB | 0.757288 | 3 | 0 | 3 |
| MSL2 | GNA11 | 0.74721 | 3 | 0 | 3 |
| MSL2 | USP36 | 0.745001 | 4 | 0 | 4 |
| MSL2 | ZNF766 | 0.743182 | 3 | 0 | 3 |
| MSL2 | ASB8 | 0.734145 | 3 | 0 | 3 |
| MSL2 | SGSH | 0.73379 | 3 | 0 | 3 |
| MSL2 | TNFRSF1B | 0.733449 | 3 | 0 | 3 |
| MSL2 | AP3D1 | 0.732171 | 3 | 0 | 3 |
| MSL2 | NEURL1B | 0.726421 | 3 | 0 | 3 |
| MSL2 | GPR107 | 0.722944 | 4 | 0 | 3 |
| MSL2 | SMAD1 | 0.721408 | 4 | 0 | 4 |
| MSL2 | DEXI | 0.721197 | 3 | 0 | 3 |
| MSL2 | SENP1 | 0.720753 | 3 | 0 | 3 |
| MSL2 | DNAJC7 | 0.718122 | 4 | 0 | 3 |
For details and further investigation, click here
