| Full name: ubiquitin specific peptidase 36 | Alias Symbol: KIAA1453|FLJ12851 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 57602 | HGNC ID: HGNC:20062 | Ensembl Gene: | OMIM ID: 612543 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of USP36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP36 | 57602 | 224978_s_at | 0.6841 | 0.0471 | |
| GSE20347 | USP36 | 57602 | 220370_s_at | 0.2250 | 0.0670 | |
| GSE23400 | USP36 | 57602 | 220370_s_at | 0.1078 | 0.0405 | |
| GSE26886 | USP36 | 57602 | 227093_at | -0.0466 | 0.8470 | |
| GSE29001 | USP36 | 57602 | 220370_s_at | 0.2858 | 0.5552 | |
| GSE38129 | USP36 | 57602 | 220370_s_at | 0.2237 | 0.1948 | |
| GSE45670 | USP36 | 57602 | 224979_s_at | 0.1330 | 0.2235 | |
| GSE53622 | USP36 | 57602 | 3894 | 0.3066 | 0.0004 | |
| GSE53624 | USP36 | 57602 | 3894 | 0.5767 | 0.0000 | |
| GSE63941 | USP36 | 57602 | 224978_s_at | 0.2738 | 0.5501 | |
| GSE77861 | USP36 | 57602 | 224979_s_at | -0.0708 | 0.5639 | |
| GSE97050 | USP36 | 57602 | A_33_P3357247 | 0.2997 | 0.1971 | |
| SRP007169 | USP36 | 57602 | RNAseq | 1.9321 | 0.0000 | |
| SRP008496 | USP36 | 57602 | RNAseq | 1.7197 | 0.0000 | |
| SRP064894 | USP36 | 57602 | RNAseq | 0.2986 | 0.1398 | |
| SRP133303 | USP36 | 57602 | RNAseq | 0.2712 | 0.1370 | |
| SRP159526 | USP36 | 57602 | RNAseq | 0.3018 | 0.2679 | |
| SRP193095 | USP36 | 57602 | RNAseq | 0.6645 | 0.0001 | |
| SRP219564 | USP36 | 57602 | RNAseq | 0.1157 | 0.5754 | |
| TCGA | USP36 | 57602 | RNAseq | -0.0582 | 0.2103 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by USP36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP36 | 57602 | 4 | 3 | 23 | |
| GSE20123 | USP36 | 57602 | 4 | 3 | 23 | |
| GSE43470 | USP36 | 57602 | 3 | 4 | 36 | |
| GSE46452 | USP36 | 57602 | 33 | 0 | 26 | |
| GSE47630 | USP36 | 57602 | 8 | 1 | 31 | |
| GSE54993 | USP36 | 57602 | 2 | 5 | 63 | |
| GSE54994 | USP36 | 57602 | 10 | 5 | 38 | |
| GSE60625 | USP36 | 57602 | 6 | 0 | 5 | |
| GSE74703 | USP36 | 57602 | 3 | 2 | 31 | |
| GSE74704 | USP36 | 57602 | 4 | 3 | 13 | |
| TCGA | USP36 | 57602 | 30 | 9 | 57 |
Total number of gains: 107; Total number of losses: 35; Total Number of normals: 346.
Somatic mutations of USP36:
Generating mutation plots.
Highly correlated genes for USP36:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP36 | FOXP4 | 0.826185 | 3 | 0 | 3 |
| USP36 | UBAP2L | 0.803398 | 3 | 0 | 3 |
| USP36 | IGF2R | 0.796735 | 3 | 0 | 3 |
| USP36 | ZNF584 | 0.783012 | 3 | 0 | 3 |
| USP36 | ARFRP1 | 0.774701 | 3 | 0 | 3 |
| USP36 | PDRG1 | 0.773071 | 3 | 0 | 3 |
| USP36 | ZNF644 | 0.770556 | 3 | 0 | 3 |
| USP36 | MCOLN1 | 0.767047 | 3 | 0 | 3 |
| USP36 | PPP1R37 | 0.766317 | 3 | 0 | 3 |
| USP36 | SLC25A19 | 0.766077 | 3 | 0 | 3 |
| USP36 | PCCB | 0.750809 | 3 | 0 | 3 |
| USP36 | TP53I11 | 0.750483 | 3 | 0 | 3 |
| USP36 | MSL2 | 0.745001 | 4 | 0 | 4 |
| USP36 | BLCAP | 0.739967 | 3 | 0 | 3 |
| USP36 | HGS | 0.73267 | 4 | 0 | 4 |
| USP36 | MED26 | 0.732469 | 3 | 0 | 3 |
| USP36 | RSRC1 | 0.732377 | 4 | 0 | 3 |
| USP36 | ROMO1 | 0.731893 | 3 | 0 | 3 |
| USP36 | ZNF683 | 0.725566 | 3 | 0 | 3 |
| USP36 | RNFT2 | 0.719619 | 3 | 0 | 3 |
For details and further investigation, click here
