| Full name: Ral GTPase activating protein non-catalytic beta subunit | Alias Symbol: DKFZp781M2411|RalGAPbeta | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 57148 | HGNC ID: HGNC:29221 | Ensembl Gene: ENSG00000170471 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RALGAPB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RALGAPB | 57148 | 221736_at | 0.4982 | 0.1621 | |
| GSE20347 | RALGAPB | 57148 | 221736_at | -0.2748 | 0.0338 | |
| GSE23400 | RALGAPB | 57148 | 221736_at | 0.0044 | 0.9416 | |
| GSE26886 | RALGAPB | 57148 | 221736_at | -0.7378 | 0.0136 | |
| GSE29001 | RALGAPB | 57148 | 221736_at | 0.2513 | 0.1570 | |
| GSE38129 | RALGAPB | 57148 | 221736_at | -0.1238 | 0.2938 | |
| GSE45670 | RALGAPB | 57148 | 221736_at | -0.0092 | 0.9552 | |
| GSE53622 | RALGAPB | 57148 | 93741 | 0.2877 | 0.0000 | |
| GSE53624 | RALGAPB | 57148 | 93741 | 0.0643 | 0.5510 | |
| GSE63941 | RALGAPB | 57148 | 221736_at | -0.8294 | 0.0088 | |
| GSE77861 | RALGAPB | 57148 | 221736_at | -0.0816 | 0.6521 | |
| GSE97050 | RALGAPB | 57148 | A_33_P3245709 | 0.4362 | 0.1858 | |
| SRP007169 | RALGAPB | 57148 | RNAseq | -0.0793 | 0.8100 | |
| SRP008496 | RALGAPB | 57148 | RNAseq | -0.0596 | 0.7319 | |
| SRP064894 | RALGAPB | 57148 | RNAseq | -0.1291 | 0.5041 | |
| SRP133303 | RALGAPB | 57148 | RNAseq | 0.1900 | 0.0641 | |
| SRP159526 | RALGAPB | 57148 | RNAseq | -0.2720 | 0.1594 | |
| SRP193095 | RALGAPB | 57148 | RNAseq | -0.1215 | 0.1143 | |
| SRP219564 | RALGAPB | 57148 | RNAseq | -0.0072 | 0.9822 | |
| TCGA | RALGAPB | 57148 | RNAseq | -0.0417 | 0.3354 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RALGAPB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RALGAPB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RALGAPB | 57148 | 14 | 2 | 14 | |
| GSE20123 | RALGAPB | 57148 | 14 | 2 | 14 | |
| GSE43470 | RALGAPB | 57148 | 13 | 0 | 30 | |
| GSE46452 | RALGAPB | 57148 | 29 | 0 | 30 | |
| GSE47630 | RALGAPB | 57148 | 24 | 0 | 16 | |
| GSE54993 | RALGAPB | 57148 | 0 | 17 | 53 | |
| GSE54994 | RALGAPB | 57148 | 24 | 0 | 29 | |
| GSE60625 | RALGAPB | 57148 | 0 | 0 | 11 | |
| GSE74703 | RALGAPB | 57148 | 10 | 0 | 26 | |
| GSE74704 | RALGAPB | 57148 | 10 | 1 | 9 | |
| TCGA | RALGAPB | 57148 | 47 | 4 | 45 |
Total number of gains: 185; Total number of losses: 26; Total Number of normals: 277.
Somatic mutations of RALGAPB:
Generating mutation plots.
Highly correlated genes for RALGAPB:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RALGAPB | DPY19L3 | 0.826141 | 3 | 0 | 3 |
| RALGAPB | TRRAP | 0.786449 | 3 | 0 | 3 |
| RALGAPB | TP53RK | 0.786197 | 3 | 0 | 3 |
| RALGAPB | USP42 | 0.777237 | 3 | 0 | 3 |
| RALGAPB | ZDHHC16 | 0.772769 | 3 | 0 | 3 |
| RALGAPB | MSL2 | 0.757288 | 3 | 0 | 3 |
| RALGAPB | PIGU | 0.753378 | 5 | 0 | 5 |
| RALGAPB | SCOC | 0.753249 | 3 | 0 | 3 |
| RALGAPB | SENP1 | 0.743674 | 3 | 0 | 3 |
| RALGAPB | SNX18 | 0.742247 | 3 | 0 | 3 |
| RALGAPB | ZNF318 | 0.740701 | 3 | 0 | 3 |
| RALGAPB | MAK16 | 0.738454 | 3 | 0 | 3 |
| RALGAPB | AMZ2 | 0.737981 | 3 | 0 | 3 |
| RALGAPB | KBTBD6 | 0.734633 | 4 | 0 | 4 |
| RALGAPB | LSM1 | 0.728872 | 3 | 0 | 3 |
| RALGAPB | RCOR1 | 0.725876 | 3 | 0 | 3 |
| RALGAPB | YIF1A | 0.724398 | 3 | 0 | 3 |
| RALGAPB | SAR1A | 0.724226 | 3 | 0 | 3 |
| RALGAPB | MDM2 | 0.72335 | 3 | 0 | 3 |
| RALGAPB | STK38 | 0.722294 | 3 | 0 | 3 |
For details and further investigation, click here
