TNFRSF1B

 

Full name: TNF receptor superfamily member 1B Alias Symbol: TNFBR|TNFR80|TNF-R75|TNF-R-II|p75|CD120b
Type: protein-coding gene Cytoband: 1p36.22
Entrez ID: 7133 HGNC ID: HGNC:11917 Ensembl Gene: ENSG00000028137 OMIM ID: 191191
Drug and gene relationship at DGIdb

 

TNFRSF1B involved pathways:

KEGG pathway Description View
hsa04668TNF signaling pathway
hsa04920Adipocytokine signaling pathway
hsa05014Amyotrophic lateral sclerosis (ALS)

 

Expression of TNFRSF1B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TNFRSF1B 7133 203508_at 0.2588 0.7514
GSE20347 TNFRSF1B 7133 203508_at 0.1577 0.4588
GSE23400 TNFRSF1B 7133 203508_at 0.0774 0.1470
GSE26886 TNFRSF1B 7133 203508_at 0.2887 0.4649
GSE29001 TNFRSF1B 7133 203508_at 0.8353 0.0091
GSE38129 TNFRSF1B 7133 203508_at 0.0141 0.9661
GSE45670 TNFRSF1B 7133 203508_at -0.1719 0.5859
GSE53622 TNFRSF1B 7133 21519 0.2051 0.0672
GSE53624 TNFRSF1B 7133 2160 0.2481 0.0445
GSE63941 TNFRSF1B 7133 203508_at -1.7425 0.0038
GSE77861 TNFRSF1B 7133 203508_at 0.1788 0.3688
GSE97050 TNFRSF1B 7133 A_33_P3322274 0.6829 0.1518
SRP007169 TNFRSF1B 7133 RNAseq 1.1989 0.0727
SRP008496 TNFRSF1B 7133 RNAseq 0.7498 0.1090
SRP064894 TNFRSF1B 7133 RNAseq 0.6386 0.0528
SRP133303 TNFRSF1B 7133 RNAseq 0.3356 0.1059
SRP159526 TNFRSF1B 7133 RNAseq 0.0265 0.9605
SRP193095 TNFRSF1B 7133 RNAseq 0.8920 0.0005
SRP219564 TNFRSF1B 7133 RNAseq 0.7182 0.1306
TCGA TNFRSF1B 7133 RNAseq -0.2158 0.0467

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by TNFRSF1B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TNFRSF1B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TNFRSF1B 7133 0 5 25
GSE20123 TNFRSF1B 7133 0 4 26
GSE43470 TNFRSF1B 7133 4 6 33
GSE46452 TNFRSF1B 7133 7 1 51
GSE47630 TNFRSF1B 7133 8 4 28
GSE54993 TNFRSF1B 7133 3 1 66
GSE54994 TNFRSF1B 7133 11 4 38
GSE60625 TNFRSF1B 7133 0 0 11
GSE74703 TNFRSF1B 7133 3 4 29
GSE74704 TNFRSF1B 7133 0 0 20
TCGA TNFRSF1B 7133 10 22 64

Total number of gains: 46; Total number of losses: 51; Total Number of normals: 391.  

 

Somatic mutations of TNFRSF1B:

 

Generating mutation plots.

 

Highly correlated genes for TNFRSF1B:

 

Showing top 20/804 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TNFRSF1BC1orf1620.769844707
TNFRSF1BNCKAP1L0.7690410010
TNFRSF1BARHGAP90.755494707
TNFRSF1BA1BG0.74684303
TNFRSF1BOAZ10.744325303
TNFRSF1BSRGN0.74137712011
TNFRSF1BFMNL10.740079505
TNFRSF1BC19orf380.738209303
TNFRSF1BLAPTM50.73759512010
TNFRSF1BGMFG0.73717512012
TNFRSF1BPREX10.734994605
TNFRSF1BMSL20.733449303
TNFRSF1BHAVCR20.732833505
TNFRSF1BRASSF40.732181606
TNFRSF1BITGB20.72927512011
TNFRSF1BCD380.726388303
TNFRSF1BMYO1F0.72621811010
TNFRSF1BCD140.72580411010
TNFRSF1BSURF40.725645303
TNFRSF1BSMAP20.721219606

For details and further investigation, click here