| Full name: secretion associated Ras related GTPase 1B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 51128 | HGNC ID: HGNC:10535 | Ensembl Gene: ENSG00000152700 | OMIM ID: 607690 |
| Drug and gene relationship at DGIdb | |||
Expression of SAR1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAR1B | 51128 | 226742_at | -0.4216 | 0.3747 | |
| GSE20347 | SAR1B | 51128 | 218254_s_at | -1.1021 | 0.0000 | |
| GSE23400 | SAR1B | 51128 | 218254_s_at | -0.5548 | 0.0000 | |
| GSE26886 | SAR1B | 51128 | 218254_s_at | -1.0183 | 0.0000 | |
| GSE29001 | SAR1B | 51128 | 218254_s_at | -0.8747 | 0.0021 | |
| GSE38129 | SAR1B | 51128 | 218254_s_at | -0.6927 | 0.0009 | |
| GSE45670 | SAR1B | 51128 | 218254_s_at | -0.0698 | 0.8076 | |
| GSE53622 | SAR1B | 51128 | 3447 | -0.6032 | 0.0000 | |
| GSE53624 | SAR1B | 51128 | 3447 | -0.5617 | 0.0000 | |
| GSE63941 | SAR1B | 51128 | 218254_s_at | -0.3830 | 0.3973 | |
| GSE77861 | SAR1B | 51128 | 218254_s_at | -1.3583 | 0.0239 | |
| GSE97050 | SAR1B | 51128 | A_23_P92842 | 0.1109 | 0.7027 | |
| SRP007169 | SAR1B | 51128 | RNAseq | -1.4802 | 0.0000 | |
| SRP008496 | SAR1B | 51128 | RNAseq | -1.4177 | 0.0000 | |
| SRP064894 | SAR1B | 51128 | RNAseq | -0.6637 | 0.0000 | |
| SRP133303 | SAR1B | 51128 | RNAseq | -0.2286 | 0.1367 | |
| SRP159526 | SAR1B | 51128 | RNAseq | -0.6479 | 0.0734 | |
| SRP193095 | SAR1B | 51128 | RNAseq | -0.9526 | 0.0000 | |
| SRP219564 | SAR1B | 51128 | RNAseq | -0.4276 | 0.1560 | |
| TCGA | SAR1B | 51128 | RNAseq | -0.1980 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SAR1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAR1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAR1B | 51128 | 3 | 11 | 16 | |
| GSE20123 | SAR1B | 51128 | 4 | 11 | 15 | |
| GSE43470 | SAR1B | 51128 | 2 | 8 | 33 | |
| GSE46452 | SAR1B | 51128 | 0 | 27 | 32 | |
| GSE47630 | SAR1B | 51128 | 0 | 21 | 19 | |
| GSE54993 | SAR1B | 51128 | 9 | 1 | 60 | |
| GSE54994 | SAR1B | 51128 | 2 | 14 | 37 | |
| GSE60625 | SAR1B | 51128 | 0 | 0 | 11 | |
| GSE74703 | SAR1B | 51128 | 2 | 5 | 29 | |
| GSE74704 | SAR1B | 51128 | 3 | 5 | 12 | |
| TCGA | SAR1B | 51128 | 3 | 36 | 57 |
Total number of gains: 28; Total number of losses: 139; Total Number of normals: 321.
Somatic mutations of SAR1B:
Generating mutation plots.
Highly correlated genes for SAR1B:
Showing top 20/1378 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAR1B | WDFY1 | 0.775575 | 3 | 0 | 3 |
| SAR1B | PPP2CA | 0.728027 | 12 | 0 | 11 |
| SAR1B | CWH43 | 0.722079 | 10 | 0 | 10 |
| SAR1B | FAM174A | 0.719519 | 8 | 0 | 7 |
| SAR1B | RABGGTA | 0.717126 | 11 | 0 | 11 |
| SAR1B | ENDOU | 0.716936 | 10 | 0 | 10 |
| SAR1B | ARF6 | 0.716476 | 10 | 0 | 9 |
| SAR1B | ARRDC3 | 0.714666 | 7 | 0 | 7 |
| SAR1B | GPR108 | 0.714643 | 3 | 0 | 3 |
| SAR1B | COX15 | 0.710602 | 3 | 0 | 3 |
| SAR1B | ACAA1 | 0.70868 | 9 | 0 | 8 |
| SAR1B | FAM214A | 0.705769 | 5 | 0 | 5 |
| SAR1B | CXCR2 | 0.705575 | 11 | 0 | 11 |
| SAR1B | PITHD1 | 0.705335 | 6 | 0 | 6 |
| SAR1B | FCHO2 | 0.70477 | 8 | 0 | 8 |
| SAR1B | CYSRT1 | 0.704761 | 6 | 0 | 6 |
| SAR1B | CHRNB1 | 0.702471 | 3 | 0 | 3 |
| SAR1B | ITCH | 0.699541 | 12 | 0 | 11 |
| SAR1B | EMC3 | 0.699109 | 11 | 0 | 10 |
| SAR1B | IL20RB | 0.69781 | 6 | 0 | 5 |
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