SYNGR1

 

Full name: synaptogyrin 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 22q13.1
Entrez ID: 9145 HGNC ID: HGNC:11498 Ensembl Gene: ENSG00000100321 OMIM ID: 603925
Drug and gene relationship at DGIdb

 

Expression of SYNGR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SYNGR1 9145 210613_s_at -1.1649 0.0357
GSE20347 SYNGR1 9145 210613_s_at -1.4346 0.0000
GSE23400 SYNGR1 9145 204287_at -0.2623 0.0000
GSE26886 SYNGR1 9145 210613_s_at -1.4502 0.0000
GSE29001 SYNGR1 9145 204287_at -0.4838 0.0942
GSE38129 SYNGR1 9145 210613_s_at -1.2963 0.0000
GSE45670 SYNGR1 9145 210613_s_at -0.6305 0.0172
GSE53622 SYNGR1 9145 15316 -1.4069 0.0000
GSE53624 SYNGR1 9145 15316 -1.4992 0.0000
GSE63941 SYNGR1 9145 210613_s_at -1.6335 0.0098
GSE77861 SYNGR1 9145 210613_s_at -0.7765 0.0339
GSE97050 SYNGR1 9145 A_33_P3284404 -0.5643 0.2841
SRP007169 SYNGR1 9145 RNAseq -2.8557 0.0000
SRP008496 SYNGR1 9145 RNAseq -2.7555 0.0000
SRP064894 SYNGR1 9145 RNAseq -0.7726 0.0202
SRP133303 SYNGR1 9145 RNAseq -1.9773 0.0000
SRP159526 SYNGR1 9145 RNAseq -1.0547 0.0020
SRP193095 SYNGR1 9145 RNAseq -1.4604 0.0000
SRP219564 SYNGR1 9145 RNAseq -1.3213 0.0000
TCGA SYNGR1 9145 RNAseq -0.3758 0.0115

Upregulated datasets: 0; Downregulated datasets: 13.  


 

Survival by SYNGR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SYNGR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SYNGR1 9145 6 5 19
GSE20123 SYNGR1 9145 6 4 20
GSE43470 SYNGR1 9145 5 6 32
GSE46452 SYNGR1 9145 32 2 25
GSE47630 SYNGR1 9145 9 4 27
GSE54993 SYNGR1 9145 4 5 61
GSE54994 SYNGR1 9145 10 7 36
GSE60625 SYNGR1 9145 5 0 6
GSE74703 SYNGR1 9145 5 4 27
GSE74704 SYNGR1 9145 3 2 15
TCGA SYNGR1 9145 27 15 54

Total number of gains: 112; Total number of losses: 54; Total Number of normals: 322.  


 

Somatic mutations of SYNGR1:

 

Generating mutation plots.

 

Highly correlated genes for SYNGR1:

 

Showing top 20/1223 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SYNGR1VSIG10L0.819516606
SYNGR1ANKRD350.792565808
SYNGR1CAPN50.78975910010
SYNGR1SFTA20.786135404
SYNGR1SPINK70.776775606
SYNGR1MGLL0.76265511011
SYNGR1SMDT10.762513404
SYNGR1SPINK50.760678909
SYNGR1TMPRSS11B0.758018606
SYNGR1NUCB20.75726711011
SYNGR1CXCR20.7518210010
SYNGR1FAM214A0.748275606
SYNGR1MYZAP0.745756303
SYNGR1BNIPL0.744515606
SYNGR1PMM10.74208310010
SYNGR1ATP13A40.742044606
SYNGR1GYS20.741398909
SYNGR1RRAGD0.74124210010
SYNGR1GDPD30.7369981009
SYNGR1CCDC120.734633505

For details and further investigation, click here