| Full name: arrestin domain containing 3 | Alias Symbol: KIAA1376|TLIMP | ||
| Type: protein-coding gene | Cytoband: 5q14.3 | ||
| Entrez ID: 57561 | HGNC ID: HGNC:29263 | Ensembl Gene: ENSG00000113369 | OMIM ID: 612464 |
| Drug and gene relationship at DGIdb | |||
Expression of ARRDC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARRDC3 | 57561 | 224797_at | -1.4326 | 0.0466 | |
| GSE26886 | ARRDC3 | 57561 | 224797_at | -2.5276 | 0.0000 | |
| GSE45670 | ARRDC3 | 57561 | 224797_at | -0.1640 | 0.6215 | |
| GSE53622 | ARRDC3 | 57561 | 94734 | -0.9098 | 0.0000 | |
| GSE53624 | ARRDC3 | 57561 | 94734 | -1.2806 | 0.0000 | |
| GSE63941 | ARRDC3 | 57561 | 224797_at | -1.4245 | 0.1094 | |
| GSE77861 | ARRDC3 | 57561 | 224797_at | -1.6723 | 0.0057 | |
| GSE97050 | ARRDC3 | 57561 | A_24_P274615 | -0.4604 | 0.3049 | |
| SRP007169 | ARRDC3 | 57561 | RNAseq | -2.8936 | 0.0000 | |
| SRP008496 | ARRDC3 | 57561 | RNAseq | -2.0017 | 0.0000 | |
| SRP064894 | ARRDC3 | 57561 | RNAseq | -0.7811 | 0.0061 | |
| SRP133303 | ARRDC3 | 57561 | RNAseq | -0.6193 | 0.0004 | |
| SRP159526 | ARRDC3 | 57561 | RNAseq | -1.0948 | 0.0078 | |
| SRP193095 | ARRDC3 | 57561 | RNAseq | -1.4577 | 0.0000 | |
| SRP219564 | ARRDC3 | 57561 | RNAseq | -0.6624 | 0.1726 | |
| TCGA | ARRDC3 | 57561 | RNAseq | -0.1411 | 0.0451 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by ARRDC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARRDC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARRDC3 | 57561 | 1 | 14 | 15 | |
| GSE20123 | ARRDC3 | 57561 | 1 | 14 | 15 | |
| GSE43470 | ARRDC3 | 57561 | 2 | 10 | 31 | |
| GSE46452 | ARRDC3 | 57561 | 0 | 28 | 31 | |
| GSE47630 | ARRDC3 | 57561 | 1 | 20 | 19 | |
| GSE54993 | ARRDC3 | 57561 | 8 | 1 | 61 | |
| GSE54994 | ARRDC3 | 57561 | 1 | 18 | 34 | |
| GSE60625 | ARRDC3 | 57561 | 0 | 0 | 11 | |
| GSE74703 | ARRDC3 | 57561 | 1 | 8 | 27 | |
| GSE74704 | ARRDC3 | 57561 | 1 | 7 | 12 | |
| TCGA | ARRDC3 | 57561 | 2 | 49 | 45 |
Total number of gains: 18; Total number of losses: 169; Total Number of normals: 301.
Somatic mutations of ARRDC3:
Generating mutation plots.
Highly correlated genes for ARRDC3:
Showing top 20/1571 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARRDC3 | SPAG17 | 0.793073 | 4 | 0 | 4 |
| ARRDC3 | IMPACT | 0.789215 | 3 | 0 | 3 |
| ARRDC3 | HMGN1 | 0.787849 | 3 | 0 | 3 |
| ARRDC3 | HBP1 | 0.785496 | 5 | 0 | 5 |
| ARRDC3 | IK | 0.780591 | 7 | 0 | 7 |
| ARRDC3 | FCHO2 | 0.77572 | 8 | 0 | 7 |
| ARRDC3 | SYPL1 | 0.774399 | 3 | 0 | 3 |
| ARRDC3 | FBXW11 | 0.769202 | 7 | 0 | 7 |
| ARRDC3 | CAB39L | 0.765163 | 7 | 0 | 7 |
| ARRDC3 | FCER1A | 0.761269 | 6 | 0 | 6 |
| ARRDC3 | TSHZ2 | 0.761115 | 3 | 0 | 3 |
| ARRDC3 | CHM | 0.761002 | 3 | 0 | 3 |
| ARRDC3 | KDM5D | 0.760053 | 3 | 0 | 3 |
| ARRDC3 | COX15 | 0.75972 | 3 | 0 | 3 |
| ARRDC3 | UBL3 | 0.759302 | 6 | 0 | 6 |
| ARRDC3 | ZNF416 | 0.755241 | 4 | 0 | 4 |
| ARRDC3 | CPT2 | 0.754919 | 5 | 0 | 5 |
| ARRDC3 | RRAGD | 0.754134 | 7 | 0 | 7 |
| ARRDC3 | CCDC6 | 0.753256 | 6 | 0 | 6 |
| ARRDC3 | NAGK | 0.752623 | 7 | 0 | 7 |
For details and further investigation, click here
