| Full name: chromosome 6 open reading frame 141 | Alias Symbol: MGC46457 | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 135398 | HGNC ID: HGNC:21351 | Ensembl Gene: ENSG00000197261 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C6orf141:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C6orf141 | 135398 | 1552575_a_at | 0.5513 | 0.6931 | |
| GSE26886 | C6orf141 | 135398 | 1552575_a_at | 0.1658 | 0.7472 | |
| GSE45670 | C6orf141 | 135398 | 1552575_a_at | 1.2529 | 0.0252 | |
| GSE53622 | C6orf141 | 135398 | 78168 | 0.7138 | 0.0014 | |
| GSE53624 | C6orf141 | 135398 | 78168 | 0.7641 | 0.0000 | |
| GSE63941 | C6orf141 | 135398 | 1552575_a_at | 1.3777 | 0.1053 | |
| GSE77861 | C6orf141 | 135398 | 1552575_a_at | 0.3593 | 0.3282 | |
| GSE97050 | C6orf141 | 135398 | A_33_P3847514 | 0.3891 | 0.1899 | |
| SRP007169 | C6orf141 | 135398 | RNAseq | -0.1766 | 0.7752 | |
| SRP064894 | C6orf141 | 135398 | RNAseq | 1.0514 | 0.0078 | |
| SRP133303 | C6orf141 | 135398 | RNAseq | 1.0916 | 0.0001 | |
| SRP159526 | C6orf141 | 135398 | RNAseq | 0.1886 | 0.8207 | |
| SRP193095 | C6orf141 | 135398 | RNAseq | 0.0740 | 0.7721 | |
| SRP219564 | C6orf141 | 135398 | RNAseq | 0.1932 | 0.8522 | |
| TCGA | C6orf141 | 135398 | RNAseq | 0.6791 | 0.0165 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by C6orf141 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C6orf141:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C6orf141 | 135398 | 4 | 2 | 24 | |
| GSE20123 | C6orf141 | 135398 | 4 | 2 | 24 | |
| GSE43470 | C6orf141 | 135398 | 5 | 0 | 38 | |
| GSE46452 | C6orf141 | 135398 | 2 | 10 | 47 | |
| GSE47630 | C6orf141 | 135398 | 7 | 5 | 28 | |
| GSE54993 | C6orf141 | 135398 | 3 | 1 | 66 | |
| GSE54994 | C6orf141 | 135398 | 8 | 4 | 41 | |
| GSE60625 | C6orf141 | 135398 | 0 | 3 | 8 | |
| GSE74703 | C6orf141 | 135398 | 5 | 0 | 31 | |
| GSE74704 | C6orf141 | 135398 | 1 | 1 | 18 | |
| TCGA | C6orf141 | 135398 | 21 | 12 | 63 |
Total number of gains: 60; Total number of losses: 40; Total Number of normals: 388.
Somatic mutations of C6orf141:
Generating mutation plots.
Highly correlated genes for C6orf141:
Showing top 20/444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C6orf141 | USP40 | 0.840041 | 3 | 0 | 3 |
| C6orf141 | MEF2A | 0.779121 | 3 | 0 | 3 |
| C6orf141 | MTX3 | 0.773196 | 3 | 0 | 3 |
| C6orf141 | COPS8 | 0.7721 | 3 | 0 | 3 |
| C6orf141 | DICER1 | 0.763794 | 3 | 0 | 3 |
| C6orf141 | PSMA4 | 0.76342 | 3 | 0 | 3 |
| C6orf141 | GOPC | 0.760073 | 3 | 0 | 3 |
| C6orf141 | STC2 | 0.755195 | 3 | 0 | 3 |
| C6orf141 | KANK4 | 0.752873 | 4 | 0 | 4 |
| C6orf141 | ITGB1BP1 | 0.743274 | 3 | 0 | 3 |
| C6orf141 | CEP290 | 0.742984 | 3 | 0 | 3 |
| C6orf141 | CBL | 0.742561 | 3 | 0 | 3 |
| C6orf141 | GEMIN6 | 0.741298 | 3 | 0 | 3 |
| C6orf141 | POMGNT1 | 0.73934 | 3 | 0 | 3 |
| C6orf141 | LSM5 | 0.737038 | 3 | 0 | 3 |
| C6orf141 | SPATA5 | 0.730028 | 3 | 0 | 3 |
| C6orf141 | TLR2 | 0.728141 | 3 | 0 | 3 |
| C6orf141 | CHST2 | 0.724274 | 3 | 0 | 3 |
| C6orf141 | MAPK6 | 0.719884 | 3 | 0 | 3 |
| C6orf141 | CXCL16 | 0.71661 | 3 | 0 | 3 |
For details and further investigation, click here
