| Full name: cytochrome b5 reductase 1 | Alias Symbol: humb5R2 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 51706 | HGNC ID: HGNC:13397 | Ensembl Gene: ENSG00000159348 | OMIM ID: 608341 |
| Drug and gene relationship at DGIdb | |||
Expression of CYB5R1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYB5R1 | 51706 | 202263_at | 0.1271 | 0.7927 | |
| GSE20347 | CYB5R1 | 51706 | 202263_at | -0.2530 | 0.2601 | |
| GSE23400 | CYB5R1 | 51706 | 202263_at | 0.1625 | 0.2116 | |
| GSE26886 | CYB5R1 | 51706 | 202263_at | -0.7183 | 0.1006 | |
| GSE29001 | CYB5R1 | 51706 | 202263_at | -0.1803 | 0.6170 | |
| GSE38129 | CYB5R1 | 51706 | 202263_at | -0.1777 | 0.3637 | |
| GSE45670 | CYB5R1 | 51706 | 202263_at | 0.5912 | 0.0386 | |
| GSE53622 | CYB5R1 | 51706 | 64510 | 0.1043 | 0.4376 | |
| GSE53624 | CYB5R1 | 51706 | 64510 | -0.0012 | 0.9925 | |
| GSE63941 | CYB5R1 | 51706 | 202263_at | -1.0123 | 0.1016 | |
| GSE77861 | CYB5R1 | 51706 | 202263_at | -0.0194 | 0.9710 | |
| GSE97050 | CYB5R1 | 51706 | A_23_P52101 | 0.2894 | 0.4650 | |
| SRP007169 | CYB5R1 | 51706 | RNAseq | -0.7268 | 0.1371 | |
| SRP008496 | CYB5R1 | 51706 | RNAseq | -0.9964 | 0.0008 | |
| SRP064894 | CYB5R1 | 51706 | RNAseq | -0.0106 | 0.9540 | |
| SRP133303 | CYB5R1 | 51706 | RNAseq | 0.1020 | 0.7093 | |
| SRP159526 | CYB5R1 | 51706 | RNAseq | -0.4221 | 0.2569 | |
| SRP193095 | CYB5R1 | 51706 | RNAseq | 0.1864 | 0.3664 | |
| SRP219564 | CYB5R1 | 51706 | RNAseq | -0.5466 | 0.1376 | |
| TCGA | CYB5R1 | 51706 | RNAseq | -0.2009 | 0.0151 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYB5R1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYB5R1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYB5R1 | 51706 | 11 | 0 | 19 | |
| GSE20123 | CYB5R1 | 51706 | 11 | 0 | 19 | |
| GSE43470 | CYB5R1 | 51706 | 6 | 0 | 37 | |
| GSE46452 | CYB5R1 | 51706 | 3 | 1 | 55 | |
| GSE47630 | CYB5R1 | 51706 | 14 | 0 | 26 | |
| GSE54993 | CYB5R1 | 51706 | 0 | 6 | 64 | |
| GSE54994 | CYB5R1 | 51706 | 15 | 0 | 38 | |
| GSE60625 | CYB5R1 | 51706 | 0 | 0 | 11 | |
| GSE74703 | CYB5R1 | 51706 | 6 | 0 | 30 | |
| GSE74704 | CYB5R1 | 51706 | 5 | 0 | 15 | |
| TCGA | CYB5R1 | 51706 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of CYB5R1:
Generating mutation plots.
Highly correlated genes for CYB5R1:
Showing top 20/395 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYB5R1 | PRDM4 | 0.754337 | 3 | 0 | 3 |
| CYB5R1 | ADAT1 | 0.744099 | 3 | 0 | 3 |
| CYB5R1 | STEAP1B | 0.741928 | 3 | 0 | 3 |
| CYB5R1 | MTX3 | 0.726081 | 3 | 0 | 3 |
| CYB5R1 | AHCYL2 | 0.721104 | 3 | 0 | 3 |
| CYB5R1 | MTF1 | 0.716717 | 3 | 0 | 3 |
| CYB5R1 | UBLCP1 | 0.704955 | 4 | 0 | 4 |
| CYB5R1 | FAHD1 | 0.700152 | 4 | 0 | 3 |
| CYB5R1 | SNRNP27 | 0.696088 | 3 | 0 | 3 |
| CYB5R1 | DCTN2 | 0.695538 | 3 | 0 | 3 |
| CYB5R1 | LRP11 | 0.693077 | 4 | 0 | 4 |
| CYB5R1 | FAM83G | 0.688272 | 4 | 0 | 4 |
| CYB5R1 | WDR37 | 0.683695 | 4 | 0 | 3 |
| CYB5R1 | NUP153 | 0.681169 | 3 | 0 | 3 |
| CYB5R1 | NCOA4 | 0.680876 | 4 | 0 | 3 |
| CYB5R1 | TMEM167A | 0.680365 | 5 | 0 | 5 |
| CYB5R1 | MTO1 | 0.679769 | 3 | 0 | 3 |
| CYB5R1 | PSMA2 | 0.675323 | 4 | 0 | 3 |
| CYB5R1 | TOMM40L | 0.67395 | 4 | 0 | 3 |
| CYB5R1 | TPCN1 | 0.670799 | 3 | 0 | 3 |
For details and further investigation, click here
