| Full name: Kruppel like factor 10 | Alias Symbol: EGRA|TIEG1 | ||
| Type: protein-coding gene | Cytoband: 8q22.3 | ||
| Entrez ID: 7071 | HGNC ID: HGNC:11810 | Ensembl Gene: ENSG00000155090 | OMIM ID: 601878 |
| Drug and gene relationship at DGIdb | |||
Expression of KLF10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF10 | 7071 | 202393_s_at | -0.1054 | 0.9089 | |
| GSE20347 | KLF10 | 7071 | 202393_s_at | 0.4701 | 0.1516 | |
| GSE23400 | KLF10 | 7071 | 202393_s_at | 0.6570 | 0.0000 | |
| GSE26886 | KLF10 | 7071 | 202393_s_at | 1.1075 | 0.0003 | |
| GSE29001 | KLF10 | 7071 | 202393_s_at | 0.6396 | 0.1165 | |
| GSE38129 | KLF10 | 7071 | 202393_s_at | 0.2570 | 0.3411 | |
| GSE45670 | KLF10 | 7071 | 202393_s_at | 0.2589 | 0.3784 | |
| GSE63941 | KLF10 | 7071 | 202393_s_at | -0.2115 | 0.7340 | |
| GSE77861 | KLF10 | 7071 | 202393_s_at | 0.9208 | 0.1015 | |
| GSE97050 | KLF10 | 7071 | A_23_P168828 | -0.2823 | 0.6890 | |
| SRP007169 | KLF10 | 7071 | RNAseq | 0.9710 | 0.0754 | |
| SRP008496 | KLF10 | 7071 | RNAseq | 1.7416 | 0.0000 | |
| SRP064894 | KLF10 | 7071 | RNAseq | 0.4191 | 0.1174 | |
| SRP133303 | KLF10 | 7071 | RNAseq | 0.8696 | 0.0007 | |
| SRP159526 | KLF10 | 7071 | RNAseq | -0.3709 | 0.3479 | |
| SRP193095 | KLF10 | 7071 | RNAseq | 1.0032 | 0.0000 | |
| SRP219564 | KLF10 | 7071 | RNAseq | -0.2671 | 0.6435 | |
| TCGA | KLF10 | 7071 | RNAseq | -0.0820 | 0.2671 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by KLF10 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KLF10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF10 | 7071 | 17 | 0 | 13 | |
| GSE20123 | KLF10 | 7071 | 18 | 0 | 12 | |
| GSE43470 | KLF10 | 7071 | 22 | 0 | 21 | |
| GSE46452 | KLF10 | 7071 | 24 | 0 | 35 | |
| GSE47630 | KLF10 | 7071 | 24 | 0 | 16 | |
| GSE54993 | KLF10 | 7071 | 0 | 20 | 50 | |
| GSE54994 | KLF10 | 7071 | 38 | 1 | 14 | |
| GSE60625 | KLF10 | 7071 | 0 | 4 | 7 | |
| GSE74703 | KLF10 | 7071 | 19 | 0 | 17 | |
| GSE74704 | KLF10 | 7071 | 12 | 0 | 8 | |
| TCGA | KLF10 | 7071 | 59 | 1 | 36 |
Total number of gains: 233; Total number of losses: 26; Total Number of normals: 229.
Somatic mutations of KLF10:
Generating mutation plots.
Highly correlated genes for KLF10:
Showing top 20/767 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF10 | MBNL1 | 0.786356 | 3 | 0 | 3 |
| KLF10 | ZNF827 | 0.78466 | 3 | 0 | 3 |
| KLF10 | JDP2 | 0.757822 | 3 | 0 | 3 |
| KLF10 | FBLIM1 | 0.752941 | 4 | 0 | 4 |
| KLF10 | RSRC1 | 0.747928 | 3 | 0 | 3 |
| KLF10 | PDE6D | 0.741276 | 3 | 0 | 3 |
| KLF10 | SPIRE1 | 0.741022 | 5 | 0 | 4 |
| KLF10 | IAH1 | 0.720851 | 3 | 0 | 3 |
| KLF10 | COX7A1 | 0.720425 | 3 | 0 | 3 |
| KLF10 | MYADM | 0.717743 | 4 | 0 | 4 |
| KLF10 | SMIM3 | 0.71595 | 4 | 0 | 4 |
| KLF10 | ZBTB8A | 0.713102 | 3 | 0 | 3 |
| KLF10 | MTX3 | 0.706882 | 3 | 0 | 3 |
| KLF10 | ZFHX3 | 0.703369 | 3 | 0 | 3 |
| KLF10 | TNS4 | 0.699133 | 3 | 0 | 3 |
| KLF10 | HERPUD2 | 0.697631 | 3 | 0 | 3 |
| KLF10 | PEAR1 | 0.697105 | 3 | 0 | 3 |
| KLF10 | SF3B2 | 0.696588 | 3 | 0 | 3 |
| KLF10 | DYNC1LI2 | 0.696175 | 4 | 0 | 3 |
| KLF10 | ALKBH6 | 0.684034 | 3 | 0 | 3 |
For details and further investigation, click here
