| Full name: dehydrogenase/reductase 7 | Alias Symbol: retDSR4|SDR34C1 | ||
| Type: protein-coding gene | Cytoband: 14q23.1 | ||
| Entrez ID: 51635 | HGNC ID: HGNC:21524 | Ensembl Gene: ENSG00000100612 | OMIM ID: 612833 |
| Drug and gene relationship at DGIdb | |||
Expression of DHRS7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHRS7 | 51635 | 210788_s_at | -0.2054 | 0.7894 | |
| GSE20347 | DHRS7 | 51635 | 210788_s_at | -0.4355 | 0.0443 | |
| GSE23400 | DHRS7 | 51635 | 210788_s_at | 0.0844 | 0.4259 | |
| GSE26886 | DHRS7 | 51635 | 210788_s_at | -0.1577 | 0.5908 | |
| GSE29001 | DHRS7 | 51635 | 210788_s_at | -0.2760 | 0.4221 | |
| GSE38129 | DHRS7 | 51635 | 210788_s_at | -0.2399 | 0.1590 | |
| GSE45670 | DHRS7 | 51635 | 210788_s_at | 0.2426 | 0.3129 | |
| GSE53622 | DHRS7 | 51635 | 2016 | 0.1497 | 0.3768 | |
| GSE53624 | DHRS7 | 51635 | 2016 | 0.0077 | 0.9384 | |
| GSE63941 | DHRS7 | 51635 | 210788_s_at | -0.0198 | 0.9732 | |
| GSE77861 | DHRS7 | 51635 | 210788_s_at | -0.0044 | 0.9928 | |
| GSE97050 | DHRS7 | 51635 | A_23_P117506 | 0.3438 | 0.1886 | |
| SRP007169 | DHRS7 | 51635 | RNAseq | -1.1709 | 0.0009 | |
| SRP008496 | DHRS7 | 51635 | RNAseq | -0.4400 | 0.1286 | |
| SRP064894 | DHRS7 | 51635 | RNAseq | 0.4308 | 0.0440 | |
| SRP133303 | DHRS7 | 51635 | RNAseq | 0.1998 | 0.1672 | |
| SRP159526 | DHRS7 | 51635 | RNAseq | -0.2224 | 0.4815 | |
| SRP193095 | DHRS7 | 51635 | RNAseq | -0.2322 | 0.3184 | |
| SRP219564 | DHRS7 | 51635 | RNAseq | 0.1278 | 0.7235 | |
| TCGA | DHRS7 | 51635 | RNAseq | -0.3555 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DHRS7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHRS7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHRS7 | 51635 | 8 | 3 | 19 | |
| GSE20123 | DHRS7 | 51635 | 7 | 3 | 20 | |
| GSE43470 | DHRS7 | 51635 | 8 | 2 | 33 | |
| GSE46452 | DHRS7 | 51635 | 16 | 3 | 40 | |
| GSE47630 | DHRS7 | 51635 | 11 | 9 | 20 | |
| GSE54993 | DHRS7 | 51635 | 3 | 9 | 58 | |
| GSE54994 | DHRS7 | 51635 | 19 | 4 | 30 | |
| GSE60625 | DHRS7 | 51635 | 0 | 2 | 9 | |
| GSE74703 | DHRS7 | 51635 | 7 | 2 | 27 | |
| GSE74704 | DHRS7 | 51635 | 3 | 2 | 15 | |
| TCGA | DHRS7 | 51635 | 32 | 14 | 50 |
Total number of gains: 114; Total number of losses: 53; Total Number of normals: 321.
Somatic mutations of DHRS7:
Generating mutation plots.
Highly correlated genes for DHRS7:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHRS7 | MTX3 | 0.798963 | 4 | 0 | 4 |
| DHRS7 | USP32 | 0.793763 | 3 | 0 | 3 |
| DHRS7 | PRRC1 | 0.754331 | 3 | 0 | 3 |
| DHRS7 | LZIC | 0.753005 | 3 | 0 | 3 |
| DHRS7 | DCTN4 | 0.749806 | 4 | 0 | 3 |
| DHRS7 | CD109 | 0.736439 | 3 | 0 | 3 |
| DHRS7 | MTSS1 | 0.733701 | 3 | 0 | 3 |
| DHRS7 | TTC8 | 0.732221 | 4 | 0 | 4 |
| DHRS7 | P4HA1 | 0.727783 | 3 | 0 | 3 |
| DHRS7 | POLR3GL | 0.727755 | 3 | 0 | 3 |
| DHRS7 | USP40 | 0.720983 | 3 | 0 | 3 |
| DHRS7 | MRPS27 | 0.698959 | 5 | 0 | 4 |
| DHRS7 | AFAP1L2 | 0.695797 | 4 | 0 | 4 |
| DHRS7 | DQX1 | 0.694726 | 3 | 0 | 3 |
| DHRS7 | FBLIM1 | 0.694386 | 3 | 0 | 3 |
| DHRS7 | TERF2IP | 0.694232 | 3 | 0 | 3 |
| DHRS7 | PCM1 | 0.690245 | 3 | 0 | 3 |
| DHRS7 | ZFYVE16 | 0.688706 | 4 | 0 | 3 |
| DHRS7 | CHMP4B | 0.688354 | 3 | 0 | 3 |
| DHRS7 | HSPA9 | 0.684643 | 4 | 0 | 3 |
For details and further investigation, click here
