| Full name: myosin heavy chain 13 | Alias Symbol: MyHC-eo | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 8735 | HGNC ID: HGNC:7571 | Ensembl Gene: ENSG00000006788 | OMIM ID: 603487 |
| Drug and gene relationship at DGIdb | |||
MYH13 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of MYH13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYH13 | 8735 | 208208_at | -0.1111 | 0.6818 | |
| GSE20347 | MYH13 | 8735 | 208208_at | -0.0057 | 0.9407 | |
| GSE23400 | MYH13 | 8735 | 208208_at | -0.2236 | 0.0000 | |
| GSE26886 | MYH13 | 8735 | 208208_at | 0.0274 | 0.8997 | |
| GSE29001 | MYH13 | 8735 | 208208_at | -0.2893 | 0.1643 | |
| GSE38129 | MYH13 | 8735 | 208208_at | -0.0624 | 0.3517 | |
| GSE45670 | MYH13 | 8735 | 208208_at | -0.0075 | 0.9478 | |
| GSE63941 | MYH13 | 8735 | 208208_at | 0.3022 | 0.1729 | |
| GSE77861 | MYH13 | 8735 | 208208_at | -0.2192 | 0.1118 | |
| GSE97050 | MYH13 | 8735 | A_23_P89334 | -0.1486 | 0.5091 | |
| TCGA | MYH13 | 8735 | RNAseq | -3.0587 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MYH13 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MYH13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYH13 | 8735 | 2 | 4 | 24 | |
| GSE20123 | MYH13 | 8735 | 2 | 5 | 23 | |
| GSE43470 | MYH13 | 8735 | 2 | 6 | 35 | |
| GSE46452 | MYH13 | 8735 | 34 | 1 | 24 | |
| GSE47630 | MYH13 | 8735 | 7 | 1 | 32 | |
| GSE54993 | MYH13 | 8735 | 4 | 3 | 63 | |
| GSE54994 | MYH13 | 8735 | 5 | 8 | 40 | |
| GSE60625 | MYH13 | 8735 | 4 | 0 | 7 | |
| GSE74703 | MYH13 | 8735 | 2 | 4 | 30 | |
| GSE74704 | MYH13 | 8735 | 1 | 2 | 17 | |
| TCGA | MYH13 | 8735 | 17 | 20 | 59 |
Total number of gains: 80; Total number of losses: 54; Total Number of normals: 354.
Somatic mutations of MYH13:
Generating mutation plots.
Highly correlated genes for MYH13:
Showing top 20/444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYH13 | CD300LG | 0.735882 | 3 | 0 | 3 |
| MYH13 | CRTAC1 | 0.726952 | 5 | 0 | 5 |
| MYH13 | PROCA1 | 0.725639 | 3 | 0 | 3 |
| MYH13 | BTBD19 | 0.721497 | 3 | 0 | 3 |
| MYH13 | NPPC | 0.720069 | 3 | 0 | 3 |
| MYH13 | CDH22 | 0.719364 | 3 | 0 | 3 |
| MYH13 | THRSP | 0.71402 | 4 | 0 | 4 |
| MYH13 | BEAN1 | 0.709922 | 3 | 0 | 3 |
| MYH13 | TGM6 | 0.706559 | 3 | 0 | 3 |
| MYH13 | CATSPER3 | 0.701353 | 4 | 0 | 3 |
| MYH13 | TEF | 0.694294 | 3 | 0 | 3 |
| MYH13 | OPRD1 | 0.69076 | 5 | 0 | 4 |
| MYH13 | DHH | 0.690193 | 4 | 0 | 3 |
| MYH13 | KCNK5 | 0.689489 | 3 | 0 | 3 |
| MYH13 | HECW1 | 0.686283 | 4 | 0 | 3 |
| MYH13 | ARHGAP30 | 0.684065 | 4 | 0 | 3 |
| MYH13 | FZD9 | 0.682251 | 3 | 0 | 3 |
| MYH13 | LELP1 | 0.680645 | 3 | 0 | 3 |
| MYH13 | MC3R | 0.67883 | 4 | 0 | 3 |
| MYH13 | LINC00302 | 0.672276 | 3 | 0 | 3 |
For details and further investigation, click here
