| Full name: N-acetylated alpha-linked acidic dipeptidase like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 10004 | HGNC ID: HGNC:23536 | Ensembl Gene: ENSG00000168060 | OMIM ID: 602640 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NAALADL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAALADL1 | 10004 | 228424_at | -0.3151 | 0.2836 | |
| GSE20347 | NAALADL1 | 10004 | 207895_at | 0.0582 | 0.4419 | |
| GSE23400 | NAALADL1 | 10004 | 207895_at | -0.0980 | 0.0062 | |
| GSE26886 | NAALADL1 | 10004 | 228424_at | 0.0498 | 0.7605 | |
| GSE29001 | NAALADL1 | 10004 | 207895_at | -0.0486 | 0.7599 | |
| GSE38129 | NAALADL1 | 10004 | 207895_at | -0.0906 | 0.5267 | |
| GSE45670 | NAALADL1 | 10004 | 228424_at | -0.2915 | 0.0022 | |
| GSE53622 | NAALADL1 | 10004 | 446 | -0.5131 | 0.0000 | |
| GSE53624 | NAALADL1 | 10004 | 446 | -0.2483 | 0.0019 | |
| GSE63941 | NAALADL1 | 10004 | 228424_at | -0.6833 | 0.0010 | |
| GSE77861 | NAALADL1 | 10004 | 228424_at | -0.1507 | 0.1920 | |
| GSE97050 | NAALADL1 | 10004 | A_23_P52668 | -0.1415 | 0.5960 | |
| SRP007169 | NAALADL1 | 10004 | RNAseq | 0.5540 | 0.5088 | |
| SRP064894 | NAALADL1 | 10004 | RNAseq | 0.0048 | 0.9905 | |
| SRP133303 | NAALADL1 | 10004 | RNAseq | -0.2013 | 0.4848 | |
| SRP159526 | NAALADL1 | 10004 | RNAseq | -1.4022 | 0.0001 | |
| SRP219564 | NAALADL1 | 10004 | RNAseq | -0.8518 | 0.2235 | |
| TCGA | NAALADL1 | 10004 | RNAseq | -0.3313 | 0.1042 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NAALADL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAALADL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAALADL1 | 10004 | 7 | 6 | 17 | |
| GSE20123 | NAALADL1 | 10004 | 7 | 6 | 17 | |
| GSE43470 | NAALADL1 | 10004 | 2 | 3 | 38 | |
| GSE46452 | NAALADL1 | 10004 | 10 | 4 | 45 | |
| GSE47630 | NAALADL1 | 10004 | 5 | 6 | 29 | |
| GSE54993 | NAALADL1 | 10004 | 3 | 0 | 67 | |
| GSE54994 | NAALADL1 | 10004 | 6 | 5 | 42 | |
| GSE60625 | NAALADL1 | 10004 | 0 | 3 | 8 | |
| GSE74703 | NAALADL1 | 10004 | 2 | 1 | 33 | |
| GSE74704 | NAALADL1 | 10004 | 5 | 4 | 11 | |
| TCGA | NAALADL1 | 10004 | 23 | 7 | 66 |
Total number of gains: 70; Total number of losses: 45; Total Number of normals: 373.
Somatic mutations of NAALADL1:
Generating mutation plots.
Highly correlated genes for NAALADL1:
Showing top 20/968 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAALADL1 | C11orf96 | 0.804815 | 3 | 0 | 3 |
| NAALADL1 | CCDC102B | 0.760203 | 3 | 0 | 3 |
| NAALADL1 | FNIP2 | 0.755455 | 3 | 0 | 3 |
| NAALADL1 | MAPRE3 | 0.745349 | 3 | 0 | 3 |
| NAALADL1 | HRH2 | 0.742309 | 4 | 0 | 4 |
| NAALADL1 | FATE1 | 0.738586 | 3 | 0 | 3 |
| NAALADL1 | LINC01279 | 0.734025 | 3 | 0 | 3 |
| NAALADL1 | GRK5 | 0.724063 | 5 | 0 | 5 |
| NAALADL1 | CD200 | 0.723748 | 4 | 0 | 4 |
| NAALADL1 | S1PR3 | 0.723519 | 4 | 0 | 4 |
| NAALADL1 | KRTAP1-3 | 0.714754 | 4 | 0 | 4 |
| NAALADL1 | SPIN2A | 0.713921 | 3 | 0 | 3 |
| NAALADL1 | AMBN | 0.709771 | 3 | 0 | 3 |
| NAALADL1 | HDX | 0.709163 | 4 | 0 | 4 |
| NAALADL1 | CAPN11 | 0.708498 | 3 | 0 | 3 |
| NAALADL1 | AFF3 | 0.705449 | 4 | 0 | 3 |
| NAALADL1 | SGIP1 | 0.704427 | 4 | 0 | 4 |
| NAALADL1 | WDR63 | 0.703395 | 3 | 0 | 3 |
| NAALADL1 | DCHS1 | 0.699731 | 6 | 0 | 4 |
| NAALADL1 | NEK1 | 0.699235 | 3 | 0 | 3 |
For details and further investigation, click here
