| Full name: nanos C2HC-type zinc finger 1 | Alias Symbol: NOS1|ZC2HC12A | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 340719 | HGNC ID: HGNC:23044 | Ensembl Gene: ENSG00000188613 | OMIM ID: 608226 |
| Drug and gene relationship at DGIdb | |||
Expression of NANOS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE26886 | NANOS1 | 340719 | 228523_at | 1.2976 | 0.0059 | |
| GSE45670 | NANOS1 | 340719 | 228523_at | 1.4921 | 0.0017 | |
| GSE53622 | NANOS1 | 340719 | 64100 | 0.2678 | 0.1248 | |
| GSE53624 | NANOS1 | 340719 | 64100 | 0.8748 | 0.0000 | |
| GSE63941 | NANOS1 | 340719 | 228523_at | 1.1455 | 0.2394 | |
| GSE97050 | NANOS1 | 340719 | A_24_P383609 | -0.0759 | 0.8010 | |
| SRP007169 | NANOS1 | 340719 | RNAseq | -0.7219 | 0.2319 | |
| SRP064894 | NANOS1 | 340719 | RNAseq | 0.8085 | 0.0046 | |
| SRP133303 | NANOS1 | 340719 | RNAseq | 0.7809 | 0.0382 | |
| SRP159526 | NANOS1 | 340719 | RNAseq | 1.1186 | 0.0395 | |
| SRP193095 | NANOS1 | 340719 | RNAseq | 0.6248 | 0.0000 | |
| TCGA | NANOS1 | 340719 | RNAseq | -0.0904 | 0.3585 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NANOS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NANOS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NANOS1 | 340719 | 2 | 7 | 21 | |
| GSE20123 | NANOS1 | 340719 | 2 | 7 | 21 | |
| GSE43470 | NANOS1 | 340719 | 0 | 9 | 34 | |
| GSE46452 | NANOS1 | 340719 | 0 | 11 | 48 | |
| GSE47630 | NANOS1 | 340719 | 2 | 14 | 24 | |
| GSE54993 | NANOS1 | 340719 | 8 | 0 | 62 | |
| GSE54994 | NANOS1 | 340719 | 1 | 9 | 43 | |
| GSE60625 | NANOS1 | 340719 | 0 | 0 | 11 | |
| GSE74703 | NANOS1 | 340719 | 0 | 6 | 30 | |
| GSE74704 | NANOS1 | 340719 | 1 | 3 | 16 | |
| TCGA | NANOS1 | 340719 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 94; Total Number of normals: 374.
Somatic mutations of NANOS1:
Generating mutation plots.
Highly correlated genes for NANOS1:
Showing top 20/305 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NANOS1 | STK17A | 0.829215 | 3 | 0 | 3 |
| NANOS1 | MFF | 0.759738 | 3 | 0 | 3 |
| NANOS1 | SLC7A6OS | 0.745298 | 3 | 0 | 3 |
| NANOS1 | PSMD1 | 0.744419 | 3 | 0 | 3 |
| NANOS1 | RPL7L1 | 0.719342 | 3 | 0 | 3 |
| NANOS1 | VEZT | 0.718679 | 3 | 0 | 3 |
| NANOS1 | SLC9A1 | 0.718626 | 3 | 0 | 3 |
| NANOS1 | RPL26L1 | 0.714898 | 3 | 0 | 3 |
| NANOS1 | RPF1 | 0.713144 | 3 | 0 | 3 |
| NANOS1 | PTPN12 | 0.705441 | 3 | 0 | 3 |
| NANOS1 | TNPO1 | 0.704356 | 3 | 0 | 3 |
| NANOS1 | BCL7C | 0.700539 | 3 | 0 | 3 |
| NANOS1 | NAP1L4 | 0.697688 | 3 | 0 | 3 |
| NANOS1 | ABCF1 | 0.696514 | 3 | 0 | 3 |
| NANOS1 | ZNF484 | 0.696033 | 4 | 0 | 4 |
| NANOS1 | EPPK1 | 0.695852 | 4 | 0 | 4 |
| NANOS1 | TTC26 | 0.69445 | 3 | 0 | 3 |
| NANOS1 | SFR1 | 0.69342 | 3 | 0 | 3 |
| NANOS1 | MRPL32 | 0.691547 | 4 | 0 | 3 |
| NANOS1 | SDHAF2 | 0.691242 | 3 | 0 | 3 |
For details and further investigation, click here
