| Full name: serine/threonine kinase 17a | Alias Symbol: DRAK1 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 9263 | HGNC ID: HGNC:11395 | Ensembl Gene: ENSG00000164543 | OMIM ID: 604726 |
| Drug and gene relationship at DGIdb | |||
Expression of STK17A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK17A | 9263 | 202693_s_at | 0.5330 | 0.4819 | |
| GSE20347 | STK17A | 9263 | 202693_s_at | 0.8138 | 0.0126 | |
| GSE23400 | STK17A | 9263 | 202693_s_at | 0.7746 | 0.0000 | |
| GSE26886 | STK17A | 9263 | 202693_s_at | 1.5580 | 0.0004 | |
| GSE29001 | STK17A | 9263 | 202693_s_at | 0.5402 | 0.3010 | |
| GSE38129 | STK17A | 9263 | 202693_s_at | 0.8980 | 0.0004 | |
| GSE45670 | STK17A | 9263 | 202693_s_at | 0.9929 | 0.0021 | |
| GSE63941 | STK17A | 9263 | 202693_s_at | -0.1290 | 0.8575 | |
| GSE77861 | STK17A | 9263 | 202693_s_at | 1.2769 | 0.0388 | |
| GSE97050 | STK17A | 9263 | A_33_P3229467 | 0.0238 | 0.9440 | |
| SRP007169 | STK17A | 9263 | RNAseq | 0.6823 | 0.1959 | |
| SRP008496 | STK17A | 9263 | RNAseq | 0.6407 | 0.0334 | |
| SRP064894 | STK17A | 9263 | RNAseq | 0.4782 | 0.0255 | |
| SRP133303 | STK17A | 9263 | RNAseq | 1.0241 | 0.0000 | |
| SRP159526 | STK17A | 9263 | RNAseq | 0.6255 | 0.1893 | |
| SRP193095 | STK17A | 9263 | RNAseq | 0.7263 | 0.0000 | |
| SRP219564 | STK17A | 9263 | RNAseq | 0.3165 | 0.6018 | |
| TCGA | STK17A | 9263 | RNAseq | 0.1126 | 0.1384 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by STK17A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of STK17A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK17A | 9263 | 14 | 0 | 16 | |
| GSE20123 | STK17A | 9263 | 13 | 0 | 17 | |
| GSE43470 | STK17A | 9263 | 4 | 0 | 39 | |
| GSE46452 | STK17A | 9263 | 11 | 1 | 47 | |
| GSE47630 | STK17A | 9263 | 8 | 1 | 31 | |
| GSE54993 | STK17A | 9263 | 0 | 8 | 62 | |
| GSE54994 | STK17A | 9263 | 17 | 3 | 33 | |
| GSE60625 | STK17A | 9263 | 0 | 0 | 11 | |
| GSE74703 | STK17A | 9263 | 4 | 0 | 32 | |
| GSE74704 | STK17A | 9263 | 7 | 0 | 13 | |
| TCGA | STK17A | 9263 | 50 | 7 | 39 |
Total number of gains: 128; Total number of losses: 20; Total Number of normals: 340.
Somatic mutations of STK17A:
Generating mutation plots.
Highly correlated genes for STK17A:
Showing top 20/1169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK17A | NANOS1 | 0.829215 | 3 | 0 | 3 |
| STK17A | PPP6R3 | 0.796487 | 3 | 0 | 3 |
| STK17A | PPP1R21 | 0.796069 | 3 | 0 | 3 |
| STK17A | ST3GAL2 | 0.788641 | 3 | 0 | 3 |
| STK17A | CYP27C1 | 0.786532 | 5 | 0 | 5 |
| STK17A | METTL23 | 0.777658 | 3 | 0 | 3 |
| STK17A | SLC15A4 | 0.774869 | 3 | 0 | 3 |
| STK17A | KLHL13 | 0.762245 | 3 | 0 | 3 |
| STK17A | ANO6 | 0.759908 | 3 | 0 | 3 |
| STK17A | B3GALT6 | 0.757254 | 3 | 0 | 3 |
| STK17A | PDE6D | 0.755339 | 3 | 0 | 3 |
| STK17A | USP40 | 0.755169 | 3 | 0 | 3 |
| STK17A | RRP36 | 0.747051 | 3 | 0 | 3 |
| STK17A | CCM2 | 0.742249 | 5 | 0 | 5 |
| STK17A | PPHLN1 | 0.740797 | 3 | 0 | 3 |
| STK17A | PET117 | 0.738075 | 3 | 0 | 3 |
| STK17A | SLC6A6 | 0.737998 | 3 | 0 | 3 |
| STK17A | DOCK11 | 0.732534 | 3 | 0 | 3 |
| STK17A | CERCAM | 0.73032 | 4 | 0 | 4 |
| STK17A | ANKRD10 | 0.72979 | 3 | 0 | 3 |
For details and further investigation, click here
