| Full name: mitochondrial ribosomal protein L32 | Alias Symbol: HSPC283|L32mt|MRP-L32|bMRP-59b | ||
| Type: protein-coding gene | Cytoband: 7p14.1 | ||
| Entrez ID: 64983 | HGNC ID: HGNC:14035 | Ensembl Gene: ENSG00000106591 | OMIM ID: 611839 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL32 | 64983 | 225260_s_at | 0.1667 | 0.7849 | |
| GSE26886 | MRPL32 | 64983 | 225260_s_at | 0.8215 | 0.0000 | |
| GSE45670 | MRPL32 | 64983 | 225260_s_at | 0.3816 | 0.0053 | |
| GSE53622 | MRPL32 | 64983 | 127928 | 0.3986 | 0.0000 | |
| GSE53624 | MRPL32 | 64983 | 127928 | 0.6948 | 0.0000 | |
| GSE63941 | MRPL32 | 64983 | 225260_s_at | 0.2554 | 0.5261 | |
| GSE77861 | MRPL32 | 64983 | 225260_s_at | 0.2813 | 0.4413 | |
| GSE97050 | MRPL32 | 64983 | A_23_P111753 | 0.1347 | 0.4893 | |
| SRP007169 | MRPL32 | 64983 | RNAseq | 0.1230 | 0.7485 | |
| SRP008496 | MRPL32 | 64983 | RNAseq | 0.5325 | 0.0489 | |
| SRP064894 | MRPL32 | 64983 | RNAseq | 0.3180 | 0.0463 | |
| SRP133303 | MRPL32 | 64983 | RNAseq | 0.6489 | 0.0000 | |
| SRP159526 | MRPL32 | 64983 | RNAseq | 0.0596 | 0.8067 | |
| SRP193095 | MRPL32 | 64983 | RNAseq | -0.0186 | 0.8938 | |
| SRP219564 | MRPL32 | 64983 | RNAseq | 0.0444 | 0.8917 | |
| TCGA | MRPL32 | 64983 | RNAseq | 0.0023 | 0.9678 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL32 | 64983 | 14 | 0 | 16 | |
| GSE20123 | MRPL32 | 64983 | 13 | 0 | 17 | |
| GSE43470 | MRPL32 | 64983 | 4 | 0 | 39 | |
| GSE46452 | MRPL32 | 64983 | 11 | 1 | 47 | |
| GSE47630 | MRPL32 | 64983 | 8 | 1 | 31 | |
| GSE54993 | MRPL32 | 64983 | 0 | 7 | 63 | |
| GSE54994 | MRPL32 | 64983 | 17 | 3 | 33 | |
| GSE60625 | MRPL32 | 64983 | 0 | 0 | 11 | |
| GSE74703 | MRPL32 | 64983 | 4 | 0 | 32 | |
| GSE74704 | MRPL32 | 64983 | 7 | 0 | 13 | |
| TCGA | MRPL32 | 64983 | 50 | 7 | 39 |
Total number of gains: 128; Total number of losses: 19; Total Number of normals: 341.
Somatic mutations of MRPL32:
Generating mutation plots.
Highly correlated genes for MRPL32:
Showing top 20/1295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL32 | RBM17 | 0.795019 | 3 | 0 | 3 |
| MRPL32 | GTF2H3 | 0.777748 | 3 | 0 | 3 |
| MRPL32 | NPHP3 | 0.763064 | 3 | 0 | 3 |
| MRPL32 | ECSIT | 0.762685 | 3 | 0 | 3 |
| MRPL32 | TM2D3 | 0.752302 | 3 | 0 | 3 |
| MRPL32 | PPP1R21 | 0.751779 | 3 | 0 | 3 |
| MRPL32 | SEC11A | 0.750319 | 4 | 0 | 4 |
| MRPL32 | METAP2 | 0.749318 | 4 | 0 | 4 |
| MRPL32 | CMC1 | 0.748633 | 3 | 0 | 3 |
| MRPL32 | RBMX | 0.742691 | 3 | 0 | 3 |
| MRPL32 | POSTN | 0.736779 | 3 | 0 | 3 |
| MRPL32 | METTL23 | 0.736073 | 5 | 0 | 5 |
| MRPL32 | IGF2R | 0.733868 | 3 | 0 | 3 |
| MRPL32 | NEDD8 | 0.733731 | 4 | 0 | 3 |
| MRPL32 | MED17 | 0.72912 | 3 | 0 | 3 |
| MRPL32 | LIMS1 | 0.728679 | 3 | 0 | 3 |
| MRPL32 | ZNF200 | 0.72778 | 3 | 0 | 3 |
| MRPL32 | BANF1 | 0.72695 | 5 | 0 | 5 |
| MRPL32 | GCSH | 0.724364 | 3 | 0 | 3 |
| MRPL32 | SDR39U1 | 0.722422 | 3 | 0 | 3 |
For details and further investigation, click here
