| Full name: ribosome production factor 1 homolog | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 80135 | HGNC ID: HGNC:30350 | Ensembl Gene: ENSG00000117133 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPF1 | 80135 | 218462_at | -0.0018 | 0.9966 | |
| GSE20347 | RPF1 | 80135 | 218462_at | 0.1385 | 0.4203 | |
| GSE23400 | RPF1 | 80135 | 218462_at | 0.3672 | 0.0000 | |
| GSE26886 | RPF1 | 80135 | 218462_at | -0.3803 | 0.1423 | |
| GSE29001 | RPF1 | 80135 | 218462_at | 0.3725 | 0.1149 | |
| GSE38129 | RPF1 | 80135 | 218462_at | 0.2291 | 0.0646 | |
| GSE45670 | RPF1 | 80135 | 218462_at | 0.1344 | 0.3247 | |
| GSE53622 | RPF1 | 80135 | 102562 | 0.0549 | 0.3926 | |
| GSE53624 | RPF1 | 80135 | 102562 | 0.2803 | 0.0000 | |
| GSE63941 | RPF1 | 80135 | 218462_at | 0.7430 | 0.0444 | |
| GSE77861 | RPF1 | 80135 | 218462_at | 0.0800 | 0.7780 | |
| GSE97050 | RPF1 | 80135 | A_23_P359616 | -0.0394 | 0.8918 | |
| SRP007169 | RPF1 | 80135 | RNAseq | 0.7706 | 0.1135 | |
| SRP008496 | RPF1 | 80135 | RNAseq | 0.5921 | 0.0885 | |
| SRP064894 | RPF1 | 80135 | RNAseq | 0.2101 | 0.1779 | |
| SRP133303 | RPF1 | 80135 | RNAseq | 0.1704 | 0.3864 | |
| SRP159526 | RPF1 | 80135 | RNAseq | -0.4082 | 0.1080 | |
| SRP193095 | RPF1 | 80135 | RNAseq | -0.2755 | 0.0185 | |
| SRP219564 | RPF1 | 80135 | RNAseq | 0.2833 | 0.4147 | |
| TCGA | RPF1 | 80135 | RNAseq | 0.0825 | 0.1252 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPF1 | 80135 | 0 | 8 | 22 | |
| GSE20123 | RPF1 | 80135 | 0 | 8 | 22 | |
| GSE43470 | RPF1 | 80135 | 2 | 2 | 39 | |
| GSE46452 | RPF1 | 80135 | 0 | 1 | 58 | |
| GSE47630 | RPF1 | 80135 | 8 | 5 | 27 | |
| GSE54993 | RPF1 | 80135 | 0 | 0 | 70 | |
| GSE54994 | RPF1 | 80135 | 6 | 3 | 44 | |
| GSE60625 | RPF1 | 80135 | 0 | 0 | 11 | |
| GSE74703 | RPF1 | 80135 | 1 | 2 | 33 | |
| GSE74704 | RPF1 | 80135 | 0 | 5 | 15 | |
| TCGA | RPF1 | 80135 | 7 | 23 | 66 |
Total number of gains: 24; Total number of losses: 57; Total Number of normals: 407.
Somatic mutations of RPF1:
Generating mutation plots.
Highly correlated genes for RPF1:
Showing top 20/639 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPF1 | MYSM1 | 0.737639 | 3 | 0 | 3 |
| RPF1 | NAA30 | 0.733645 | 3 | 0 | 3 |
| RPF1 | RSRC2 | 0.71717 | 4 | 0 | 3 |
| RPF1 | ETF1 | 0.715758 | 3 | 0 | 3 |
| RPF1 | NANOS1 | 0.713144 | 3 | 0 | 3 |
| RPF1 | PCNP | 0.708648 | 3 | 0 | 3 |
| RPF1 | SPATA5 | 0.706431 | 3 | 0 | 3 |
| RPF1 | C15orf61 | 0.702165 | 3 | 0 | 3 |
| RPF1 | SFR1 | 0.698594 | 3 | 0 | 3 |
| RPF1 | IER3IP1 | 0.696752 | 3 | 0 | 3 |
| RPF1 | C12orf57 | 0.691233 | 4 | 0 | 3 |
| RPF1 | SLC7A1 | 0.688691 | 3 | 0 | 3 |
| RPF1 | AMD1 | 0.687001 | 4 | 0 | 4 |
| RPF1 | MRPL11 | 0.68466 | 4 | 0 | 4 |
| RPF1 | ATL2 | 0.68038 | 3 | 0 | 3 |
| RPF1 | ZCCHC17 | 0.679826 | 4 | 0 | 3 |
| RPF1 | THOC7 | 0.67956 | 3 | 0 | 3 |
| RPF1 | SNX1 | 0.678838 | 3 | 0 | 3 |
| RPF1 | GNG12 | 0.678025 | 3 | 0 | 3 |
| RPF1 | NDUFS4 | 0.677415 | 3 | 0 | 3 |
For details and further investigation, click here
