| Full name: neuron navigator 2 | Alias Symbol: FLJ10633|FLJ11030|HELAD1|KIAA1419|POMFIL2|RAINB1|FLJ23707 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 89797 | HGNC ID: HGNC:15997 | Ensembl Gene: ENSG00000166833 | OMIM ID: 607026 |
| Drug and gene relationship at DGIdb | |||
Expression of NAV2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAV2 | 89797 | 218330_s_at | 0.0199 | 0.9755 | |
| GSE20347 | NAV2 | 89797 | 218330_s_at | -0.2212 | 0.4279 | |
| GSE23400 | NAV2 | 89797 | 218330_s_at | -0.0236 | 0.8779 | |
| GSE26886 | NAV2 | 89797 | 218330_s_at | 0.0457 | 0.9340 | |
| GSE29001 | NAV2 | 89797 | 218330_s_at | -0.0439 | 0.9172 | |
| GSE38129 | NAV2 | 89797 | 218330_s_at | -0.0376 | 0.8897 | |
| GSE45670 | NAV2 | 89797 | 218330_s_at | -0.1534 | 0.6846 | |
| GSE53622 | NAV2 | 89797 | 74539 | 0.2624 | 0.0423 | |
| GSE53624 | NAV2 | 89797 | 74539 | 0.4066 | 0.0000 | |
| GSE63941 | NAV2 | 89797 | 218330_s_at | -1.1613 | 0.1992 | |
| GSE77861 | NAV2 | 89797 | 218330_s_at | 0.5112 | 0.1049 | |
| GSE97050 | NAV2 | 89797 | A_23_P354791 | -0.0065 | 0.9808 | |
| SRP007169 | NAV2 | 89797 | RNAseq | 0.9488 | 0.0915 | |
| SRP008496 | NAV2 | 89797 | RNAseq | 1.5225 | 0.0006 | |
| SRP064894 | NAV2 | 89797 | RNAseq | 0.1971 | 0.4699 | |
| SRP133303 | NAV2 | 89797 | RNAseq | 1.1025 | 0.0043 | |
| SRP159526 | NAV2 | 89797 | RNAseq | -0.1652 | 0.7340 | |
| SRP193095 | NAV2 | 89797 | RNAseq | 0.3324 | 0.1348 | |
| SRP219564 | NAV2 | 89797 | RNAseq | 2.2976 | 0.0061 | |
| TCGA | NAV2 | 89797 | RNAseq | -0.0257 | 0.7764 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NAV2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAV2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAV2 | 89797 | 0 | 10 | 20 | |
| GSE20123 | NAV2 | 89797 | 0 | 10 | 20 | |
| GSE43470 | NAV2 | 89797 | 2 | 5 | 36 | |
| GSE46452 | NAV2 | 89797 | 7 | 5 | 47 | |
| GSE47630 | NAV2 | 89797 | 3 | 10 | 27 | |
| GSE54993 | NAV2 | 89797 | 3 | 0 | 67 | |
| GSE54994 | NAV2 | 89797 | 3 | 12 | 38 | |
| GSE60625 | NAV2 | 89797 | 0 | 0 | 11 | |
| GSE74703 | NAV2 | 89797 | 1 | 3 | 32 | |
| GSE74704 | NAV2 | 89797 | 0 | 9 | 11 | |
| TCGA | NAV2 | 89797 | 13 | 28 | 55 |
Total number of gains: 32; Total number of losses: 92; Total Number of normals: 364.
Somatic mutations of NAV2:
Generating mutation plots.
Highly correlated genes for NAV2:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAV2 | KCTD21 | 0.768363 | 3 | 0 | 3 |
| NAV2 | KIAA1143 | 0.762159 | 3 | 0 | 3 |
| NAV2 | GPR107 | 0.755934 | 3 | 0 | 3 |
| NAV2 | ANXA4 | 0.737161 | 3 | 0 | 3 |
| NAV2 | TPMT | 0.718666 | 3 | 0 | 3 |
| NAV2 | CUX1 | 0.715104 | 3 | 0 | 3 |
| NAV2 | ANKRD36B | 0.714617 | 3 | 0 | 3 |
| NAV2 | DENND1B | 0.713838 | 3 | 0 | 3 |
| NAV2 | PIGC | 0.713272 | 3 | 0 | 3 |
| NAV2 | XPC | 0.711267 | 3 | 0 | 3 |
| NAV2 | SRSF6 | 0.708097 | 3 | 0 | 3 |
| NAV2 | HSD17B12 | 0.685263 | 3 | 0 | 3 |
| NAV2 | PHF3 | 0.677665 | 3 | 0 | 3 |
| NAV2 | ZNF260 | 0.67764 | 3 | 0 | 3 |
| NAV2 | ARID2 | 0.667378 | 3 | 0 | 3 |
| NAV2 | EPM2AIP1 | 0.666072 | 3 | 0 | 3 |
| NAV2 | RPS6KC1 | 0.658775 | 3 | 0 | 3 |
| NAV2 | GRAMD4 | 0.655863 | 3 | 0 | 3 |
| NAV2 | MCFD2 | 0.652213 | 3 | 0 | 3 |
| NAV2 | SRP9 | 0.645148 | 4 | 0 | 3 |
For details and further investigation, click here
